Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners

Xuan Qin, Haoliang Shi, Hongyang Li, Binbin Chu, Jiawei Zhang, Zhen Wen (), Xuhui Sun (), Houyu Wang () and Yao He ()
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Xuan Qin: Soochow University
Haoliang Shi: Soochow University
Hongyang Li: Soochow University
Binbin Chu: Soochow University
Jiawei Zhang: Soochow University
Zhen Wen: Soochow University
Xuhui Sun: Soochow University
Houyu Wang: Soochow University
Yao He: Soochow University

Nature Communications, 2025, vol. 16, issue 1, 1-15

Abstract: Abstract Current treatments for fundus disorders, such as intravitreal injections, pose risks, including infection and retinal detachment, and are limited in their ability to deliver macromolecular drugs across the blood‒retinal barrier. Although non-invasive methods are safer, their delivery efficiency remains suboptimal (

Date: 2025
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DOI: 10.1038/s41467-024-55336-1

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