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2026, volume 649, articles 8095

Author Correction: Activity of caspase-8 determines plasticity between cell death pathways pp. E1-E1

Kim Newton, Katherine E. Wickliffe, Allie Maltzman, Debra L. Dugger, Rohit Reja, Yue Zhang, Merone Roose-Girma, Zora Modrusan, Meredith S. Sagolla, Joshua D. Webster and Vishva M. Dixit

Publisher Correction: CRISPR activation for SCN2A-related neurodevelopmental disorders pp. E2-E2

Serena Tamura, Andrew D. Nelson, Perry W. E. Spratt, Elizabeth C. Hamada, Xujia Zhou, Henry Kyoung, Zizheng Li, Coline Arnould, Vladyslav Barskyi, Beniamin Krupkin, Kiana Young, Jingjing Zhao, Stephanie S. Holden, Atehsa Sahagun, Caroline M. Keeshen, Congyi Lu, Roy Ben-Shalom, Sunrae E. Taloma, Selin Schamiloglu, Ying C. Li, Lia Min, Paul M. Jenkins, Jen Q. Pan, Jeanne T. Paz, Stephan J. Sanders, Navneet Matharu, Nadav Ahituv and Kevin J. Bender

US–Africa bilateral health deals won’t help against diseases that ignore borders pp. 9-9

Paul Adepoju

Science in 2026: the events to watch for in the coming year pp. 11-13

Miryam Naddaf

China leads research in 90% of crucial technologies — a dramatic shift this century pp. 13-14

Xiaoying You

How common is Alzheimer’s? Blood-test study holds surprises pp. 14-14

Asher Mullard

Quantum computing ‘KPIs’ could distinguish true breakthroughs from spurious claims pp. 15-16

Elizabeth Gibney

Giant 3D map shows almost every building in the world pp. 16-16

Mohana Basu

These are a few of my favourite sounds: Books in brief pp. 25-25

Andrew Robinson

Revised estimates of CO2 sources and sinks improve global carbon accounting pp. 32-33

Galen A. McKinley

Primate embryo model leaps across developmental boundaries pp. 34-35

Xiangyu Kong and Thorold W. Theunissen

What changing energy flows reveal about Africa’s ecosystems pp. 35-37

Wendy Foden

Circular DNA has a ticket to ride chromosomes pp. 37-38

Noah A. Dusseau and Eunhee Yi

A fault-tolerant neutral-atom architecture for universal quantum computation pp. 39-46

Dolev Bluvstein, Alexandra A. Geim, Sophie H. Li, Simon J. Evered, J. Pablo Bonilla Ataides, Gefen Baranes, Andi Gu, Tom Manovitz, Muqing Xu, Marcin Kalinowski, Shayan Majidy, Christian Kokail, Nishad Maskara, Elias C. Trapp, Luke M. Stewart, Simon Hollerith, Hengyun Zhou, Michael J. Gullans, Susanne F. Yelin, Markus Greiner, Vladan Vuletić, Madelyn Cain and Mikhail D. Lukin

High-performance tandem perovskite LEDs through interlayer photon recycling pp. 53-58

You Ke, Wei Zhu, Chao Ma, Kuankuan Xiong, Wang Liu, Zhiyuan Kuang, Jianhong Wu, Dongmin Qian, Mengmeng Li, Saixue Wang, Jinpei Wang, Xiangru Tao, Shuang Xu, Lin Zhu, Qiming Peng, Nana Wang, Wei Huang and Jianpu Wang

Flexible perovskite/silicon tandem solar cells with 33.6% efficiency pp. 59-64

Shibo Wang, Wenhao Li, Cao Yu, Wei Shi, Qian Kang, Fengxian Cao, Kun Gao, Liu Yang, Bowen Yang, Jian Zhou, Shaofei Yang, Qi Wang, Qin Fei, Xi Chen, Gaoyuan Chen, Pengxu Chen, Zijia Li, Wei-Chih Hsu, Zhongliang Yan, Yang Bai, Wenzhu Liu, Stefaan De Wolf, Xinbo Yang and Xiaohong Zhang

Flexible perovskite/silicon tandem solar cell with a dual-buffer layer pp. 65-72

Zheng Fang, Lei Ding, Ying Yang, Xiaobing Gu, Haiyue Li, Hao Chen, Yue Yin, Wei Wang, Xiaoyong Wu, Zhijie Rao, Linyu Ning, Dongsheng Yang, Huimin Zhang, Yongdeng Long, Wei Li, Fu Zhang, Simeng Xia, Lingbo Jia, Chi Liu, Bochao Li, Bo Liu, Shijie Ju, Wei Du, Hua Zhang, Yuan Qin, Xiaoning Ru, Yongyuan Xu, Yue Lu, Yongcai He, Zhenguo Li, Xixiang Xu, Minghao Qu, Bo He, Jiang Liu and Xiaohong Zhang

Myriad aryne derivatives from carboxylic acids pp. 91-97

Chris M. Seong, Sallu S. Kargbo, Chia-Ling Yu, Daniel Gibney, Jan-Niklas Boyn and Courtney C. Roberts

Emerging climate impact on carbon sinks in a consolidated carbon budget pp. 98-103

Pierre Friedlingstein, Corinne Le Quéré, Michael O’Sullivan, Judith Hauck, Peter Landschützer, Ingrid T. Luijkx, Hongmei Li, Auke van der Woude, Clemens Schwingshackl, Julia Pongratz, Pierre Regnier, Robbie M. Andrew, Dorothee C. E. Bakker, Josep G. Canadell, Philippe Ciais, Thomas Gasser, Matthew W. Jones, Xin Lan, Eric Morgan, Are Olsen, Glen P. Peters, Wouter Peters, Stephen Sitch and Hanqin Tian

Energy flows reveal declining ecosystem functions by animals across Africa pp. 104-112

Ty Loft, Imma Oliveras Menor, Nicola Stevens, Robert Beyer, Hayley S. Clements, Luca Santini, Seth Thomas, Joseph A. Tobias and Yadvinder Malhi

A place-based assessment of biodiversity intactness in sub-Saharan Africa pp. 113-121

Hayley S. Clements, Reinette Biggs, Alta De Vos, Emmanuel Do Linh San, Gareth P. Hempson, Birthe Linden, Bryan Maritz, Ara Monadjem, Chevonne Reynolds, Frances Siebert, Nicola Stevens, Matthew Child, Enrico Di Minin, Karen J. Esler, Maike Hamann, Ty Loft, Belinda Reyers, Odirilwe Selomane, Geethen Singh and Andrew L. Skowno

Neuroendocrine control of calcium mobilization in the fruit fly pp. 122-130

Naoki Okamoto, Yosuke Mizuno, Akira Watanabe, Hiroshi Kohsaka and Ryusuke Niwa

A pangenome and pantranscriptome of hexaploid oat pp. 131-139

Raz Avni, Nadia Kamal, Lidija Bitz, Eric N. Jellen, Wubishet A. Bekele, Tefera T. Angessa, Petri Auvinen, Oliver Bitz, Brian Boyle, Francisco J. Canales, Craig H. Carlson, Brett Chapman, Harmeet Singh Chawla, Yutang Chen, Dario Copetti, Samara Correia de Lemos, Viet Dang, Steven R. Eichten, Kathy Esvelt Klos, Amit M. Fenn, Anne Fiebig, Yong-Bi Fu, Heidrun Gundlach, Rajeev Gupta, Georg Haberer, Tianhua He, Matthias H. Herrmann, Axel Himmelbach, Catherine J. Howarth, Haifei Hu, Julio Isidro y Sánchez, Asuka Itaya, Jean-Luc Jannink, Yong Jia, Rajvinder Kaur, Manuela Knauft, Tim Langdon, Thomas Lux, Sofia Marmon, Vanda Marosi, Klaus F. X. Mayer, Steve Michel, Raja Sekhar Nandety, Kirby T. Nilsen, Edyta Paczos-Grzęda, Asher Pasha, Elena Prats, Nicholas J. Provart, Adriana Ravagnani, Robert W. Reid, Jessica A. Schlueter, Alan H. Schulman, Taner Z. Sen, Jaswinder Singh, Mehtab Singh, Nick Sirijovski, Nils Stein, Bruno Studer, Sirja Viitala, Shauna Vronces, Sean Walkowiak, Penghao Wang, Amanda J. Waters, Charlene P. Wight, Weikai Yan, Eric Yao, Xiao-Qi Zhang, Gaofeng Zhou, Zhou Zhou, Nicholas A. Tinker, Jason D. Fiedler, Chengdao Li, Peter J. Maughan, Manuel Spannagl and Martin Mascher

