Subwavelength imaging through ion-beam-induced upconversion

Zhaohong Mi, Yuhai Zhang, Sudheer Kumar Vanga, Ce-Belle Chen, Hong Qi Tan, Frank Watt (), Xiaogang Liu () and Andrew A. Bettiol ()
Additional contact information
Zhaohong Mi: Centre for Ion Beam Applications, National University of Singapore
Yuhai Zhang: National University of Singapore
Sudheer Kumar Vanga: Centre for Ion Beam Applications, National University of Singapore
Ce-Belle Chen: Centre for Ion Beam Applications, National University of Singapore
Hong Qi Tan: Centre for Ion Beam Applications, National University of Singapore
Frank Watt: Centre for Ion Beam Applications, National University of Singapore
Xiaogang Liu: National University of Singapore
Andrew A. Bettiol: Centre for Ion Beam Applications, National University of Singapore

Nature Communications, 2015, vol. 6, issue 1, 1-6

Abstract: Abstract The combination of an optical microscope and a luminescent probe plays a pivotal role in biological imaging because it allows for probing subcellular structures. However, the optical resolutions are largely constrained by Abbe’s diffraction limit, and the common dye probes often suffer from photobleaching. Here we present a new method for subwavelength imaging by combining lanthanide-doped upconversion nanocrystals with the ionoluminescence imaging technique. We experimentally observed that the ion beam can be used as a new form of excitation source to induce photon upconversion in lanthanide-doped nanocrystals. This approach enables luminescence imaging and simultaneous mapping of cellular structures with a spatial resolution of sub-30 nm.

Date: 2015
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/ncomms9832 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms9832

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/ncomms9832

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().