A precision environmental health approach to prevention of human disease

Andrea Baccarelli (), Dana C. Dolinoy and Cheryl Lyn Walker
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Andrea Baccarelli: Columbia University Mailman School of Public Health
Dana C. Dolinoy: University of Michigan School of Public Health
Cheryl Lyn Walker: Baylor College of Medicine

Nature Communications, 2023, vol. 14, issue 1, 1-11

Abstract: Abstract Human health is determined by the interaction of our environment with the genome, epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic landscape of cells and tissues. Precision environmental health is an emerging field leveraging environmental and system-level (‘omic) data to understand underlying environmental causes of disease, identify biomarkers of exposure and response, and develop new prevention and intervention strategies. In this article we provide real-life illustrations of the utility of precision environmental health approaches, identify current challenges in the field, and outline new opportunities to promote health through a precision environmental health framework.

Date: 2023
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DOI: 10.1038/s41467-023-37626-2

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