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Artificial photosynthesis directed toward organic synthesis

Shogo Mori, Riku Hashimoto, Takashi Hisatomi, Kazunari Domen and Susumu Saito ()
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Shogo Mori: Chikusa
Riku Hashimoto: Chikusa
Takashi Hisatomi: Nagano
Kazunari Domen: Nagano
Susumu Saito: Chikusa

Nature Communications, 2025, vol. 16, issue 1, 1-8

Abstract: Abstract In nature, plants convert solar energy into chemical energy via water oxidation. Inspired by natural photosynthesis, artificial photosynthesis has been gaining increasing interest in the field of sustainability/green science and technology as a non-natural and thermodynamically endergonic (ΔG° > 0, uphill) solar-energy-driven reaction that uses water as an electron donor and a source material. Among the artificial-photosynthesis processes, inorganic-synthesis reactions via water oxidation, including water splitting and CO2-to-fuel conversion, have been attracting much attention. In contrast, the synthesis of high-value functionalized organic compounds via artificial photosynthesis, which we have termed artificial photosynthesis directed toward organic synthesis (APOS), remains a great challenge. Herein, we report a synthetically pioneering and meaningful strategy of APOS, where the carbohydroxylation of C = C double bonds is accomplished via a three-component coupling with H2 evolution using dual functions of semiconductor photocatalysts, i.e., silver-loaded titanium dioxide (Ag/TiO2) and rhodium–chromium–cobalt-loaded aluminum-doped strontium titanate (RhCrCo/SrTiO3:Al).

Date: 2025
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DOI: 10.1038/s41467-025-56374-z

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