Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discovery

Jessica Karielle Tan, Venice Servellita, Doug Stryke, Emily Kelly, Jessica Streithorst, Nanami Sumimoto, Abiodun Foresythe, Hee Jae Huh, Jenny Nguyen, Miriam Oseguera, Noah Brazer, Jack Tang, Danielle Ingebrigtsen, Becky Fung, Helen Reyes, Melissa Hillberg, Alice Chen, Hugo Guevara, Shigeo Yagi, Christina Morales, Debra A. Wadford, Peter M. Mourani, Charles R. Langelier, Mikael de Lorenzi-Tognon, Patrick Benoit and Charles Y. Chiu ()
Additional contact information
Jessica Karielle Tan: University of California San Francisco
Venice Servellita: University of California San Francisco
Doug Stryke: University of California San Francisco
Emily Kelly: University of California San Francisco
Jessica Streithorst: University of California San Francisco
Nanami Sumimoto: University of California San Francisco
Abiodun Foresythe: University of California San Francisco
Hee Jae Huh: University of California San Francisco
Jenny Nguyen: University of California San Francisco
Miriam Oseguera: University of California San Francisco
Noah Brazer: University of California San Francisco
Jack Tang: University of California San Francisco
Danielle Ingebrigtsen: University of California San Francisco
Becky Fung: University of California San Francisco
Helen Reyes: University of California San Francisco
Melissa Hillberg: University of California San Francisco
Alice Chen: Center for Laboratory Sciences, California Department of Public Health
Hugo Guevara: Center for Laboratory Sciences, California Department of Public Health
Shigeo Yagi: Center for Laboratory Sciences, California Department of Public Health
Christina Morales: Center for Laboratory Sciences, California Department of Public Health
Debra A. Wadford: Center for Laboratory Sciences, California Department of Public Health
Peter M. Mourani: University of Arkansas for Medical Sciences
Charles R. Langelier: University of California San Francisco
Mikael de Lorenzi-Tognon: University of California San Francisco
Patrick Benoit: University of California San Francisco
Charles Y. Chiu: University of California San Francisco

Nature Communications, 2024, vol. 15, issue 1, 1-16

Abstract: Abstract Tools for rapid identification of novel and/or emerging viruses are urgently needed for clinical diagnosis of unexplained infections and pandemic preparedness. Here we developed and clinically validated a largely automated metagenomic next-generation sequencing (mNGS) assay for agnostic detection of respiratory viral pathogens from upper respiratory swab and bronchoalveolar lavage samples in

Date: 2024
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-024-51470-y Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-51470-y

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-024-51470-y

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().