High-performance gas-phase chiral enantiomer detectors based on chiral-induced spin selectivity effect

Xiaocheng Wu, Junjie Liu, Fan Ni, Longlong Jiang, Shiyu Wei, Xiaohong Wang () and Longzhen Qiu ()
Additional contact information
Xiaocheng Wu: Hefei University of Technology
Junjie Liu: Hefei University of Technology
Fan Ni: Hefei University of Technology
Longlong Jiang: Hefei University of Technology
Shiyu Wei: Hefei University of Technology
Xiaohong Wang: Hefei University of Technology
Longzhen Qiu: Hefei University of Technology

Nature Communications, 2025, vol. 16, issue 1, 1-10

Abstract: Abstract The chirality-induced spin selectivity (CISS) effect is a state-of-art strategy for chiral detectability enhancement. For the first time, high-performance gas-phase chiral detectors based on the CISS effect were prepared using organic polymer, to address the challenges in accurately and portably detecting gas-phase chiral enantiomers in analytical chemistry. Here, a series of block copolymers poly(3-hexylthiophene)-block poly(phenyl isocyanate) (P3HT-PPI) were synthesized, combining a chiral helical structure and significantly improved electrical conductivity to regulate CISS effect by PPI ratio for precise, portable chiral recognition. P3HT80-PPI30 demonstrates exceptional spin polarization up to 70.8%. The gas enantiomer detector based on P3HT80-PPI30 exhibits excellent chiral distinguish capability of limonene enantiomers with current asymmetry factor up to 0.50, real-time detection, high reversibility, and linear concertation-dependence of response. An ‘electronic dichroism’ system based on the circuit combining chiral and achiral sensing elements, was developed for real-time visualization of limonene enantiomeric excess. Designing materials with CISS effect incorporating spin-polarized electrons in chiral enantiomer recognition and combing with conductive properties for converting chemical signals to electrical outputs, provides an effective strategy for the next-generation real-time, efficient detection of multiple chiral enantiomers.

Date: 2025
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-025-63347-9 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-63347-9

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-025-63347-9

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().