A brain-inspired agentic architecture to improve planning with LLMs

Taylor Webb (), Shanka Subhra Mondal and Ida Momennejad ()
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Taylor Webb: Université de Montréal
Shanka Subhra Mondal: Princeton University
Ida Momennejad: Microsoft Research

Nature Communications, 2025, vol. 16, issue 1, 1-12

Abstract: Abstract Large language models (LLMs) demonstrate impressive performance on a wide variety of tasks, but they often struggle with tasks that require multi-step reasoning or goal-directed planning. To address this, we take inspiration from the human brain, in which planning is accomplished via component processes that are predominantly associated with specific brain regions. These processes include conflict monitoring, state prediction, state evaluation, task decomposition, and task coordination. We find that LLMs are often capable of carrying out these functions in isolation, but struggle to autonomously coordinate them in the service of a goal. Therefore, we propose a modular agentic architecture - the Modular Agentic Planner (MAP) - in which planning is performed via the interaction of specialized brain-inspired LLM modules. We evaluate MAP on three challenging planning tasks – graph traversal, Tower of Hanoi, and the PlanBench benchmark – as well as an NLP task requiring multi-step reasoning (strategyQA). We find that MAP yields significant improvements over both standard LLM methods and competitive agentic baselines, can be effectively combined with smaller and more cost-efficient LLMs, and displays superior transfer across tasks. These results demonstrate the benefit of utilizing knowledge from cognitive neuroscience to improve planning in LLMs.

Date: 2025
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DOI: 10.1038/s41467-025-63804-5

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