Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics

Ashley W. Seifert, Zhengui Zheng, Brandi K. Ormerod () and Martin J. Cohn ()
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Ashley W. Seifert: University of Florida
Zhengui Zheng: Howard Hughes Medical Institute, University of Florida
Brandi K. Ormerod: University of Florida
Martin J. Cohn: University of Florida

Nature Communications, 2010, vol. 1, issue 1, 1-9

Abstract: The faithful positioning and growth of cells during embryonic development is essential. In this study Seifertet al. demonstrate that inactivation of Sonic Hedgehogduring development of the genital tubercle results in a prolonged G1 phase and a slower rate of growth.

Date: 2010
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DOI: 10.1038/ncomms1020

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