Robotic wireless capsule endoscopy: recent advances and upcoming technologies

Qing Cao, Runyi Deng, Yue Pan, Ruijie Liu, Yicheng Chen, Guofang Gong, Jun Zou, Huayong Yang and Dong Han ()
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Qing Cao: Zhejiang University
Runyi Deng: Zhejiang University
Yue Pan: Zhejiang University
Ruijie Liu: Zhejiang University
Yicheng Chen: Zhejiang University
Guofang Gong: Zhejiang University
Jun Zou: Zhejiang University
Huayong Yang: Zhejiang University
Dong Han: Zhejiang University

Nature Communications, 2024, vol. 15, issue 1, 1-21

Abstract: Abstract Wireless capsule endoscopy (WCE) offers a non-invasive evaluation of the digestive system, eliminating the need for sedation and the risks associated with conventional endoscopic procedures. Its significance lies in diagnosing gastrointestinal tissue irregularities, especially in the small intestine. However, existing commercial WCE devices face limitations, such as the absence of autonomous lesion detection and treatment capabilities. Recent advancements in micro-electromechanical fabrication and computational methods have led to extensive research in sophisticated technology integration into commercial capsule endoscopes, intending to supersede wired endoscopes. This Review discusses the future requirements for intelligent capsule robots, providing a comparative evaluation of various methods’ merits and disadvantages, and highlighting recent developments in six technologies relevant to WCE. These include near-field wireless power transmission, magnetic field active drive, ultra-wideband/intrabody communication, hybrid localization, AI-based autonomous lesion detection, and magnetic-controlled diagnosis and treatment. Moreover, we explore the feasibility for future “capsule surgeons”.

Date: 2024
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DOI: 10.1038/s41467-024-49019-0

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