A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders

Carmen Schaeuffele (), Laura E. Meine (), Ava Schulz, Maxi C. Weber, Angela Moser, Christina Paersch, Dominique Recher, Johanna Boettcher, Babette Renneberg, Christoph Flückiger and Birgit Kleim
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Carmen Schaeuffele: Freie Universitaet Berlin
Laura E. Meine: University of Zurich
Ava Schulz: University of Zurich
Maxi C. Weber: Freie Universitaet Berlin
Angela Moser: University of Zurich
Christina Paersch: University of Zurich
Dominique Recher: University of Zurich
Johanna Boettcher: Psychologische Hochschule Berlin
Babette Renneberg: Freie Universitaet Berlin
Christoph Flückiger: University of Kassel
Birgit Kleim: University of Zurich

Nature Human Behaviour, 2024, vol. 8, issue 3, 493-509

Abstract: Abstract Transdiagnostic cognitive behavioural psychotherapy (TD-CBT) may facilitate the treatment of emotional disorders. Here we investigate short- and long-term efficacy of TD-CBT for emotional disorders in individual, group and internet-based settings in randomized controlled trials (PROSPERO CRD42019141512). Two independent reviewers screened results from PubMed, MEDLINE, PsycINFO, Google Scholar, medRxiv and OSF Preprints published between January 2000 and June 2023, selected studies for inclusion, extracted data and evaluated risk of bias (Cochrane risk-of-bias tool 2.0). Absolute efficacy from pre- to posttreatment and relative efficacy between TD-CBT and control treatments were investigated with random-effects models. Of 56 identified studies, 53 (6,705 participants) were included in the meta-analysis. TD-CBT had larger effects on depression (g = 0.74, 95% CI = 0.57–0.92, P

Date: 2024
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DOI: 10.1038/s41562-023-01787-3

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