Shared and language-specific phonological processing in the human temporal lobe pp. 140-151

Ilina Bhaya-Grossman, Matthew K. Leonard, Yizhen Zhang, Laura Gwilliams, Keith Johnson, Junfeng Lu and Edward F. Chang

Genetic elements promote retention of extrachromosomal DNA in cancer cells pp. 152-160

Venkat Sankar, King L. Hung, Aditi Gnanasekar, Ivy Tsz-Lo Wong, Quanming Shi, Katerina Kraft, Matthew G. Jones, Britney Jiayu He, Xiaowei Yan, Julia A. Belk, Kevin J. Liu, Sangya Agarwal, Sean K. Wang, Anton G. Henssen, Paul S. Mischel and Howard Y. Chang

Modelling late gastrulation in stem cell-derived monkey embryo models pp. 161-172

Jie Li, Jie Li, Jing Cao, ShenShen Shang, Liansheng Zhang, Fei Gao, Jiqiang Fu, Hongyu Chen, Guizhong Cui, Haoyuan Wu, Xiaolong Wang, Alfonso Martinez-Arias, Qiang Sun and Zhen Liu

Multiple LDLR family members act as entry receptors for yellow fever virus pp. 173-182

Zhenlu Chong, Sean Hui, Xueer Qiu, Sathvik Palakurty, Alan Sariol, Tomasz Kaszuba, Michael N. Nguyen, Pengfei Li, Saravanan Raju, Paige D. Hall, Christopher A. Nelson, Israel Baltazar-Perez, David A. Price, Paul W. Rothlauf, James E. Crowe, Sean P. J. Whelan, Daisy W. Leung, Gaya K. Amarasinghe, Adam L. Bailey, Daved H. Fremont and Michael S. Diamond

Atomically accurate de novo design of antibodies with RFdiffusion pp. 183-193

Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte, Andrew J. Borst, DéJenaé L. See, Connor Weidle, Riti Biswas, Yutong Yu, Ellen L. Shrock, Russell Ault, Philip J. Y. Leung, Buwei Huang, Inna Goreshnik, John Tam, Kenneth D. Carr, Benedikt Singer, Cameron Criswell, Basile I. M. Wicky, Dionne Vafeados, Mariana Garcia Sanchez, Ho Min Kim, Susana Vázquez Torres, Sidney Chan, Shirley M. Sun, Timothy T. Spear, Yi Sun, Keelan O’Reilly, John M. Maris, Nikolaos G. Sgourakis, Roman A. Melnyk, Chang C. Liu and David Baker

Inhibitory PD-1 axis maintains high-avidity stem-like CD8+ T cells pp. 194-204

Jyh Liang Hor, Edward C. Schrom, Abigail Wong-Rolle, Luke Vistain, Wanjing Shang, Qiang Dong, Chen Zhao, Chengcheng Jin and Ronald N. Germain

NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers pp. 205-215

Jinho Jeong, Simone Hausmann, Hanyang Dong, Kacper Szczepski, Natasha M. Flores, Andy Garcia Gonzalez, Liyang Shi, Xiaoyin Lu, Joanna Lempiäinen, Moritz Jakab, Liyong Zeng, Tourkian Chasan, Eric Bareke, Rui Dong, Emma Carlson, Reinnier Padilla, Dylan Husmann, Julia Thompson, Gerry A. Shipman, Emily Zahn, Courtney A. Barnes, Laiba F. Khan, Liz Marie Albertorio-Sáez, Eva Brill, Vishnu Udayakumar Sunita Kumary, Matthew R. Marunde, Danielle N. Maryanski, Cheryl C. Szany, Bryan J. Venters, Carolina Lin Windham, Michal Eligiusz Nowakowski, Iwona Czaban, Mariusz Jaremko, Michael-Christopher Keogh, Kang Le, Michael J. Soth, Benjamin A. Garcia, Łukasz Jaremko, Jacek Majewski, Pawel K. Mazur and Or Gozani

NSD2 targeting reverses plasticity and drug resistance in prostate cancer pp. 216-226

Jia J. Li, Alessandro Vasciaveo, Dimitris Karagiannis, Zhen Sun, Kristjan H. Gretarsson, Xiao Chen, Ouathek Ouerfelli, Fabio Socciarelli, Ziv Frankenstein, Hanyang Dong, Min Zou, Wei Yuan, Guangli Yang, Gabriel M. Aizenman, Tania Pannellini, Xinjing Xu, Himisha Beltran, Yu Chen, Kevin Gardner, Brian D. Robinson, Johann de Bono, Or Gozani, Cory Abate-Shen, Mark A. Rubin, Massimo Loda, Charles L. Sawyers, Andrea Califano, Chao Lu and Michael M. Shen

Secretome translation shaped by lysosomes and lunapark-marked ER junctions pp. 227-236

Heejun Choi, Ya-Cheng Liao, Young J. Yoon, Jonathan Grimm, Nan Wang, Luke D. Lavis, Robert H. Singer and Jennifer Lippincott-Schwartz

Computational enzyme design by catalytic motif scaffolding pp. 237-245

Markus Braun, Adrian Tripp, Morakot Chakatok, Sigrid Kaltenbrunner, Celina Fischer, David Stoll, Aleksandar Bijelic, Wael Elaily, Massimo G. Totaro, Melanie Moser, Shlomo Y. Hoch, Horst Lechner, Federico Rossi, Matteo Aleotti, Mélanie Hall and Gustav Oberdorfer

Computational design of metallohydrolases pp. 246-253

Donghyo Kim, Seth M. Woodbury, Woody Ahern, Doug Tischer, Alex Kang, Emily Joyce, Asim K. Bera, Nikita Hanikel, Saman Salike, Rohith Krishna, Jason Yim, Samuel J. Pellock, Anna Lauko, Indrek Kalvet, Donald Hilvert and David Baker

2025, volume 648, articles 8094

Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors pp. E12-E13

Nobutaka Kato, Eamon Comer, Tomoyo Sakata-Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. Brancucci, Joshua A. Bittker, Victoria Corey, David Clarke, Emily R. Derbyshire, Gillian L. Dornan, Sandra Duffy, Sean Eckley, Maurice A. Itoe, Karin M. J. Koolen, Timothy A. Lewis, Ping S. Lui, Amanda K. Lukens, Emily Lund, Sandra March, Elamaran Meibalan, Bennett C. Meier, Jacob A. McPhail, Branko Mitasev, Eli L. Moss, Morgane Sayes, Yvonne Van Gessel, Mathias J. Wawer, Takashi Yoshinaga, Anne-Marie Zeeman, Vicky M. Avery, Sangeeta N. Bhatia, John E. Burke, Flaminia Catteruccia, Jon C. Clardy, Paul A. Clemons, Koen J. Dechering, Jeremy R. Duvall, Michael A. Foley, Fabian Gusovsky, Clemens H. M. Kocken, Matthias Marti, Marshall L. Morningstar, Benito Munoz, Daniel E. Neafsey, Amit Sharma, Elizabeth A. Winzeler, Dyann F. Wirth, Christina A. Scherer and Stuart L. Schreiber

Author Correction: Evidence for improved DNA repair in the long-lived bowhead whale pp. E14-E14

Denis Firsanov, Max Zacher, Xiao Tian, Todd L. Sformo, Yang Zhao, Gregory Tombline, J. Yuyang Lu, Zhizhong Zheng, Luigi Perelli, Enrico Gurreri, Li Zhang, Jing Guo, Anatoly Korotkov, Valentin Volobaev, Seyed Ali Biashad, Zhihui Zhang, Johanna Heid, Alexander Y. Maslov, Shixiang Sun, Zhuoer Wu, Jonathan Gigas, Eric C. Hillpot, John C. Martinez, Minseon Lee, Alyssa Williams, Abbey Gilman, Nicholas Hamilton, Ekaterina Strelkova, Ena Haseljic, Avnee Patel, Maggie E. Straight, Nalani Miller, Julia Ablaeva, Lok Ming Tam, Chloé Couderc, Michael R. Hoopmann, Robert L. Moritz, Shingo Fujii, Amandine Pelletier, Dan J. Hayman, Hongrui Liu, Yuxuan Cai, Anthony K. L. Leung, Zhengdong Zhang, C. Bradley Nelson, Lisa M. Abegglen, Joshua D. Schiffman, Vadim N. Gladyshev, Carlo C. Maley, Mauro Modesti, Giannicola Genovese, Mirre J. P. Simons, Jan Vijg, Andrei Seluanov and Vera Gorbunova

