AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip

Anna Medici, Amy Marshall-Colon, Elsa Ronzier, Wojciech Szponarski, Rongchen Wang, Alain Gojon, Nigel M. Crawford, Sandrine Ruffel, Gloria M. Coruzzi and Gabriel Krouk ()
Additional contact information
Anna Medici: Biochimie et Physiologie Moléculaire des Plantes, Institut Claude Grignon
Amy Marshall-Colon: Center for Genomics and Systems Biology, New York University
Elsa Ronzier: Biochimie et Physiologie Moléculaire des Plantes, Institut Claude Grignon
Wojciech Szponarski: Biochimie et Physiologie Moléculaire des Plantes, Institut Claude Grignon
Rongchen Wang: Section of Cell and Developmental Biology, University of California at San Diego
Alain Gojon: Biochimie et Physiologie Moléculaire des Plantes, Institut Claude Grignon
Nigel M. Crawford: Section of Cell and Developmental Biology, University of California at San Diego
Sandrine Ruffel: Biochimie et Physiologie Moléculaire des Plantes, Institut Claude Grignon
Gloria M. Coruzzi: Center for Genomics and Systems Biology, New York University
Gabriel Krouk: Biochimie et Physiologie Moléculaire des Plantes, Institut Claude Grignon

Nature Communications, 2015, vol. 6, issue 1, 1-11

Abstract: Abstract Nitrogen and phosphorus are among the most widely used fertilizers worldwide. Nitrate (NO3−) and phosphate (PO43−) are also signalling molecules whose respective transduction pathways are being intensively studied. However, plants are continuously challenged with combined nutritional deficiencies, yet very little is known about how these signalling pathways are integrated. Here we report the identification of a highly NO3−-inducible NRT1.1-controlled GARP transcription factor, HRS1, document its genome-wide transcriptional targets, and validate its cis-regulatory elements. We demonstrate that this transcription factor and a close homologue repress the primary root growth in response to P deficiency conditions, but only when NO3− is present. This system defines a molecular logic gate integrating P and N signals. We propose that NO3− and P signalling converge via double transcriptional and post-transcriptional control of the same protein, HRS1.

Date: 2015
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/ncomms7274 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms7274

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/ncomms7274

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().