Carbon nanotube–liposome supramolecular nanotrains for intelligent molecular-transport systems

Eijiro Miyako (), Kenji Kono, Eiji Yuba, Chie Hosokawa, Hidenori Nagai and Yoshihisa Hagihara
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Eijiro Miyako: Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST)
Kenji Kono: Osaka Prefecture University
Eiji Yuba: Osaka Prefecture University
Chie Hosokawa: Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST)
Hidenori Nagai: Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST)
Yoshihisa Hagihara: Health Research Institute (HRI), National Institute of Advanced Industrial Science and Technology (AIST)

Nature Communications, 2012, vol. 3, issue 1, 1-9

Abstract: Abstract Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.

Date: 2012
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DOI: 10.1038/ncomms2233

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