Ultraflexible organic amplifier with biocompatible gel electrodes
Tsuyoshi Sekitani,
Tomoyuki Yokota,
Kazunori Kuribara,
Martin Kaltenbrunner,
Takanori Fukushima,
Yusuke Inoue,
Masaki Sekino,
Takashi Isoyama,
Yusuke Abe,
Hiroshi Onodera and
Takao Someya ()
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Tsuyoshi Sekitani: The University of Tokyo
Tomoyuki Yokota: The University of Tokyo
Kazunori Kuribara: The University of Tokyo
Martin Kaltenbrunner: The University of Tokyo
Takanori Fukushima: Chemical Resource Laboratory, Tokyo Institute of Technology
Yusuke Inoue: The University of Tokyo
Masaki Sekino: The University of Tokyo
Takashi Isoyama: Graduate School of Medicine, The University of Tokyo
Yusuke Abe: Graduate School of Medicine, The University of Tokyo
Hiroshi Onodera: The University of Tokyo
Takao Someya: The University of Tokyo
Nature Communications, 2016, vol. 7, issue 1, 1-11
Abstract:
Abstract In vivo electronic monitoring systems are promising technology to obtain biosignals with high spatiotemporal resolution and sensitivity. Here we demonstrate the fabrication of a biocompatible highly conductive gel composite comprising multi-walled carbon nanotube-dispersed sheet with an aqueous hydrogel. This gel composite exhibits admittance of 100 mS cm−2 and maintains high admittance even in a low-frequency range. On implantation into a living hypodermal tissue for 4 weeks, it showed a small foreign-body reaction compared with widely used metal electrodes. Capitalizing on the multi-functional gel composite, we fabricated an ultrathin and mechanically flexible organic active matrix amplifier on a 1.2-μm-thick polyethylene-naphthalate film to amplify (amplification factor: ∼200) weak biosignals. The composite was integrated to the amplifier to realize a direct lead epicardial electrocardiography that is easily spread over an uneven heart tissue.
Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:7:y:2016:i:1:d:10.1038_ncomms11425
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DOI: 10.1038/ncomms11425
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