Author Correction: The first-principles phase diagram of monolayer nanoconfined water pp. E15-E15

Venkat Kapil, Christoph Schran, Andrea Zen, Ji Chen, Chris J. Pickard and Angelos Michaelides

Author Correction: Video‐rate tunable colour electronic paper with human resolution pp. E16-E16

Ade Satria Saloka Santosa, Yu-Wei Chang, Andreas B. Dahlin, Lars Österlund, Giovanni Volpe and Kunli Xiong

Author Correction: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis pp. E17-E17

Kim Newton, Katherine E. Wickliffe, Debra L. Dugger, Allie Maltzman, Merone Roose-Girma, Monika Dohse, László Kőműves, Joshua D. Webster and Vishva M. Dixit

Author Correction: Seismic detection of a 600-km solid inner core in Mars pp. E18-E18

Huixing Bi, Daoyuan Sun, Ningyu Sun, Zhu Mao, Mingwei Dai and Douglas Hemingway

Editorial Expression of Concern: Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells pp. E19-E19

Takeshi Fujiwara, Madhavi Bandi, Masayuki Nitta, Elena V. Ivanova, Roderick T. Bronson and David Pellman

How my institution strengthened research despite chronic underfunding pp. 500-500

Anil Shanker

The best science images of 2025 — Nature’s picks pp. 508-513

Emma Stoye and Fred Schwaller

The top US health director who stood up for science — and was fired pp. 516-517

Max Kozlov

This science sleuth revealed a retraction crisis at Indian universities pp. 518-518

Miryam Naddaf

The visionary physicist who gave us a new way to view the cosmos pp. 519-519

Davide Castelvecchi

The first global pandemic treaty — and the woman who made it happen pp. 520-521

Celeste Biever

‘Giant step forward’ for Huntington’s — the scientist behind the first gene therapy pp. 522-522

Elie Dolgin

9,000 metres under the sea: this researcher found the deepest animal ecosystems on Earth pp. 523-523

Rachel Fieldhouse

This scientist is breeding billions of mosquitoes to fight disease in Brazil pp. 524-525

Mariana Lenharo

The Chinese finance whizz whose DeepSeek AI model stunned the world pp. 526-526

Elizabeth Gibney

This scientist found a new trick of the immune system by digging through cellular rubbish pp. 527-527

Cassandra Willyard

The baby whose life was saved by the first personalized CRISPR therapy pp. 528-529

Heidi Ledford

Grant cuts, arrests, lay-offs: Trump made 2025 a tumultuous year for science pp. 530-531

Jeff Tollefson

In praise of inefficiency, failure and friendship: ten galvanizing reads for this festive season pp. 532-534

Kelly-Ann Allen, Tara McAllister, Yamini Aiyar, Sirry Alang, Misa Shimuta, Elma Kay, Mohamed Ibrahim, Mariana Viglino, Séverine Toussaert and Nick Lane

AI is transforming the economy — understanding its impact requires both data and imagination pp. 535-537

Daniel Björkegren

Weighing up the wild-meat harvest in Amazonia pp. 543-544

Carla Morsello and Patricia Carignano Torres

Solar cells that combine multiple perovskite layers surpass 30% efficiency pp. 544-546

Shuaifeng Hu and Henry J. Snaith

Mystery owner of African hominin foot identified pp. 546-548

Fred Spoor

Ancient DNA offers clues about mysterious prehistoric settlement in China pp. 548-549

Yu Dong and Ripan S. Malhi

Experiments reveal extreme water generation during planet formation pp. 551-555

F. Miozzi, A. Shahar, E. D. Young, J. Wang, A. Steele, S. Borensztajn, S. M. Vitale, E. S. Bullock, N. Wehr and J. Badro

Titan’s strong tidal dissipation precludes a subsurface ocean pp. 556-561

Flavio Petricca, Steven D. Vance, Marzia Parisi, Dustin Buccino, Gael Cascioli, Julie Castillo-Rogez, Brynna G. Downey, Francis Nimmo, Gabriel Tobie, Baptiste Journaux, Andrea Magnanini, Ula Jones, Mark Panning, Amirhossein Bagheri, Antonio Genova and Jonathan I. Lunine

Laser spectroscopy and CP-violation sensitivity of actinium monofluoride pp. 562-568

M. Athanasakis-Kaklamanakis, M. Au, A. Kyuberis, C. Zülch, K. Gaul, H. Wibowo, L. Skripnikov, L. Lalanne, J. R. Reilly, Á. Koszorús, S. Bara, J. Ballof, R. Berger, C. Bernerd, A. Borschevsky, A. A. Breier, K. Chrysalidis, T. E. Cocolios, R. P. de Groote, A. Dorne, J. Dobaczewski, C. M. Fajardo Zambrano, K. T. Flanagan, S. Franchoo, J. D. Johnson, R. F. Garcia Ruiz, D. Hanstorp, S. Kujanpää, Y. C. Liu, K. M. Lynch, A. McGlone, N. S. Mosyagin, G. Neyens, M. Nichols, L. Nies, F. Pastrana, S. Rothe, W. Ryssens, B. van den Borne, J. Wessolek, S. G. Wilkins and X. F. Yang

An 11-qubit atom processor in silicon pp. 569-575

Hermann Edlbauer, Junliang Wang, A. M. Saffat-Ee Huq, Ian Thorvaldson, Michael T. Jones, Saiful Haque Misha, William J. Pappas, Christian M. Moehle, Yu-Ling Hsueh, Henric Bornemann, Samuel K. Gorman, Yousun Chung, Joris G. Keizer, Ludwik Kranz and Michelle Y. Simmons

Programmable 200 GOPS Hopfield-inspired photonic Ising machine pp. 576-584

Nayem Al-Kayed, Charles St-Arnault, Hugh Morison, A. Aadhi, Chaoran Huang, Alexander N. Tait, David V. Plant and Bhavin J. Shastri

Visualizing interaction-driven restructuring of quantum Hall edge states pp. 585-590

Jiachen Yu, Haotan Han, Kristina G. Wolinski, Ruihua Fan, Amir S. Mohammadi, Tianle Wang, Taige Wang, Liam Cohen, Kenji Watanabe, Takashi Taniguchi, Andrea F. Young, Michael P. Zaletel and Ali Yazdani

3D nanolithography with metalens arrays and spatially adaptive illumination pp. 591-599

Songyun Gu, Chenkai Mao, Anna Guell Izard, Sarvesh Sadana, Dongping Terrel-Perez, Magi Mettry-Yassa, Wonjin Choi, Wenjie Zhou, Hujie Yan, Ziran Zhou, Travis Massey, Alex Abelson, You Zhou, Sijia Huang, Chiara Daraio, Thejaswi Umanath Tumkur, Jonathan A. Fan and Xiaoxing Xia

All-perovskite tandem solar cells with dipolar passivation pp. 600-606

Renxing Lin, Han Gao, Jing Lou, Jian Xu, Mengran Yin, Pu Wu, Chenshuaiyu Liu, Yijia Guo, Enzuo Wang, Shuncheng Yang, Runnan Liu, Dong Zhou, Changzeng Ding, Anh Dinh Bui, Ni Yin, Daniel H. Macdonald, Chang-Qi Ma, Qi Chen, Ke Xiao, Xin Luo, Ye Liu, Ludong Li, Yongxi Li, Chao Chang and Hairen Tan

Selective methylene oxidation in α,β-unsaturated carbonyl natural products pp. 607-615

Chiyoung Ahn, Alexander Gomez, Marc A. Hartmann and M. Christina White

The global hydrogen budget pp. 616-624

Zutao Ouyang, Robert B. Jackson, Marielle Saunois, Josep G. Canadell, Yuanhong Zhao, Catherine Morfopoulos, Paul B. Krummel, Prabir K. Patra, Glen P. Peters, Fraser Dennison, Thomas Gasser, Alexander T. Archibald, Vivek Arora, Gabriel Baudoin, Naveen Chandra, Philippe Ciais, Steven J. Davis, Sarah Feron, Fangzhou Guo, Didier Hauglustaine, Christopher D. Jones, Matthew W. Jones, Etsushi Kato, Daniel Kennedy, Jürgen Knauer, Sebastian Lienert, Danica Lombardozzi, Joe R. Melton, Julia E.M.S. Nabel, Michael O’Sullivan, Gabrielle Pétron, Benjamin Poulter, Joeri Rogelj, David Sandoval Calle, Pete Smith, Parvadha Suntharalingam, Hanqin Tian, Chenghao Wang and Andy Wiltshire

