Strengthening and expanding capacities in clinical trials: advancing pandemic prevention, preparedness and response in Africa

Nicaise Ndembi (), Tadesse T. Mekonen, Morenike Oluwatoyin Folayan, Nebiyu Dereje, Adriaan Kruger, Joseph Fokam, Elvis Temfack, Tajudeen Raji, Jean Nachega, Yap Boum, Trevor A. Crowell, Alain Ngashi Ngongo, Souleymane Mboup, Francine Ntoumi, Glaudina Loots, Michael Makanga, Samba Sow, Salim Abdool Karim and John Nkengasong
Additional contact information
Nicaise Ndembi: Haile Garment Square
Tadesse T. Mekonen: Grand bay
Morenike Oluwatoyin Folayan: Obafemi Awolowo University
Nebiyu Dereje: Haile Garment Square
Adriaan Kruger: Hazelwood
Joseph Fokam: Chantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management
Elvis Temfack: Haile Garment Square
Tajudeen Raji: Haile Garment Square
Jean Nachega: Faculty of Medicine and Health Sciences
Yap Boum: Institut Pasteur de
Trevor A. Crowell: Henry M. Jackson Foundation for the Advancement of Military Medicine
Alain Ngashi Ngongo: Haile Garment Square
Souleymane Mboup: de Surveillance Épidémiologique et de Formations (IRESSEF)
Francine Ntoumi: University of Tübingen
Glaudina Loots: Department of Science and Technology
Michael Makanga: Global Health EDCTP3 Joint Undertaking
Samba Sow: Center for Vaccine Development (CVD) at the Mali Ministry of Health and Social Development
Salim Abdool Karim: Columbia University
John Nkengasong: President’s Emergency Plan for AIDS Relief

Nature Communications, 2024, vol. 15, issue 1, 1-6

Abstract: Enhancing the clinical trial capabilities within Africa is essential to augment the continent’s pandemic prevention, preparedness and response efforts. Here, we describe the critical challenges of clinical trials in Africa and draw upon the lessons learnt from the Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT) experience, such as the importance of regional collaboration, capacity building and establishing standardized protocols.

Date: 2024
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DOI: 10.1038/s41467-024-53126-3

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