Elucidating the genetic architecture of reproductive ageing in the Japanese population

Momoko Horikoshi (), Felix R. Day, Masato Akiyama, Makoto Hirata, Yoichiro Kamatani, Koichi Matsuda, Kazuyoshi Ishigaki, Masahiro Kanai, Hollis Wright, Carlos A. Toro, Sergio R. Ojeda, Alejandro Lomniczi, Michiaki Kubo, Ken K. Ong and John. R. B. Perry ()
Additional contact information
Momoko Horikoshi: RIKEN Centre for Integrative Medical Sciences
Felix R. Day: Cambridge Biomedical Campus
Masato Akiyama: RIKEN Center for Integrative Medical Sciences
Makoto Hirata: The University of Tokyo
Yoichiro Kamatani: RIKEN Center for Integrative Medical Sciences
Koichi Matsuda: The University of Tokyo
Kazuyoshi Ishigaki: RIKEN Center for Integrative Medical Sciences
Masahiro Kanai: RIKEN Center for Integrative Medical Sciences
Hollis Wright: Oregon Health and Sciences University
Carlos A. Toro: Oregon Health and Sciences University
Sergio R. Ojeda: Oregon Health and Sciences University
Alejandro Lomniczi: Oregon Health and Sciences University
Michiaki Kubo: RIKEN Center for Integrative Medical Sciences
Ken K. Ong: Cambridge Biomedical Campus
John. R. B. Perry: Cambridge Biomedical Campus

Nature Communications, 2018, vol. 9, issue 1, 1-9

Abstract: Abstract Population studies elucidating the genetic architecture of reproductive ageing have been largely limited to European ancestries, restricting the generalizability of the findings and overlooking possible key genes poorly captured by common European genetic variation. Here, we report 26 loci (all P

Date: 2018
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DOI: 10.1038/s41467-018-04398-z

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