Perinatal outcomes of symptomatic chikungunya, dengue and Zika infection during pregnancy in Brazil: a registry-based cohort study

Thiago Cerqueira-Silva (), Laura C. Rodrigues, Neil Pearce, Maria Gloria Teixeira, Maria da Conceição Nascimento Costa, Luciana Cardim, Viviane S. Boaventura, Deborah A. Lawlor, Mauricio L. Barreto and Enny S. Paixao
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Thiago Cerqueira-Silva: London School of Hygiene & Tropical Medicine
Laura C. Rodrigues: London School of Hygiene & Tropical Medicine
Neil Pearce: London School of Hygiene & Tropical Medicine
Maria Gloria Teixeira: Fundação Oswaldo Cruz
Maria da Conceição Nascimento Costa: Fundação Oswaldo Cruz
Luciana Cardim: Fundação Oswaldo Cruz
Viviane S. Boaventura: Laboratório de Medicina e Saúde Pública de Precisão—Fundação Oswaldo Cruz
Deborah A. Lawlor: University of Bristol
Mauricio L. Barreto: Fundação Oswaldo Cruz
Enny S. Paixao: London School of Hygiene & Tropical Medicine

Nature Communications, 2025, vol. 16, issue 1, 1-10

Abstract: Abstract The previous literature shows mixed conclusions regarding the risk of adverse perinatal outcomes in pregnant women with symptomatic chikungunya, dengue, and Zika. We investigated this topic using a linked population-based Brazilian cohort from 2015 to 2020. The study included 6,993,395 live births. Among these, 6066 (

Date: 2025
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DOI: 10.1038/s41467-025-62640-x

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