Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

Nicola Pirastu (), Peter K. Joshi, Paul S. Vries, Marilyn C. Cornelis, Paul M. McKeigue, NaNa Keum, Nora Franceschini, Marco Colombo, Edward L. Giovannucci, Athina Spiliopoulou, Lude Franke, Kari E. North, Peter Kraft, Alanna C. Morrison, Tõnu Esko and James F. Wilson
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Nicola Pirastu: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
Peter K. Joshi: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
Paul S. Vries: The University of Texas Health Science Center at Houston
Marilyn C. Cornelis: Northwestern University Feinberg School of Medicine
Paul M. McKeigue: University of Edinburgh
NaNa Keum: Dongguk University
Nora Franceschini: University of North Carolina
Marco Colombo: University of Edinburgh
Edward L. Giovannucci: Harvard T. H. Chan School of Public Health
Athina Spiliopoulou: University of Edinburgh
Lude Franke: University Medical Center
Kari E. North: University of North Carolina
Peter Kraft: Harvard T. H. Chan School of Public Health
Alanna C. Morrison: The University of Texas Health Science Center at Houston
Tõnu Esko: University of Tartu
James F. Wilson: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh

Nature Communications, 2018, vol. 9, issue 1, 1-1

Abstract: We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.

Date: 2018
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DOI: 10.1038/s41467-018-04857-7

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