Healthy dietary patterns and the risk of individual chronic diseases in community-dwelling adults

Xianwen Shang (), Jiahao Liu, Zhuoting Zhu, Xueli Zhang, Yu Huang, Shunming Liu, Wei Wang, Xiayin Zhang, Shulin Tang, Yijun Hu, Honghua Yu (), Zongyuan Ge and Mingguang He ()
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Xianwen Shang: Southern Medical University
Jiahao Liu: Centre for Eye Research Australia
Zhuoting Zhu: Southern Medical University
Xueli Zhang: Southern Medical University
Yu Huang: Southern Medical University
Shunming Liu: Southern Medical University
Wei Wang: Sun Yat-sen University
Xiayin Zhang: Southern Medical University
Shulin Tang: Southern Medical University
Yijun Hu: Southern Medical University
Honghua Yu: Southern Medical University
Zongyuan Ge: Monash University
Mingguang He: Southern Medical University

Nature Communications, 2023, vol. 14, issue 1, 1-14

Abstract: Abstract It is unclear regarding associations of dietary patterns with a wide range of chronic diseases and which dietary score is more predictive of major chronic diseases. Using the UK Biobank, we examine associations of four individual healthy dietary scores with the risk of 48 individual chronic diseases. Higher Alternate Mediterranean Diet score is associated with a lower risk of 32 (all 8 cardiometabolic disorders, 3 out of 10 types of cancers, 7 out of 10 psychological/neurological disorders, 5 out of 6 digestive disorders, and 9 out of 14 other chronic diseases). Alternate Healthy Eating Index-2010 and Healthful Plant-based Diet Index are inversely associated with the risk of 29 and 23 individual chronic diseases, respectively. A higher Anti-Empirical Dietary Inflammatory Index is associated with a lower risk of 14 individual chronic diseases and a higher incidence of two diseases. Our findings support dietary guidelines for the prevention of most chronic diseases.

Date: 2023
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DOI: 10.1038/s41467-023-42523-9

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