A nonstop thrill ride from genes to the assembly of the T3SS injectisome

Itzhak Fishov () and Sharanya Namboodiri
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Itzhak Fishov: Ben Gurion University of the Negev
Sharanya Namboodiri: Ben Gurion University of the Negev

Nature Communications, 2023, vol. 14, issue 1, 1-3

Abstract: The type three secretion system (T3SS) is a membrane-anchored nano-machine utilized by many pathogenic bacteria to inject effector proteins and thus take control of host cells. In a recent article, Kaval et al. reveal a striking colocalization of a T3SS-encoding locus, its transcriptional activators, protein products, and the complete structure at the cell membrane, which they claim provides evidence for a mechanism known as ‘transertion’.

Date: 2023
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DOI: 10.1038/s41467-023-37753-w

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