A wearable chemical–electrophysiological hybrid biosensing system for real-time health and fitness monitoring

Somayeh Imani, Amay J. Bandodkar, A. M. Vinu Mohan, Rajan Kumar, Shengfei Yu, Joseph Wang () and Patrick P. Mercier ()
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Somayeh Imani: University of California, San Diego
Amay J. Bandodkar: University of California, San Diego
A. M. Vinu Mohan: University of California, San Diego
Rajan Kumar: University of California, San Diego
Shengfei Yu: University of California, San Diego
Joseph Wang: University of California, San Diego
Patrick P. Mercier: University of California, San Diego

Nature Communications, 2016, vol. 7, issue 1, 1-7

Abstract: Abstract Flexible, wearable sensing devices can yield important information about the underlying physiology of a human subject for applications in real-time health and fitness monitoring. Despite significant progress in the fabrication of flexible biosensors that naturally comply with the epidermis, most designs measure only a small number of physical or electrophysiological parameters, and neglect the rich chemical information available from biomarkers. Here, we introduce a skin-worn wearable hybrid sensing system that offers simultaneous real-time monitoring of a biochemical (lactate) and an electrophysiological signal (electrocardiogram), for more comprehensive fitness monitoring than from physical or electrophysiological sensors alone. The two sensing modalities, comprising a three-electrode amperometric lactate biosensor and a bipolar electrocardiogram sensor, are co-fabricated on a flexible substrate and mounted on the skin. Human experiments reveal that physiochemistry and electrophysiology can be measured simultaneously with negligible cross-talk, enabling a new class of hybrid sensing devices.

Date: 2016
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DOI: 10.1038/ncomms11650

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