On the origin of mitosis-derived human embryo aneuploidy

Jiyeon Leem, Madison Gowett, Sarah Bolarinwa and Binyam Mogessie ()
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Jiyeon Leem: Yale University
Madison Gowett: Yale University
Sarah Bolarinwa: Yale University
Binyam Mogessie: Yale University

Nature Communications, 2024, vol. 15, issue 1, 1-3

Abstract: Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embryos are predisposed to chromosomal abnormalities.

Date: 2024
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DOI: 10.1038/s41467-024-54953-0

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