Selective chemical protein modification

Christopher D. Spicer and Benjamin G. Davis ()
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Christopher D. Spicer: Chemistry Research Laboratory, University of Oxford
Benjamin G. Davis: Chemistry Research Laboratory, University of Oxford

Nature Communications, 2014, vol. 5, issue 1, 1-14

Abstract: The chemical modification of proteins is an important tool for probing natural systems and synthesizing novel conjugates. Here, Spicer and Davis review the merits and limitations of the most useful methods for selective modification at both natural and unnatural amino acids.

Date: 2014
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DOI: 10.1038/ncomms5740

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