Healthy forests safeguard traditional wild meat food systems in Amazonia pp. 625-633

André Pinassi Antunes, Pedro de Araujo Lima Constantino, Julia E. Fa, Daniel P. Munari, Thais Q. Morcatty, Michelle C. M. Jacob, Bruce W. Nelson, Mariana Franco Cassino, Elildo A. R. Carvalho, Amy Ickowitz, Lauren Coad, Richard E. Bodmer, Pedro Mayor, Cecile Richard-Hansen, João Valsecchi, João V. Campos-Silva, Juarez C. B. Pezzuti, Miguel Aparício, Eduardo M. von Muhlen, Marcela Alvares Oliveira, Milton J. de Paula, Natalia C. Pimenta, Marina A. R. de Mattos Vieira, Marcelo A. Santos Junior, André V. Nunes, Jean P. Boubli, Luan M. G. Suruí, Eneias C. S. Paumari, Abimael V. C. Paumari, José Lino V. S. Paumari, Germano C. Paumari, Ana Paula L. R. Katukina, Dzoodzo Baniwa, Valencio S. M. Baniwa, Walter S. L. Baniwa, Abel O. F. Baniwa, Armindo B. Baniwa, Isaías J. S. Baniwa, Yaukuma Waura, Jairo Silvestre Apurinã, Valdir S. S. Apurinã, Josiane O. G. Tikuna, Elias P. A. L. Tikuna, José L. Kaxinauá, Kussugi B. Kuikuro, Jorge T. Penaforth Kaixana, George H. Rebelo, Dione Torquato, Vanessa S. F. Apurinã, Miguel Antúnez, Pedro E. Perez-Peña, Tula G. Fang, Pablo E. Puertas, Rolando M. Aquino, Louise Maranhão, Guillaume Longin, Cíntia K. M. Lopes and Hani R. El Bizri

A long-necked early dinosaur from a newly discovered Upper Triassic basin in the Andes pp. 634-639

E. Martín Hechenleitner, Agustín G. Martinelli, Sebastián Rocher, Lucas E. Fiorelli, Malena Juarez, Jeremías R. A. Taborda and Julia B. Desojo

New finds shed light on diet and locomotion in Australopithecus deyiremeda pp. 640-648

Yohannes Haile-Selassie, Gary T. Schwartz, Thomas C. Prang, Beverly Z. Saylor, Alan Deino, Luis Gibert, Anna Ragni and Naomi E. Levin

From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes pp. 649-658

Victor Loegler, Pia Thiele, Elie Teyssonnière, Andreas Tsouris, Gauthier Brach, Corinne Cruaud, Emilie Payen, Stefan Engelen, Maitreya J. Dunham, Jing Hou, Anne Friedrich and Joseph Schacherer

Ancient DNA from Shimao city records kinship practices in Neolithic China pp. 659-667

Zehui Chen, Jacob D. Gardner, Zhouyong Sun, E. Andrew Bennett, Qian Han, Xuesong Pei, Jing Shao, Han Shi, Wenjun Wang, Jiayang Xue, Fan Bai, Xiangming Dai, Nu He, Xiaoning Guo, Nan Di, Xiaowei Mao, Tianxiang Liu, Peng Cao, Feng Liu, Qingyan Dai, Xiaotian Feng, Wanjing Ping, Xiaohong Wu, Lizhao Zhang, Liang Chen and Qiaomei Fu

Sensory expectations shape neural population dynamics in motor circuits pp. 668-677

Jonathan A. Michaels, Mehrdad Kashefi, Jack Zheng, Olivier Codol, Jeffrey Weiler, Rhonda Kersten, Jonathan C. Lau, Paul L. Gribble, Jörn Diedrichsen and J. Andrew Pruszynski

A probabilistic histological atlas of the human brain for MRI segmentation pp. 678-685

Adrià Casamitjana, Matteo Mancini, Eleanor Robinson, Loïc Peter, Roberto Annunziata, Juri Althonayan, Shauna Crampsie, Emily Blackburn, Benjamin Billot, Alessia Atzeni, Oula Puonti, Yaël Balbastre, Peter Schmidt, James Hughes, Jean C. Augustinack, Brian L. Edlow, Lilla Zöllei, David L. Thomas, Dorit Kliemann, Martina Bocchetta, Catherine Strand, Janice L. Holton, Zane Jaunmuktane and Juan Eugenio Iglesias

Florigen activation complex forms via multifaceted assembly in Arabidopsis pp. 686-695

He Gao, Na Ding, Yuang Wu, Dongli Yu, Shi-Zhao Zhou, Sara Christina Stolze, Coral Vincent, Gabriel Rodríguez Maroto, Pedro de los Reyes, Anne Harzen, Martina Cerise, Vítor da Silveira Falavigna, Ertong Li, Ton Timmers, Ulla Neumann, Hirofumi Nakagami, Jin-Yong Hu, Jijie Chai and George Coupland

Multi-omic profiling reveals age-related immune dynamics in healthy adults pp. 696-706

Qiuyu Gong, Mehul Sharma, Marla C. Glass, Emma L. Kuan, Aishwarya Chander, Mansi Singh, Lucas T. Graybuck, Zachary J. Thomson, Christian M. LaFrance, Samir Rachid Zaim, Tao Peng, Lauren Y. Okada, Palak C. Genge, Katherine E. Henderson, Elisabeth M. Dornisch, Erik D. Layton, Peter J. Wittig, Alexander T. Heubeck, Nelson M. Mukuka, Julian Reading, Garrett Strawn, Teminijesu Titus-Adewunmi, Kathleen Abadie, Charles R. Roll, Veronica Hernandez, Vaishnavi Parthasarathy, Tyanna J. Stuckey, Blessing Musgrove, Elliott Swanson, Cara Lord, Morgan D. A. Weiss, Cole G. Phalen, Regina R. Mettey, Kevin J. Lee, John B. Johanneson, Erin K. Kawelo, Jessica Garber, Upaasana Krishnan, Megan Smithmyer, E. John Wherry, Laura A. Vella, Sarah E. Henrickson, Mackenzie S. Kopp, Adam K. Savage, Lynne A. Becker, Paul Meijer, Ernest M. Coffey, Jorg J. Goronzy, Mikael Sigvardsson, Cate Speake, Thomas F. Bumol, Ananda W. Goldrath, Troy R. Torgerson, Xiao-jun Li, Peter J. Skene, Jane H. Buckner and Claire E. Gustafson

Host cell Z-RNAs activate ZBP1 during virus infections pp. 707-716

Chaoran Yin, Aleksandr Fedorov, Hongyan Guo, Jeremy Chase Crawford, Claire Rousseau, Xiao Zhong, Riley M. Williams, Avishekh Gautam, Heather S. Koehler, Adam W. Whisnant, Thomas Hennig, Anna Rozina, Yuhan Zhong, Shuangjuan Lv, Valter Bergant, Shuqi Wang, Peter Dröge, Sven Miller, Maria Poptsova, Jan Rehwinkel, Andreas Pichlmair, Edward S. Mocarski, Paul G. Thomas, Lars Dölken, Ting Zhang, Alan Herbert and Siddharth Balachandran

Evidence for improved DNA repair in the long-lived bowhead whale pp. 717-725

Denis Firsanov, Max Zacher, Xiao Tian, Todd L. Sformo, Yang Zhao, Gregory Tombline, J. Yuyang Lu, Zhizhong Zheng, Luigi Perelli, Enrico Gurreri, Li Zhang, Jing Guo, Anatoly Korotkov, Valentin Volobaev, Seyed Ali Biashad, Zhihui Zhang, Johanna Heid, Alexander Y. Maslov, Shixiang Sun, Zhuoer Wu, Jonathan Gigas, Eric C. Hillpot, John C. Martinez, Minseon Lee, Alyssa Williams, Abbey Gilman, Nicholas Hamilton, Ekaterina Strelkova, Ena Haseljic, Avnee Patel, Maggie E. Straight, Nalani Miller, Julia Ablaeva, Lok Ming Tam, Chloé Couderc, Michael R. Hoopmann, Robert L. Moritz, Shingo Fujii, Amandine Pelletier, Dan J. Hayman, Hongrui Liu, Yuxuan Cai, Anthony K. L. Leung, Zhengdong Zhang, C. Bradley Nelson, Lisa M. Abegglen, Joshua D. Schiffman, Vadim N. Gladyshev, Carlo C. Maley, Mauro Modesti, Giannicola Genovese, Mirre J. P. Simons, Jan Vijg, Andrei Seluanov and Vera Gorbunova

