Divergent sequences of tetraspanins enable plants to specifically recognize microbe-derived extracellular vesicles

Jinyi Zhu, Qian Qiao, Yujing Sun, Yuanpeng Xu, Haidong Shu, Zhichao Zhang, Fan Liu, Haonan Wang, Wenwu Ye, Suomeng Dong, Yan Wang, Zhenchuan Ma and Yuanchao Wang ()
Additional contact information
Jinyi Zhu: Nanjing Agricultural University
Qian Qiao: Nanjing Agricultural University
Yujing Sun: Nanjing Agricultural University
Yuanpeng Xu: Nanjing Agricultural University
Haidong Shu: Nanjing Agricultural University
Zhichao Zhang: Nanjing Agricultural University
Fan Liu: Nanjing Agricultural University
Haonan Wang: Nanjing Agricultural University
Wenwu Ye: Nanjing Agricultural University
Suomeng Dong: Nanjing Agricultural University
Yan Wang: Nanjing Agricultural University
Zhenchuan Ma: Nanjing Agricultural University
Yuanchao Wang: Nanjing Agricultural University

Nature Communications, 2023, vol. 14, issue 1, 1-14

Abstract: Abstract Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean (Glycine max) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae. The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.

Date: 2023
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-023-40623-0 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-40623-0

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-023-40623-0

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().