Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Catherine Igartua, Rachel A. Myers, Rasika A. Mathias, Maria Pino-Yanes, Celeste Eng, Penelope E. Graves, Albert M. Levin, Blanca E. Del-Rio-Navarro, Daniel J. Jackson, Oren E. Livne, Nicholas Rafaels, Christopher K. Edlund, James J. Yang, Scott Huntsman, Muhammad T. Salam, Isabelle Romieu, Raphael Mourad, James E. Gern, Robert F. Lemanske, Annah Wyss, Jane A. Hoppin, Kathleen C. Barnes, Esteban G. Burchard, W. James Gauderman, Fernando D. Martinez, Benjamin A. Raby, Scott T. Weiss, L. Keoki Williams, Stephanie J. London, Frank D. Gilliland, Dan L. Nicolae and Carole Ober ()
Additional contact information
Catherine Igartua: University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA
Rachel A. Myers: University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA
Rasika A. Mathias: Johns Hopkins University
Maria Pino-Yanes: University of California San Francisco
Celeste Eng: University of California San Francisco
Penelope E. Graves: Arizona Respiratory Center and BIO5 Institute, University of Arizona
Albert M. Levin: Henry Ford Health System
Blanca E. Del-Rio-Navarro: Hospital Infantil de Mexico Federico Gomez
Daniel J. Jackson: University of Wisconsin School of Medicine and Public Health
Oren E. Livne: University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA
Nicholas Rafaels: Johns Hopkins University
Christopher K. Edlund: Keck School of Medicine, University of Southern California
James J. Yang: School of Nursing, University of Michigan
Scott Huntsman: University of California San Francisco
Muhammad T. Salam: Keck School of Medicine, University of Southern California
Isabelle Romieu: International Agency for Research on Cancer
Raphael Mourad: University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA
James E. Gern: University of Wisconsin School of Medicine and Public Health
Robert F. Lemanske: University of Wisconsin School of Medicine and Public Health
Annah Wyss: National Institute of Environmental Health Sciences, National Institutes of Health
Jane A. Hoppin: National Institute of Environmental Health Sciences, National Institutes of Health
Kathleen C. Barnes: Johns Hopkins University
Esteban G. Burchard: University of California San Francisco
W. James Gauderman: Keck School of Medicine, University of Southern California
Fernando D. Martinez: Arizona Respiratory Center and BIO5 Institute, University of Arizona
Benjamin A. Raby: Harvard Medical School
Scott T. Weiss: Harvard Medical School
L. Keoki Williams: Center for Health Policy and Health Services Research, Henry Ford Health System
Stephanie J. London: National Institute of Environmental Health Sciences, National Institutes of Health
Frank D. Gilliland: Keck School of Medicine, University of Southern California
Dan L. Nicolae: University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA
Carole Ober: University of Chicago, 920 East 58th Street, CLSC 425, Chicago, Illinois 60637, USA

Nature Communications, 2015, vol. 6, issue 1, 1-8

Abstract: Abstract Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare (

Date: 2015
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DOI: 10.1038/ncomms6965

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