Identifying immune signatures of sepsis to increase diagnostic accuracy in very preterm babies

A. Das (), G. Ariyakumar, N Gupta, S. Kamdar, A. Barugahare, D. Deveson-Lucas, S. Gee, K. Costeloe, M. S. Davey, P. Fleming and D. L. Gibbons ()
Additional contact information
A. Das: King’s College London, Guy’s Hospital
G. Ariyakumar: King’s College London, Guy’s Hospital
S. Kamdar: King’s College London, Guy’s Hospital
A. Barugahare: Monash University
D. Deveson-Lucas: Monash University
S. Gee: King’s College London, Guy’s Hospital
K. Costeloe: Queen Mary University of London
M. S. Davey: Monash University
P. Fleming: Queen Mary University of London
D. L. Gibbons: King’s College London, Guy’s Hospital

Nature Communications, 2024, vol. 15, issue 1, 1-15

Abstract: Abstract Bacterial infections are a major cause of mortality in preterm babies, yet our understanding of early-life disease-associated immune dysregulation remains limited. Here, we combine multi-parameter flow cytometry, single-cell RNA sequencing and plasma analysis to longitudinally profile blood from very preterm babies (

Date: 2024
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DOI: 10.1038/s41467-023-44387-5

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