Neoadjuvant immunotherapy in mismatch-repair-proficient colon cancers pp. 726-735

Pedro B. Tan, Yara L. Verschoor, José G. van den Berg, Sara Balduzzi, Niels F. M. Kok, Marieke E. Ijsselsteijn, Kat Moore, Adham Jurdi, Antony Tin, Paulien Kaptein, Monique E. van Leerdam, John B. A. G. Haanen, Emile E. Voest, Noel F. C. C. de Miranda, Ton N. Schumacher, Lodewyk F. A. Wessels and Myriam Chalabi

Anti-progestin therapy targets hallmarks of breast cancer risk pp. 736-745

Bruno M. Simões, Robert Pedley, Curtis W. McCloskey, Matthew Roberts, Austin D. Reed, Alecia-Jane Twigger, Pirashaanthy Tharmapalan, Amanda Caruso, Sara Cabral, Anthony J. Wilby, Hannah Harrison, Yuxi Zhou, Alice Greenhalgh, Suad A. Alghamdi, Martina Forestiero, Jesica Lopez-Muñoz, Jasmin Roche, Ren Jie Tuieng, Muhammad A. Khan, Steven Squires, Susan M. Astley, Elaine F. Harkness, Angélica Santiago-Gómez, Katherine Spence, Jessica Ritchie, Susan Pritchard, Yit Lim, Michael J. Sherratt, Sebastiano Andò, Anthony Howell, D. Gareth Evans, Andrew P. Gilmore, Walid T. Khaled, Rama Khokha, Robert B. Clarke and Sacha J. Howell

Helicase-mediated mechanism of SSU processome maturation and disassembly pp. 746-754

Olga Buzovetsky and Sebastian Klinge

Structural snapshots capture nucleotide release at the μ-opioid receptor pp. 755-763

Saif Khan, Aaliyah S. Tyson, Mohsen Ranjbar, Zixin Zhang, Jaskaran Singh, Gye Won Han and Cornelius Gati

Retraction Note: The economic commitment of climate change pp. 764-764

Maximilian Kotz, Anders Levermann and Leonie Wenz

Waste not: how researchers harness pee and poo for science pp. 765-767

Hannah Docter-Loeb

Giving a voice to animals: Laos’s national herpetologist on her day-to-day pp. 770-770

Dave Tacon

2025, volume 648, articles 8093

Author Correction: A pangenome and pantranscriptome of hexaploid oat pp. E5-E5

Raz Avni, Nadia Kamal, Lidija Bitz, Eric N. Jellen, Wubishet A. Bekele, Tefera T. Angessa, Petri Auvinen, Oliver Bitz, Brian Boyle, Francisco J. Canales, Craig H. Carlson, Brett Chapman, Harmeet Singh Chawla, Yutang Chen, Dario Copetti, Samara Correia de Lemos, Viet Dang, Steven R. Eichten, Kathy Esvelt Klos, Amit M. Fenn, Anne Fiebig, Yong-Bi Fu, Heidrun Gundlach, Rajeev Gupta, Georg Haberer, Tianhua He, Matthias H. Herrmann, Axel Himmelbach, Catherine J. Howarth, Haifei Hu, Julio Isidro y Sánchez, Asuka Itaya, Jean-Luc Jannink, Yong Jia, Rajvinder Kaur, Manuela Knauft, Tim Langdon, Thomas Lux, Sofia Marmon, Vanda Marosi, Klaus F. X. Mayer, Steve Michel, Raja Sekhar Nandety, Kirby T. Nilsen, Edyta Paczos-Grzęda, Asher Pasha, Elena Prats, Nicholas J. Provart, Adriana Ravagnani, Robert W. Reid, Jessica A. Schlueter, Alan H. Schulman, Taner Z. Sen, Jaswinder Singh, Mehtab Singh, Nick Sirijovski, Nils Stein, Bruno Studer, Sirja Viitala, Shauna Vronces, Sean Walkowiak, Penghao Wang, Amanda J. Waters, Charlene P. Wight, Weikai Yan, Eric Yao, Xiao-Qi Zhang, Gaofeng Zhou, Zhou Zhou, Nicholas A. Tinker, Jason D. Fiedler, Chengdao Li, Peter J. Maughan, Manuel Spannagl and Martin Mascher

Author Correction: An asymmetric fission island driven by shell effects in light fragments pp. E6-E6

P. Morfouace, J. Taieb, A. Chatillon, L. Audouin, G. Blanchon, R. N. Bernard, N. Dubray, N. Pillet, D. Regnier, H. Alvarez-Pol, F. Amjad, P. André, G. Authelet, L. Atar, T. Aumann, J. Benlliure, K. Boretzky, L. Bott, T. Brecelj, C. Caesar, P. Carpentier, E. Casarejos, J. Cederkäll, A. Corsi, D. Cortina-Gil, A. Cvetinović, E. De Filippo, T. Dickel, M. Feijoo, L. M. Fonseca, D. Galaviz, G. García-Jiménez, I. Gasparic, E. I. Geraci, R. Gernhäuser, B. Gnoffo, K. Göbel, A. Graña-González, E. Haettner, A.-L. Hartig, M. Heil, A. Heinz, T. Hensel, M. Holl, C. Hornung, A. Horvat, A. Jedele, D. Jelavic Malenica, T. Jenegger, L. Ji, H. T. Johansson, B. Jonson, B. Jurado, N. Kalantar-Nayestanaki, E. Kazantseva, A. Kelic-Heil, O. A. Kiselev, P. Klenze, R. Knöbel, D. Körper, D. Kostyleva, T. Kröll, N. Kuzminchuk, B. Laurent, I. Lihtar, Yu. A. Litvinov, B. Löher, N. S. Martorana, B. Mauss, S. Murillo Morales, D. Mücher, I. Mukha, E. Nacher, A. Obertelli, E. V. Pagano, V. Panin, J. Park, S. Paschalis, M. Petri, S. Pietri, S. Pirrone, G. Politi, L. Ponnath, A. Revel, H.-B. Rhee, J. L. Rodríguez-Sánchez, L. Rose, D. Rossi, P. Roy, P. Russotto, C. Scheidenberger, H. Scheit, H. Simon, S. Storck-Dutine, A. Stott, Y. L. Sun, C. Sürder, Y. K. Tanaka, R. Taniuchi, O. Tengblad, I. Tisma, H. T. Törnqvist, M. Trimarchi, S. Velardita, J. Vesic, B. Voss, F. Wamers, H. Weick, F. Wienholtz, J. Zhao and M. Zhukov

Author Correction: Spatial fibroblast niches define Crohn’s fistulae pp. E7-E7

Colleen McGregor, Xiao Qin, Marta Jagielowicz, Tarun Gupta, Zinan Yin, Verena Lentsch, David Fawkner-Corbett, Vy Wien Lai, Paula Gomez Castro, Esther Bridges, Chloe Hyun-Jung Lee, Huei-Wen Chuang, Lei Deng, Anna Aulicino, Renuka Teague, Sorayya Moradi, Jun Sung Park, Jeongmin Woo, Kexin Xu, Ruchi Tandon, Nicole Cianci, Jan Bornschein, Ling-Pei Ho, Paulina Siejka-Zielinska, Zoe Christoforidou, Sarah Hill, Johannes Lehmann, Rhea Kujawa, Paola Vargas Gutierrez, Carol Cheng, Maria Greco, Katherine Baker, Mark Bignell, Bruce George, Eve Fryer, Michael Vieth, Agne Antanaviciute and Alison Simmons

Author Correction: Photocatalytic low-temperature defluorination of PFASs pp. E8-E8

Hao Zhang, Jin-Xiang Chen, Jian-Ping Qu and Yan-Biao Kang

Author Correction: Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver pp. E9-E9

Weiguo Fan, Kolade Adebowale, Lóránd Váncza, Yuan Li, Md Foysal Rabbi, Koshi Kunimoto, Dongning Chen, Gergely Mozes, David Kung-Chun Chiu, Yisi Li, Junyan Tao, Yi Wei, Nia Adeniji, Ryan L. Brunsing, Renumathy Dhanasekaran, Aatur Singhi, David Geller, Su Hao Lo, Louis Hodgson, Edgar G. Engleman, Gregory W. Charville, Vivek Charu, Satdarshan P. Monga, Taeyoon Kim, Rebecca G. Wells, Ovijit Chaudhuri and Natalie J. Török

Author Correction: Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants pp. E10-E10

