Accurate immune repertoire sequencing reveals malaria infection driven antibody lineage diversification in young children

Ben S. Wendel, Chenfeng He, Mingjuan Qu, Di Wu, Stefany M. Hernandez, Ke-Yue Ma, Eugene W. Liu, Jun Xiao, Peter D. Crompton, Susan K. Pierce, Pengyu Ren, Keke Chen and Ning Jiang ()
Additional contact information
Ben S. Wendel: University of Texas at Austin
Chenfeng He: University of Texas at Austin
Mingjuan Qu: University of Texas at Austin
Di Wu: University of Texas at Austin
Stefany M. Hernandez: University of Texas at Austin
Ke-Yue Ma: University of Texas at Austin
Eugene W. Liu: National Institutes of Health
Jun Xiao: ImmuDX, LLC
Peter D. Crompton: National Institutes of Health
Susan K. Pierce: National Institutes of Health
Pengyu Ren: University of Texas at Austin
Keke Chen: Wright State University
Ning Jiang: University of Texas at Austin

Nature Communications, 2017, vol. 8, issue 1, 1-14

Abstract: Abstract Accurately measuring antibody repertoire sequence composition in a small amount of blood is challenging yet important for understanding repertoire responses to infection and vaccination. We develop molecular identifier clustering-based immune repertoire sequencing (MIDCIRS) and use it to study age-related antibody repertoire development and diversification before and during acute malaria in infants (

Date: 2017
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-017-00645-x Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_s41467-017-00645-x

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-017-00645-x

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().