A global analysis of dairy consumption and incident cardiovascular disease

Pan Zhuang, Xiaohui Liu, Yin Li, Yang Ao, Yuqi Wu, Hao Ye, Xuzhi Wan, Lange Zhang, Denghui Meng, Yimei Tian, Xiaomei Yu, Fan Zhang, Anli Wang, Yu Zhang () and Jingjing Jiao ()
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Pan Zhuang: Zhejiang University School of Medicine
Xiaohui Liu: Zhejiang University School of Medicine
Yin Li: Zhejiang University School of Medicine
Yang Ao: Zhejiang University School of Medicine
Yuqi Wu: Zhejiang University
Hao Ye: Zhejiang University School of Medicine
Xuzhi Wan: Zhejiang University School of Medicine
Lange Zhang: Zhejiang University School of Medicine
Denghui Meng: Zhejiang University School of Medicine
Yimei Tian: Zhejiang University School of Medicine
Xiaomei Yu: Zhejiang University School of Medicine
Fan Zhang: Zhejiang University
Anli Wang: Zhejiang University School of Medicine
Yu Zhang: Zhejiang University School of Medicine
Jingjing Jiao: Zhejiang University School of Medicine

Nature Communications, 2025, vol. 16, issue 1, 1-13

Abstract: Abstract The role of dairy products in cardiovascular disease (CVD) prevention remains controversial. This study investigates the association between dairy consumption and CVD incidence using data from the China Kadoorie Biobank and the UK Biobank, complemented by an updated meta-analysis. Among Chinese participants, regular dairy consumption (primarily whole milk) is associated with a 9% increased risk of coronary heart disease (CHD) and a 6% reduced risk of stroke compared to non-consumers. Among British participants, total dairy consumption is linked to lower risks of CVD, CHD, and ischemic stroke, with cheese and semi-skimmed/skimmed milk contributing to reduced CVD risk. Meta-analysis reveals that total dairy consumption is associated with a 3.7% reduced risk of CVD and a 6% reduced risk of stroke. Notably, inverse associations with CVD incidence are observed for cheese and low-fat dairy products. Current evidence suggests that dairy consumption, particularly cheese, may have protective effects against CVD and stroke.

Date: 2025
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DOI: 10.1038/s41467-024-55585-0

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