Zhiqiang Ku, Xuping Xie, Paul R. Hinton, Xinli Liu, Xiaohua Ye, Antonio E. Muruato, Dean C. Ng, Sujit Biswas, Jing Zou, Yang Liu, Deepal Pandya, Vineet D. Menachery, Sachi Rahman, Yu-An Cao, Hui Deng, Wei Xiong, Kevin B. Carlin, Junquan Liu, Hang Su, Elizabeth J. Haanes, Bruce A. Keyt, Ningyan Zhang, Stephen F. Carroll, Pei-Yong Shi and Zhiqiang An

Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury pp. E11-E11

Nobuhiko Kayagaki, Irma B. Stowe, Kamela Alegre, Ishan Deshpande, Shuang Wu, Zhonghua Lin, Opher S. Kornfeld, Bettina L. Lee, Juan Zhang, John Liu, Eric Suto, Wyne P. Lee, Kellen Schneider, WeiYu Lin, Dhaya Seshasayee, Tushar Bhangale, Cecile Chalouni, Matthew C. Johnson, Prajakta Joshi, Jan Mossemann, Sarah Zhao, Danish Ali, Neil M. Goldenberg, Blayne A. Sayed, Benjamin E. Steinberg, Kim Newton, Joshua D. Webster, Ryan L. Kelly and Vishva M. Dixit

Glimmers of hope for a deadly disease pp. S47-S47

Shraddha Chakradhar

Exposing a silent cancer pp. S48-S48

Rachel Nuwer

Pancreatic cancer is evasive. Is the nervous system the reason why? pp. S49-S50

Laura Dattaro

The pancreatic cancer models helping to drive innovation in the field pp. S51-S53

Rachel Nuwer

Early detection could improve pancreatic cancer’s poor survival rates pp. S54-S56

Cassandra Willyard

A breathalyser-style test for detecting pancreatic cancer pp. S57-S57

Esme Hedley

Therapeutic vaccines can challenge pancreatic cancer before it takes hold pp. S58-S60

Anthony King

Six highlights from pancreatic cancer research pp. S61-S62

Laura Vargas-Parada

Will young universities set the pace in the age of AI? pp. S91-S91

Bec Crew

What would an AI university look like and how might it change education? pp. S92-S95

Jackson Ryan

Four young universities share their strategies for success pp. S96-S99

Xiaoying You and Benjamin Plackett

The Indian Ocean disaster is a climate tragedy — and needs more attention pp. 252-252

Dyna Rochmyaningsih

Trump’s AI ‘Genesis Mission’: what are the risks and opportunities? pp. 253-255

Elizabeth Gibney, Alexandra Witze and Jenna Ahart

‘Fire amoeba’ survives in hotter conditions than any other complex cell pp. 255-256

Ewen Callaway

Major AI conference flooded with peer reviews written fully by AI pp. 256-257

Miryam Naddaf

Has the mysterious ‘compass’ organ of birds been found at last? pp. 257-258

Davide Castelvecchi

AlphaFold is five years old — these charts show how it revolutionized science pp. 258-259

Ewen Callaway

This is the world’s largest spider web — November’s best science images pp. 260-260

Fred Schwaller and Katie Kavanagh

Is your brain tired? Researchers are discovering the roots of mental fatigue pp. 262-264

Lynne Peeples

What we eat is making us obese and sick — but science shows solutions are within reach pp. 265-266

Tim Spector

How the Royal Institution made science a seasonal spectacle pp. 267-269

Philip Ball

Of masks and Mayans: Books in brief pp. 269-269

Andrew Robinson

Darleane C. Hoffman obituary: chemist who expanded the periodic table pp. 270-270

Dawn Shaughnessy

Food will be more affordable — if we double funds for agriculture research now pp. 271-274

Philip G. Pardey, Connie Chan-Kang, Gert-Jan Stads, Yuan Chai, Julian M. Alston, Jan Greyling and Hernán Muñoz

How to get science back into policymaking pp. 275-277

Diane Coyle and Michael Kenny

Argentina must finish building the CART radio telescope pp. 278-278

Mariana Orellana

Don’t overlook the value of co-supervision in PhD training pp. 278-278

Kok-Siong Poon and Evelyn Siew-Chuan Koay

Drug woes won’t be tamed by US price regulations pp. 278-278

Richard Xie

Better models are needed to gauge the ecological impacts of reservoirs pp. 278-278

Xingcheng Yan, Sijiu Zhang, Qiuwen Chen and Jianyun Zhang

Extreme rainfall poses the biggest risk to Mumbai’s most vulnerable people pp. 279-280

Subimal Ghosh

Practical alternative to explosive reaction will improve lab safety pp. 280-281

Tim Schulte and Tobias Ritter

T. rex debate settled: contested fossils are smaller rival species, not juveniles pp. 282-283

Lawrence M. Witmer

AI discovers learning algorithm that outperforms those designed by humans pp. 283-285

Joel Lehman

Nuclear clocks could use electrical signals to keep time pp. 285-286

Xiwen Zhang and Olga Kocharovskaya

AI chatbots can persuade voters to change their minds pp. 287-288

Chiara Vargiu and Alessandro Nai

The influence of short-lived halogens on atmospheric chemistry and climate pp. 289-299

Alfonso Saiz-Lopez, Anoop S. Mahajan, Jonathan Abbatt, Nicole Bobrowski, Steven S. Brown, John P. Burrows, Lucy J. Carpenter, Martyn P. Chipperfield, Carlos A. Cuevas, Rafael P. Fernandez, Ryan Hossaini, Douglas E. Kinnison, Jean-Francois Lamarque, Barbara J. Finlayson-Pitts, John M. C. Plane, Ulrich Platt, Kerri A. Pratt, A. R. Ravishankara, Ross J. Salawitch, Eric S. Saltzman, William R. Simpson, Susan Solomon, Joel A. Thornton and Tao Wang

Laser-based conversion electron Mössbauer spectroscopy of 229ThO2 pp. 300-305

Ricky Elwell, James E. S. Terhune, Christian Schneider, Harry W. T. Morgan, Hoang Bao Tran Tan, Udeshika C. Perera, Daniel A. Rehn, Marisa C. Alfonso, Lars von der Wense, Benedict Seiferle, Kevin Scharl, Peter G. Thirolf, Andrei Derevianko and Eric R. Hudson

Discovering state-of-the-art reinforcement learning algorithms pp. 312-319

Junhyuk Oh, Gregory Farquhar, Iurii Kemaev, Dan A. Calian, Matteo Hessel, Luisa Zintgraf, Satinder Singh, Hado van Hasselt and David Silver

Ferroelectric transistors for low-power NAND flash memory pp. 320-326

Sijung Yoo, Taek Jung Kim, Seung-Geol Nam, Donghoon Kim, Kihong Kim, Yunseong Lee, Moonil Jung, Kwang-Hee Lee, Seokhoon Choi, Seung Dam Hyun, Min-Hyun Lee, Seogwoo Hong, Haesung Kim, Ki Deok Bae, Hyangsook Lee, Jung Yeon Won, Dong-Jin Yun, Byeong Gyu Chae, Wook Ghee Hahn, Chang Hyun Joo, Sanghyun Jo, Yoonsang Park, Kyung Mee Song, Kyooho Jung, Suhwan Lim, Kwangyou Seo, Kwangsoo Kim, Wanki Kim, Daewon Ha, Jee-Eun Yang, Seung-Yeul Yang, Sangwook Kim, Jinseong Heo and Duk-Hyun Choe

Quantifying grain boundary deformation mechanisms in small-grained metals pp. 327-332

Romain Gautier, Frédéric Mompiou, Oliver Renk, Christophe Coupeau, Nicolas Combe, Gregory Seine and Marc Legros

Accelerating the discovery of multicatalytic cooperativity pp. 333-340

Marcus H. Sak, Richard Y. Liu, Eugene E. Kwan and Eric N. Jacobsen

Direct deaminative functionalization with N-nitroamines pp. 341-348

Guangliang Tu, Ke Xiao, Xiaoping Chen, Haoran Xu, Haifeng Zeng, Fangjiang Zhang, Xiao-Song Xue and Xiaheng Zhang

Built environment disparities are amplified during extreme weather recovery pp. 349-356

Tianyuan Huang, Chad Zanocco, Zhecheng Wang, Jackelyn Hwang and Ram Rajagopal

Nanotyrannus and Tyrannosaurus coexisted at the close of the Cretaceous pp. 357-367

Lindsay E. Zanno and James G. Napoli

The evolution of facultative symbiosis in stony corals pp. 368-376

Shani Levy, Xavier Grau-Bové, Iana V. Kim, Sebastian R. Najle, Ewa Księżopolska, Anamaria Elek, Laia Montes-Espuña, Sean A. Montgomery, Tali Mass and Arnau Sebé-Pedrós

