CVD-grown monolayer MoS2 in bioabsorbable electronics and biosensors
Xiang Chen,
Yong Ju Park,
Minpyo Kang,
Seung-Kyun Kang,
Jahyun Koo,
Sachin M. Shinde,
Jiho Shin,
Seunghyun Jeon,
Gayoung Park,
Ying Yan,
Matthew R. MacEwan,
Wilson Z. Ray,
Kyung-Mi Lee (),
John A Rogers () and
Jong-Hyun Ahn ()
Additional contact information
Xiang Chen: Yonsei University
Yong Ju Park: Yonsei University
Minpyo Kang: Yonsei University
Seung-Kyun Kang: Korea Advanced Institute of Science and Technology
Jahyun Koo: Northwestern University
Sachin M. Shinde: Yonsei University
Jiho Shin: University of Illinois at Urbana-Champaign
Seunghyun Jeon: Korea University College of Medicine
Gayoung Park: Korea University College of Medicine
Ying Yan: Washington University School of Medicine
Matthew R. MacEwan: Washington University School of Medicine
Wilson Z. Ray: Washington University School of Medicine
Kyung-Mi Lee: Korea University College of Medicine
John A Rogers: Northwestern University
Jong-Hyun Ahn: Yonsei University
Nature Communications, 2018, vol. 9, issue 1, 1-12
Abstract:
Abstract Transient electronics represents an emerging technology whose defining feature is an ability to dissolve, disintegrate or otherwise physically disappear in a controlled manner. Envisioned applications include resorbable/degradable biomedical implants, hardware-secure memory devices, and zero-impact environmental sensors. 2D materials may have essential roles in these systems due to their unique mechanical, thermal, electrical, and optical properties. Here, we study the bioabsorption of CVD-grown monolayer MoS2, including long-term cytotoxicity and immunological biocompatibility evaluations in biofluids and tissues of live animal models. The results show that MoS2 undergoes hydrolysis slowly in aqueous solutions without adverse biological effects. We also present a class of MoS2-based bioabsorbable and multi-functional sensor for intracranial monitoring of pressure, temperature, strain, and motion in animal models. Such technology offers specific, clinically relevant roles in diagnostic/therapeutic functions during recovery from traumatic brain injury. Our findings support the broader use of 2D materials in transient electronics and qualitatively expand the design options in other areas.
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-03956-9
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DOI: 10.1038/s41467-018-03956-9
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