Control of seed dormancy and germination by DOG1-AHG1 PP2C phosphatase complex via binding to heme

Noriyuki Nishimura (), Wataru Tsuchiya, James J. Moresco, Yuki Hayashi, Kouji Satoh, Nahomi Kaiwa, Tomoko Irisa, Toshinori Kinoshita, Julian I. Schroeder, John R. Yates, Takashi Hirayama and Toshimasa Yamazaki
Additional contact information
Noriyuki Nishimura: National Agriculture and Food Research Organization
Wataru Tsuchiya: National Agriculture and Food Research Organization
James J. Moresco: The Scripps Research Institute
Yuki Hayashi: Nagoya University
Kouji Satoh: National Agriculture and Food Research Organization
Nahomi Kaiwa: National Agriculture and Food Research Organization
Tomoko Irisa: National Agriculture and Food Research Organization
Toshinori Kinoshita: Nagoya University
Julian I. Schroeder: University of California, San Diego
John R. Yates: The Scripps Research Institute
Takashi Hirayama: Okayama University
Toshimasa Yamazaki: National Agriculture and Food Research Organization

Nature Communications, 2018, vol. 9, issue 1, 1-14

Abstract: Abstract Abscisic acid (ABA) regulates abiotic stress and developmental responses including regulation of seed dormancy to prevent seeds from germinating under unfavorable environmental conditions. ABA HYPERSENSITIVE GERMINATION1 (AHG1) encoding a type 2C protein phosphatase (PP2C) is a central negative regulator of ABA response in germination; however, the molecular function and regulation of AHG1 remain elusive. Here we report that AHG1 interacts with DELAY OF GERMINATION1 (DOG1), which is a pivotal positive regulator in seed dormancy. DOG1 acts upstream of AHG1 and impairs the PP2C activity of AHG1 in vitro. Furthermore, DOG1 has the ability to bind heme. Binding of DOG1 to AHG1 and heme are independent processes, but both are essential for DOG1 function in vivo. Our study demonstrates that AHG1 and DOG1 constitute an important regulatory system for seed dormancy and germination by integrating multiple environmental signals, in parallel with the PYL/RCAR ABA receptor-mediated regulatory system.

Date: 2018
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/s41467-018-04437-9 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-04437-9

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-018-04437-9

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().