TERRA transcripts are bound by a complex array of RNA-binding proteins

Isabel López de Silanes, Martina Stagno d'Alcontres and Maria A Blasco ()
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Isabel López de Silanes: Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO)
Martina Stagno d'Alcontres: Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO)
Maria A Blasco: Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO)

Nature Communications, 2010, vol. 1, issue 1, 1-10

Abstract: Recent work has revealed that the TTAGGG DNA repeats of telomeres are transcribed to form 'TERRA'. In this study, a set of RNA-binding proteins are shown to bind TERRA transcripts, altering the location of these transcripts at telomeres and regulating telomere abundance and length.

Date: 2010
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DOI: 10.1038/ncomms1032

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