Bioengineering of bacteria for cancer immunotherapy

Dinh-Huy Nguyen, Ari Chong, Yeongjin Hong () and Jung-Joon Min ()
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Dinh-Huy Nguyen: Chonnam National University Medical School and Hospital
Ari Chong: Chosun University Medical School and Hospital
Yeongjin Hong: Chonnam National University Medical School and Hospital
Jung-Joon Min: Chonnam National University Medical School and Hospital

Nature Communications, 2023, vol. 14, issue 1, 1-5

Abstract: Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expression for immunotherapeutic use. Finally, we discuss the current clinical status and limitations of BCiT.

Date: 2023
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DOI: 10.1038/s41467-023-39224-8

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