The resilience framework as a strategy to combat stress-related disorders

Raffael Kalisch (), Dewleen G. Baker, Ulrike Basten, Marco P. Boks, George A. Bonanno, Eddie Brummelman, Andrea Chmitorz, Guillén Fernàndez, Christian J. Fiebach, Isaac Galatzer-Levy, Elbert Geuze, Sergiu Groppa, Isabella Helmreich, Talma Hendler, Erno J. Hermans, Tanja Jovanovic, Thomas Kubiak, Klaus Lieb, Beat Lutz, Marianne B. Müller, Ryan J. Murray, Caroline M. Nievergelt, Andreas Reif, Karin Roelofs, Bart P. F. Rutten, David Sander, Anita Schick, Oliver Tüscher, Ilse Van Diest, Anne-Laura van Harmelen, Ilya M. Veer, Eric Vermetten, Christiaan H. Vinkers, Tor D. Wager, Henrik Walter, Michèle Wessa, Michael Wibral and Birgit Kleim
Additional contact information
Raffael Kalisch: University Medical Center of the Johannes Gutenberg University
Dewleen G. Baker: VA Center of Excellence for Stress and Mental Health and VA San Diego Healthcare System
Ulrike Basten: CRC 1193 consortium, Johannes Gutenberg University
Marco P. Boks: University Medical Center Utrecht, Brain Center Rudolf Magnus
George A. Bonanno: Teachers College, Columbia University
Eddie Brummelman: intresa consortium
Andrea Chmitorz: University Medical Center of the Johannes Gutenberg University
Guillén Fernàndez: intresa consortium
Christian J. Fiebach: CRC 1193 consortium, Johannes Gutenberg University
Isaac Galatzer-Levy: New York University School of Medicine
Elbert Geuze: University Medical Center Utrecht, Brain Center Rudolf Magnus
Sergiu Groppa: University Medical Center of the Johannes Gutenberg University
Isabella Helmreich: University Medical Center of the Johannes Gutenberg University
Talma Hendler: intresa consortium
Erno J. Hermans: intresa consortium
Tanja Jovanovic: Emory University School of Medicine
Thomas Kubiak: University Medical Center of the Johannes Gutenberg University
Klaus Lieb: University Medical Center of the Johannes Gutenberg University
Beat Lutz: University Medical Center of the Johannes Gutenberg University
Marianne B. Müller: University Medical Center of the Johannes Gutenberg University
Ryan J. Murray: intresa consortium
Caroline M. Nievergelt: VA Center of Excellence for Stress and Mental Health and VA San Diego Healthcare System
Andreas Reif: intresa consortium
Karin Roelofs: intresa consortium
Bart P. F. Rutten: School for Mental Health and Neuroscience
David Sander: intresa consortium
Anita Schick: University Medical Center of the Johannes Gutenberg University
Oliver Tüscher: University Medical Center of the Johannes Gutenberg University
Ilse Van Diest: intresa consortium
Anne-Laura van Harmelen: intresa consortium
Ilya M. Veer: intresa consortium
Eric Vermetten: Ministry of Defence
Christiaan H. Vinkers: University Medical Center Utrecht, Brain Center Rudolf Magnus
Tor D. Wager: University of Colorado
Henrik Walter: intresa consortium
Michèle Wessa: University Medical Center of the Johannes Gutenberg University
Michael Wibral: CRC 1193 consortium, Johannes Gutenberg University
Birgit Kleim: intresa consortium

Nature Human Behaviour, 2017, vol. 1, issue 11, 784-790

Abstract: Consistent failure over the past few decades to reduce the high prevalence of stress-related disorders has motivated a search for alternative research strategies. Resilience refers to the phenomenon of many people maintaining mental health despite exposure to psychological or physical adversity. Instead of aiming to understand the pathophysiology of stress-related disorders, resilience research focuses on protective mechanisms that shield people against the development of such disorders and tries to exploit its insights to improve treatment and, in particular, disease prevention. To fully harness the potential of resilience research, a critical appraisal of the current state of the art — in terms of basic concepts and key methods — is needed. We highlight challenges to resilience research and make concrete conceptual and methodological proposals to improve resilience research. Most importantly, we propose to focus research on the dynamic processes of successful adaptation to stressors in prospective longitudinal studies.

Date: 2017
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DOI: 10.1038/s41562-017-0200-8

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