Long-term deep-supercooling of large-volume water and red cell suspensions via surface sealing with immiscible liquids

Haishui Huang, Martin L. Yarmush () and O. Berk Usta ()
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Haishui Huang: Harvard Medical School and Shriners Hospitals for Children
Martin L. Yarmush: Harvard Medical School and Shriners Hospitals for Children
O. Berk Usta: Harvard Medical School and Shriners Hospitals for Children

Nature Communications, 2018, vol. 9, issue 1, 1-10

Abstract: Abstract Supercooling of aqueous solutions is a fundamentally and practically important physical phenomenon with numerous applications in biopreservation and beyond. Under normal conditions, heterogeneous nucleation mechanisms critically prohibit the simultaneous long-term (> 1 week), large volume (> 1 ml), and low temperatures (

Date: 2018
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DOI: 10.1038/s41467-018-05636-0

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