Efficient electrospray deposition of surfaces smaller than the spray plume

Sarah H. Park, Lin Lei, Darrel D’Souza, Robert Zipkin, Emily T. DiMartini, Maria Atzampou, Emran O. Lallow, Jerry W. Shan, Jeffrey D. Zahn, David I. Shreiber, Hao Lin, Joel N. Maslow and Jonathan P. Singer ()
Additional contact information
Sarah H. Park: The State University of New Jersey
Lin Lei: The State University of New Jersey
Darrel D’Souza: The State University of New Jersey
Robert Zipkin: MedChem 101 LLC
Emily T. DiMartini: The State University of New Jersey
Maria Atzampou: The State University of New Jersey
Emran O. Lallow: The State University of New Jersey
Jerry W. Shan: The State University of New Jersey
Jeffrey D. Zahn: The State University of New Jersey
David I. Shreiber: The State University of New Jersey
Hao Lin: The State University of New Jersey
Joel N. Maslow: GeneOne Life Science
Jonathan P. Singer: The State University of New Jersey

Nature Communications, 2023, vol. 14, issue 1, 1-9

Abstract: Abstract Electrospray deposition (ESD) is a promising technique for depositing micro-/nano-scale droplets and particles with high quality and repeatability. It is particularly attractive for surface coating of costly and delicate biomaterials and bioactive compounds. While high efficiency of ESD has only been successfully demonstrated for spraying surfaces larger than the spray plume, this work extends its utility to smaller surfaces. It is shown that by architecting the local “charge landscape”, ESD coatings of surfaces smaller than plume size can be achieved. Efficiency approaching 100% is demonstrated with multiple model materials, including biocompatible polymers, proteins, and bioactive small molecules, on both flat and microneedle array targets. UV-visible spectroscopy and high-performance liquid chromatography measurements validate the high efficiency and quality of the sprayed material. Here, we show how this process is an efficient and more competitive alternative to other conformal coating mechanisms, such as dip coating or inkjet printing, for micro-engineered applications.

Date: 2023
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-023-40638-7 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-40638-7

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-023-40638-7

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().