Single-particle mass spectrometry with arrays of frequency-addressed nanomechanical resonators

Eric Sage, Marc Sansa, Shawn Fostner, Martial Defoort, Marc Gély, Akshay K. Naik, Robert Morel, Laurent Duraffourg, Michael L. Roukes, Thomas Alava, Guillaume Jourdan, Eric Colinet, Christophe Masselon, Ariel Brenac and Sébastien Hentz ()
Additional contact information
Eric Sage: Univ. Grenoble Alpes, CEA, LETI
Marc Sansa: Univ. Grenoble Alpes, CEA, LETI
Shawn Fostner: Univ. Grenoble Alpes, CEA, LETI
Martial Defoort: Univ. Grenoble Alpes, CEA, LETI
Marc Gély: Univ. Grenoble Alpes, CEA, LETI
Akshay K. Naik: Indian Institute of Science
Robert Morel: Univ. Grenoble Alpes, CEA, CNRS, Grenoble INP, INAC-Spintec
Laurent Duraffourg: Univ. Grenoble Alpes, CEA, LETI
Michael L. Roukes: California Institute of Technology
Thomas Alava: Univ. Grenoble Alpes, CEA, LETI
Guillaume Jourdan: Univ. Grenoble Alpes, CEA, LETI
Eric Colinet: Univ. Grenoble Alpes, CEA, LETI
Christophe Masselon: Université Grenoble-Alpes
Ariel Brenac: Univ. Grenoble Alpes, CEA, CNRS, Grenoble INP, INAC-Spintec
Sébastien Hentz: Univ. Grenoble Alpes, CEA, LETI

Nature Communications, 2018, vol. 9, issue 1, 1-8

Abstract: Abstract One of the main challenges to overcome to perform nanomechanical mass spectrometry analysis in a practical time frame stems from the size mismatch between the analyte beam and the small nanomechanical detector area. We report here the demonstration of mass spectrometry with arrays of 20 multiplexed nanomechanical resonators; each resonator is designed with a distinct resonance frequency which becomes its individual address. Mass spectra of metallic aggregates in the MDa range are acquired with more than one order of magnitude improvement in analysis time compared to individual resonators. A 20 NEMS array is probed in 150 ms with the same mass limit of detection as a single resonator. Spectra acquired with a conventional time-of-flight mass spectrometer in the same system show excellent agreement. We also demonstrate how mass spectrometry imaging at the single-particle level becomes possible by mapping a 4-cm-particle beam in the MDa range and above.

Date: 2018
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/s41467-018-05783-4 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-05783-4

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-018-05783-4

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().