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Distinct horizontal gene transfer potential of extracellular vesicles versus viral-like particles in marine habitats

Steven J. Biller (), M. Gray Ryan, Jasmine Li, Andrew Burger, John M. Eppley, Thomas Hackl and Edward F. DeLong
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Steven J. Biller: Wellesley College
M. Gray Ryan: Wellesley College
Jasmine Li: Wellesley College
Andrew Burger: University of Hawai’i at Manoa
John M. Eppley: University of Hawai’i at Manoa
Thomas Hackl: University of Groningen
Edward F. DeLong: University of Hawai’i at Manoa

Nature Communications, 2025, vol. 16, issue 1, 1-12

Abstract: Abstract Horizontal gene transfer (HGT) is enabled in part through the movement of DNA within two broad groups of small ( 7200 distinct chromosomal fragments and MGEs, many differentially partitioned between EVs and VLPs. Together these results suggest that distinctions in nanoparticle contents contribute to the mode and trajectory of microbial HGT networks and evolutionary dynamics in natural habitats.

Date: 2025
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DOI: 10.1038/s41467-025-57276-w

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