A global coral phylogeny reveals resilience and vulnerability through deep time pp. 377-382

Claudia Francesca Vaga, Andrea M. Quattrini, Isabela Galvão de Lossio e Seiblitz, Danwei Huang, Zheng Bin Randolph Quek, Jarosław Stolarski, Stephen Douglas Cairns and Marcelo Visentini Kitahara

Origins of chromosome instability unveiled by coupled imaging and genomics pp. 383-393

Marco Raffaele Cosenza, Alice Gaiatto, Büşra Erarslan Uysal, Álvaro Andrades, Nina Luisa Sautter, Marina Simunovic, Michael Adrian Jendrusch, Sonia Zumalave, Tobias Rausch, Aliaksandr Halavatyi, Eva-Maria Geissen, Joshua Lucas Eigenmann, Thomas Weber, Patrick Hasenfeld, Eva Benito, Catherine Stober, Isidro Cortes-Ciriano, Andreas E. Kulozik, Rainer Pepperkok and Jan O. Korbel

Persuading voters using human–artificial intelligence dialogues pp. 394-401

Hause Lin, Gabriela Czarnek, Benjamin Lewis, Joshua P. White, Adam J. Berinsky, Thomas Costello, Gordon Pennycook and David G. Rand

Thiorphan reprograms neurons to promote functional recovery after spinal cord injury pp. 402-408

E. A. van Niekerk, C. Marques de Freria, B. O. Mancarci, K. Groeniger, D. Kulinich, T. Riley, R. Kawaguchi, S. Okawa, T. Vokes, E. S. Rosenzweig, E. Sinopoulou, M. J. Castle, R. Huie, A. R. Ferguson, N. Kfoury-Beaumont, A. Khalessi, P. Pavlidis and M. H. Tuszynski

Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology pp. 409-417

Domenic Burger, Marianna Kashyrina, Lukas van den Heuvel, Hortense de La Seiglière, Amanda J. Lewis, Francesco De Nuccio, Inayathulla Mohammed, Jérémy Verchère, Cécile Feuillie, Mélanie Berbon, Marie-Laure Arotcarena, Aude Retailleau, Erwan Bezard, Marie-Hélène Canron, Wassilios G. Meissner, Antoine Loquet, Luc Bousset, Christel Poujol, K. Peter R. Nilsson, Florent Laferrière, Thierry Baron, Dario Domenico Lofrumento, Francesca De Giorgi, Henning Stahlberg and François Ichas

Transcriptional interferences ensure one olfactory receptor per ant neuron pp. 418-426

Bogdan Sieriebriennikov, Olena Kolumba, Aurore de Beaurepaire, Jennifer Wu, Valentina Fambri, Eva Bardol, Yuwei Zhong, Ildar Gainetdinov, Danny Reinberg, Hua Yan and Claude Desplan

Mortality impacts of rainfall and sea-level rise in a developing megacity pp. 427-433

Tom Bearpark, Ashwin Rode and Archana Patankar

Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis pp. 434-442

Omer Nadel, Rawad Hanna, Andrey Rozenberg, Dror Shitrit, Ran Tahan, Irena Pekarsky, Oded Béjà, Oded Kleifeld and Debbie Lindell

Two residues reprogram immunity receptors for nitrogen-fixing symbiosis pp. 443-450

Magdalini Tsitsikli, Bine Simonsen, Thi-Bich Luu, Maria M. Larsen, Camilla G. Andersen, Kira Gysel, Damiano Lironi, Christina Krönauer, Henriette Rübsam, Simon B. Hansen, René Bærentsen, Jesper Lundsgaard Wulff, Sarah Holt Johansen, Gülendam Sezer, Jens Stougaard, Kasper Røjkjær Andersen and Simona Radutoiu

Mapping Plasmodium transitions and interactions in the Anopheles female pp. 451-458

Yan Yan, Lisa H. Verzier, Elaine Cheung, Federico Appetecchia, Sandra March, Ailsa R. Craven, Esrah Du, Alexandra S. Probst, Tasneem A. Rinvee, Laura E. de Vries, Jamie Kauffman, Sangeeta N. Bhatia, Elisabeth Nelson, Naresh Singh, Duo Peng, W. Robert Shaw and Flaminia Catteruccia

A skin-permeable polymer for non-invasive transdermal insulin delivery pp. 459-467

Qiuyu Wei, Zhi He, Zifan Li, Zhuxian Zhou, Ying Piao, Jianxiang Huang, Yu Geng, Runnan Zhang, Yaqi Fu, Jiayi Ye, Yue Yuan, Haoru Zhu, Jiaheng Zeng, Yan Zhang, Quan Zhou, Mingyu Xu, Shiqun Shao, Jianbin Tang, Jiajia Xiang, Rongjun Chen, Ruhong Zhou and Youqing Shen

Bottom-up design of Ca2+ channels from defined selectivity filter geometry pp. 468-476

Yulai Liu, Connor Weidle, Ljubica Mihaljević, Joseph L. Watson, Zhe Li, Le Tracy Yu, Sagardip Majumder, Andrew J. Borst, Kenneth D. Carr, Ryan D. Kibler, Tamer M. Gamal El-Din, William A. Catterall and David Baker

In situ structural mechanism of epothilone-B-induced CNS axon regeneration pp. 477-487

Satish Bodakuntla, Kenichiro Taira, Yurika Yamada, Pelayo Alvarez-Brecht, A. King Cada, Nirakar Basnet, Rui Zhang, Antonio Martinez-Sanchez, Christian Biertümpfel and Naoko Mizuno

Five important financial moves for PhD students pp. 489-490

Maddi Langweil

Home-field advantage: how local research leads to new discoveries pp. 492-492

Nikki Forrester

2025, volume 648, articles 8092

Growing cities face mounting challenges pp. S1-S1

Richard Hodson

Author Correction: Mechanisms of stretch-mediated skin expansion at single-cell resolution pp. E1-E1

Mariaceleste Aragona, Alejandro Sifrim, Milan Malfait, Yura Song, Jens Van Herck, Sophie Dekoninck, Souhir Gargouri, Gaëlle Lapouge, Benjamin Swedlund, Christine Dubois, Pieter Baatsen, Katlijn Vints, Seungmin Han, Fadel Tissir, Thierry Voet, Benjamin D. Simons and Cédric Blanpain

Author Correction: Brahma safeguards canalization of cardiac mesoderm differentiation pp. E2-E2

Swetansu K. Hota, Kavitha S. Rao, Andrew P. Blair, Ali Khalilimeybodi, Kevin M. Hu, Reuben Thomas, Kevin So, Vasumathi Kameswaran, Jiewei Xu, Benjamin J. Polacco, Ravi V. Desai, Nilanjana Chatterjee, Austin Hsu, Jonathon M. Muncie, Aaron M. Blotnick, Sarah A. B. Winchester, Leor S. Weinberger, Ruth Hüttenhain, Irfan S. Kathiriya, Nevan J. Krogan, Jeffrey J. Saucerman and Benoit G. Bruneau

How cities can keep their cool pp. S2-S4

Michael Eisenstein

Author Correction: A metallic p-wave magnet with commensurate spin helix pp. E3-E3

Rinsuke Yamada, Max T. Birch, Priya R. Baral, Shun Okumura, Ryota Nakano, Shang Gao, Motohiko Ezawa, Takuya Nomoto, Jan Masell, Yuki Ishihara, Kamil K. Kolincio, Ilya Belopolski, Hajime Sagayama, Hironori Nakao, Kazuki Ohishi, Takashi Ohhara, Ryoji Kiyanagi, Taro Nakajima, Yoshinori Tokura, Taka-hisa Arima, Yukitoshi Motome, Moritz M. Hirschmann and Max Hirschberger

Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases pp. E4-E4

Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Kaixin Liang, Ling Xie, Xianming Tan, Sara A. Gibson, Elena Rampanelli, Yan Wang, Stephanie A. Montgomery, W. June Brickey, Meng Deng, Leslie Freeman, Song Zhang, Maureen A. Su, Xian Chen, Yisong Y. Wan and Jenny P.-Y. Ting

Cities are embracing nature for flood defence pp. S5-S7

Erica Gies

Great science happens in great teams — research assessments must try to capture that pp. 8-8

