Accelerating the search for the missing proteins in the human proteome

Mark S. Baker (), Seong Beom Ahn, Abidali Mohamedali, Mohammad T. Islam, David Cantor, Peter D. Verhaert, Susan Fanayan, Samridhi Sharma, Edouard C. Nice, Mark Connor and Shoba Ranganathan
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Mark S. Baker: Faculty of Medicine & Health Sciences, Macquarie University
Seong Beom Ahn: Faculty of Medicine & Health Sciences, Macquarie University
Abidali Mohamedali: Faculty of Medicine & Health Sciences, Macquarie University
Mohammad T. Islam: Macquarie University
David Cantor: Faculty of Medicine & Health Sciences, Macquarie University
Peter D. Verhaert: Antwerp University, Antwerpen 2020
Susan Fanayan: Faculty of Medicine & Health Sciences, Macquarie University
Samridhi Sharma: Faculty of Medicine & Health Sciences, Macquarie University
Edouard C. Nice: Monash University
Mark Connor: Faculty of Medicine & Health Sciences, Macquarie University
Shoba Ranganathan: Macquarie University

Nature Communications, 2017, vol. 8, issue 1, 1-13

Abstract: The Human Proteome Project (HPP) aims to discover high-stringency data for all proteins encoded by the human genome. Currently, ∼18% of the proteins in the human proteome (the missing proteins) do not have high-stringency evidence (for example, mass spectrometry) confirming their existence, while much additional information is available about many of these missing proteins. Here, we present MissingProteinPedia as a community resource to accelerate the discovery and understanding of these missing proteins.

Date: 2017
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DOI: 10.1038/ncomms14271

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