Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores

Nicole Stéphanie Galenkamp, Misha Soskine, Jos Hermans, Carsten Wloka and Giovanni Maglia ()
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Nicole Stéphanie Galenkamp: University of Groningen
Misha Soskine: University of Groningen
Jos Hermans: University of Groningen
Carsten Wloka: University of Groningen
Giovanni Maglia: University of Groningen

Nature Communications, 2018, vol. 9, issue 1, 1-8

Abstract: Abstract Crucial steps in the miniaturisation of biosensors are the conversion of a biological signal into an electrical current as well as the direct sampling of bodily fluids. Here we show that protein sensors in combination with a nanopore, acting as an electrical transducer, can accurately quantify metabolites in real time directly from nanoliter amounts of blood and other bodily fluids. Incorporation of the nanopore into portable electronic devices will allow developing sensitive, continuous, and non-invasive sensors for metabolites for point-of-care and home diagnostics.

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-06534-1

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DOI: 10.1038/s41467-018-06534-1

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