David Budtz Pedersen

Wooden skyscrapers point the way to more sustainable cities pp. S8-S10

Sedeer el-Showk

AI reviewers are here — we are not ready pp. 9-9

Giorgio F. Gilestro

Building mentally healthy cities with neuroscience pp. S11-S11

Simon Makin

What happened at COP30? 4 science take-homes from the climate summit pp. 11-13

Meghie Rodrigues and Jeff Tollefson

Cities aren’t built for women — it’s time to change that pp. S12-S12

Leslie Kern

Data drive city transportation forwards pp. S13-S15

Neil Savage

Cyberattacks’ harm to universities is growing — and so are their effects on research pp. 13-13

Diana Kwon

A brain implant that could rival Neuralink’s enters clinical trials pp. 14-15

Liam Drew

‘Anti-woke’ policies blamed for falling attendance at some US conferences pp. 15-16

Alexandra Witze

‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission pp. 16-17

Rachel Fieldhouse

Geothermal networks let cities warm and cool as one pp. S16-S18

Peter Fairley

Synthetic tongue rates chillies’ heat — and spares human tasters pp. 17-17

Jenna Ahart

We are all mosaics: vast genetic diversity found between cells in a single person pp. 18-18

Heidi Ledford

Will blockbuster obesity drugs revolutionize addiction treatment? pp. 20-22

Elie Dolgin

The ‘silent’ brain cells that shape our behaviour, memory and health pp. 23-25

Alison Abbott

Nature at its weirdest: what metamorphosis reveals about science and ourselves pp. 26-27

Itai Yanai

Spineless creatures, possibly the world’s oldest beer receipt and more: 2025’s best Books in brief pp. 28-30

Andrew Robinson

David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS pp. 31-31

Stephen Goff

A ten-year drive to credit authors for their work — and why there’s still more to do pp. 33-34

Liz Allen, Veronique Kiermer, Simon Porter and Ruth Whittam

Why universities need to radically rethink exams in the age of AI pp. 35-37

Vitomir Kovanović, Abhinava Barthakur, Srećko Joksimović and George Siemens

Alternatives to animal research are not inherently more ethical pp. 38-38

Michele A. Basso

Ease the EU postdoc job market with better routes to innovation pp. 38-38

Bram Servais

Drinking water is at risk during warfare — better protections are needed pp. 38-38

Rongsheng Ning, Yingying Xiang, Mauricius Marques dos Santos and Shane A. Snyder

Memes reveal threats to graduate-student mental health pp. 38-38

Samuel Paulo Cibulski

Fall-prevention clinical trial in rural China shows promising results pp. 39-40

Cynthia Swarnalatha and Sallie E. Lamb

Still no sign of hypothetical sterile-neutrino particle pp. 40-42

Patrick Huber

Even in space, telescopes can’t escape photobombers pp. 42-43

Meredith Rawls

Stop the nonsense: genome editing creates potentially therapeutic transfer RNAs pp. 43-45

Kim M. Keeling

Ethically sourced image data set encourages fairness in AI research pp. 45-46

Walter J. Scheirer

Pancreatic cancer relies on opposing signalling pathways to drive its cellular diversity pp. 46-48

Marc P. Stemmler

Quarks in ‘exotic’ quartets prefer to stick together pp. 48-49

Elena Santopinto

Taiwan invests in genetic resource for health pp. 49-50

Genevieve L. Wojcik

Satellite megaconstellations will threaten space-based astronomy pp. 51-57

Alejandro S. Borlaff, Pamela M. Marcum and Steve B. Howell

Glasses-free 3D display with ultrawide viewing range using deep learning pp. 76-83

Weijie Ma, Zhangrui Zhao, Canyu Zhao, Wanli Ouyang and Han-Sen Zhong

Tin-based perovskite solar cells with a homogeneous buried interface pp. 84-90

Tianpeng Li, Xin Luo, Peilin Wang, Zhi Li, Yimeng Li, Jinhai Huang, Zuoming Jin, Yingguo Yang, Bin Li, Wenqi Zhang, Siyuan Lin, Yichuan Rui, Hua Wang, Qinghong Zhang, Yiqiang Zhan, Bo Xu, Jia Liang and Yabing Qi

A matrix-confined molecular layer for perovskite photovoltaic modules pp. 91-96

Yugang Liang, Guodong Chen, Yao Wang, Yu Zou, Menglei Feng, Yanming Wang, Bowei Li, Yuljae Cho, Yide Chang, Tianle Liu, Taiyang Zhang, Yongbing Lou, Ranran Xu, Lei Lu, Ni Zhang, Ke Meng, Chen Zhu, Chuying Ouyang, Yanfeng Miao, Yongsheng Guo, Yuetian Chen and Yixin Zhao

Fair human-centric image dataset for ethical AI benchmarking pp. 97-108

Alice Xiang, Jerone T. A. Andrews, Rebecca L. Bourke, William Thong, Julienne M. LaChance, Tiffany Georgievski, Apostolos Modas, Aida Rahmattalabbi, Yunhao Ba, Shruti Nagpal, Orestis Papakyriakopoulos, Dora Zhao, Jinru Xue, Victoria Matthews, Linxia Gong, Austin T. Hoag, Mircea Cimpoi, Swami Sankaranarayanan, Wiebke Hutiri, Morgan K. Scheuerman, Albert S. Abedi, Peter Stone, Peter R. Wurman, Hiroaki Kitano and Michael Spranger

Co-option of an ancestral cloacal regulatory landscape during digit evolution pp. 109-116

Aurélie Hintermann, Christopher C. Bolt, M. Brent Hawkins, Guillaume Valentin, Lucille Lopez-Delisle, Madeline M. Ryan, Sandra Gitto, Paula Barrera Gómez, Bénédicte Mascrez, Thomas A. Mansour, Tetsuya Nakamura, Matthew P. Harris, Neil H. Shubin and Denis Duboule

The Taiwan Precision Medicine Initiative provides a cohort for large-scale studies pp. 117-127

Hsin-Chou Yang, Pui-Yan Kwok, Ling-Hui Li, Yi-Min Liu, Yuh-Jyh Jong, Kang-Yun Lee, Da-Wei Wang, Ming-Fang Tsai, Jenn-Hwai Yang, Chien-Hsiun Chen, Erh-Chan Yeh, Chun-yu Wei, Cathy S.-J. Fann, Yen-Tsung Huang, Chia-Wei Chen, Yi-Ju Lee, Shih-Kai Chu, Chih-hsing Ho, Cheng-Shin Yang, Yungling Leo Lee, Hung-Hsin Chen, Ming-Chih Hou, Jeng-Fong Chiou, Shun-Fa Yang, Chih-Hung Wang, Chih-Yang Huang, Kuan-Ming Chiu, Ming Chen, Fu-Tien Chiang, Sing-Lian Lee, Shiou-Sheng Chen, Wei-Jen Yao, Chih-Cheng Chien, Shih-Yao Lin, Fu-Pang Chang, Hsiang-Ling Ho, Yi-Chen Yeh, Wei-Cheng Tseng, Ming-Hwai Lin, Hsiao-Ting Chang, Ling-Ming Tseng, Wen-Yih Liang, Paul Chih-Hsueh Chen, Jen-Fan Hang, Shih-Chieh Lin, Yu-Jiun Chan, Ying-Ju Kuo, Lei-Chi Wang, Chin-Chen Pan, Yu-Cheng Hsieh, Yi-Ming Chen, Tzu-Hung Hsiao, Ching-Heng Lin, Yen-Ju Chen, I-Chieh Chen, Chien-Lin Mao, Shu-Jung Chang, Yen-Lin Chang, Yi-Ju Liao, Chih-Hung Lai, Wei-Ju Lee, Hsin Tung, Ting-Ting Yen, Hsin-Chien Yen, Chun-Ming Shih, Teh-Ying Chou, Tsan-Hon Liou, Chen-Yuan Chiang, Yih-Giun Cherng, Chih-Hwa Chen, Chao-Hua Chiu, Sung-Hui Tseng, Emily Pei-Ying Lin, Ying-Ju Chen, Hui-Ping Chuang, Tsai-Chuan Chen, Wei-Ting Huang, Joey Sin, I-Ling Liu, Yi-Chen Chen, Kuo-Kuang Chao, Yu-Min Wu, Pin-Pin Yu, Lung-Pao Chang, Kuei-Yao Yen, Li-Ching Chang, Yi-Jing Sheen, Yuan-Tsong Chen, Kamhon Kan, Hsiang-Lin Tsai, Yao-Kuang Wang, Ming-Feng Hou, Yuan-Han Yang, Chao-Hung Kuo, Wen-Jeng Wu, Jee-Fu Huang, Inn-Wen Chong, Jong-Rung Tsai, