Subnanoradian X-ray phase-contrast imaging using a far-field interferometer of nanometric phase gratings

Han Wen (), Andrew A. Gomella, Ajay Patel, Susanna K. Lynch, Nicole Y. Morgan, Stasia A. Anderson, Eric E. Bennett, Xianghui Xiao, Chian Liu and Douglas E. Wolfe
Additional contact information
Han Wen: National Institutes of Health
Andrew A. Gomella: National Institutes of Health
Ajay Patel: National Institutes of Health
Susanna K. Lynch: National Institutes of Health
Nicole Y. Morgan: National Institutes of Health
Stasia A. Anderson: National Institutes of Health
Eric E. Bennett: National Institutes of Health
Xianghui Xiao: Advanced Photon Source, Argonne National Laboratory
Chian Liu: Advanced Photon Source, Argonne National Laboratory
Douglas E. Wolfe: Penn State University, State College

Nature Communications, 2013, vol. 4, issue 1, 1-9

Abstract: Abstract Hard X-ray phase-contrast imaging characterizes the electron density distribution in an object without the need for radiation absorption. The power of phase contrast to resolve subtle changes, such as those in soft tissue structures, lies in its ability to detect minute refractive bending of X-rays. Here we report a far-field, two-arm interferometer based on the new nanometric phase gratings, which can detect X-ray refraction with subnanoradian sensitivity, and at the same time overcomes the fundamental limitation of ultra-narrow bandwidths (Δλ/λ~10−4) of the current, most sensitive methods based on crystal interferometers. On a 1.5% bandwidth synchrotron source, we demonstrate clear visualization of blood vessels in unstained mouse organs in simple projection views, with over an order-of-magnitude higher phase contrast than current near-field grating interferometers.

Date: 2013
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/ncomms3659 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:4:y:2013:i:1:d:10.1038_ncomms3659

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/ncomms3659

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().