EconPapers    
Economics at your fingertips  
 

Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pangenome hybrid selection

Mark G. Young, Timothy J. Straub, Colin J. Worby, Hayden C. Metsky, Andreas Gnirke, Ryan A. Bronson, Lucas R. van Dijk, Christopher A. Desjardins, Christian Matranga, James Qu, Jesús Bazan Villicana, Philippe Azimzadeh, Andrew Kau, Karen W. Dodson, Henry L. Schreiber, Abigail L. Manson, Scott J. Hultgren and Ashlee M. Earl ()
Additional contact information
Mark G. Young: Broad Institute
Timothy J. Straub: Broad Institute
Colin J. Worby: Broad Institute
Hayden C. Metsky: Broad Institute
Andreas Gnirke: Broad Institute
Ryan A. Bronson: Broad Institute
Lucas R. van Dijk: Broad Institute
Christopher A. Desjardins: Broad Institute
Christian Matranga: Broad Institute
James Qu: Broad Institute
Jesús Bazan Villicana: Washington University School of Medicine
Philippe Azimzadeh: Washington University School of Medicine
Andrew Kau: Washington University School of Medicine
Karen W. Dodson: Washington University School of Medicine
Henry L. Schreiber: Washington University School of Medicine
Abigail L. Manson: Broad Institute
Scott J. Hultgren: Washington University School of Medicine
Ashlee M. Earl: Broad Institute

Nature Communications, 2024, vol. 15, issue 1, 1-15

Abstract: Abstract Low-abundance members of microbial communities are difficult to study in their native habitats, including Escherichia coli, a minor but common inhabitant of the gastrointestinal tract, and key opportunistic pathogen of the urinary tract. While multi-omic analyses have detailed interactions between uropathogenic Escherichia coli (UPEC) and the bladder mediating urinary tract infection (UTI), little is known about UPEC in its pre-infection reservoir, the gastrointestinal tract, partly due to its low relative abundance (

Date: 2024
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-024-53829-7 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-53829-7

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-024-53829-7

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().

 
Page updated 2025-03-19
Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-53829-7