A multicenter cohort study of thyroidectomy-related decision regret in patients with low-risk papillary thyroid microcarcinoma

Genpeng Li, Ruicen Li, Jinjing Zhong, Wenjie Chen, Jinhao Shuai, Meizhu Chen, Feng Deng, Tao Wei, Huairong Tang (), Zhihui Li () and Jianyong Lei ()
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Genpeng Li: Sichuan University
Ruicen Li: Sichuan University
Jinjing Zhong: West China Hospital of Sichuan University
Wenjie Chen: Sichuan University
Jinhao Shuai: Meishan City People’s Hospital
Meizhu Chen: Sanya People’s Hospital
Feng Deng: Chongqing University Three Gorges Hospital
Tao Wei: Sichuan University
Huairong Tang: Sichuan University
Zhihui Li: Sichuan University
Jianyong Lei: Sichuan University

Nature Communications, 2025, vol. 16, issue 1, 1-11

Abstract: Abstract The level of thyroidectomy-related regret in patients with clinically low-risk papillary thyroid microcarcinoma (PTMC) and the determinants of decision regret are largely unknown. Here, we show that 319 (24.2%) of those who undergo thyroidectomy and 4 (3.4%) who undergo active surveillance (AS) express heightened regret based on validated decision regret scale (DRS) scores in the first online survey (P

Date: 2025
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DOI: 10.1038/s41467-025-57627-7

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