Controlled oxygen delivery to power tissue regeneration
Elizabeth Zoneff,
Yi Wang,
Colin Jackson,
Oliver Smith,
Serena Duchi,
Carmine Onofrillo,
Brooke Farrugia,
Simon E. Moulton,
Richard Williams,
Clare Parish,
David R. Nisbet () and
Lilith M. Caballero-Aguilar ()
Additional contact information
Elizabeth Zoneff: The University of Melbourne
Yi Wang: The University of Melbourne
Colin Jackson: Australian National University
Oliver Smith: Australian National University
Serena Duchi: The University of Melbourne
Carmine Onofrillo: The University of Melbourne
Brooke Farrugia: The University of Melbourne
Simon E. Moulton: St. Vincent’s Hospital
Richard Williams: Deakin University
Clare Parish: The University of Melbourne
David R. Nisbet: The University of Melbourne
Lilith M. Caballero-Aguilar: The University of Melbourne
Nature Communications, 2024, vol. 15, issue 1, 1-16
Abstract:
Abstract Oxygen plays a crucial role in human embryogenesis, homeostasis, and tissue regeneration. Emerging engineered regenerative solutions call for novel oxygen delivery systems. To become a reality, these systems must consider physiological processes, oxygen release mechanisms and the target application. In this review, we explore the biological relevance of oxygen at both a cellular and tissue level, and the importance of its controlled delivery via engineered biomaterials and devices. Recent advances and upcoming trends in the field are also discussed with a focus on tissue-engineered constructs that could meet metabolic demands to facilitate regeneration.
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-48719-x
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DOI: 10.1038/s41467-024-48719-x
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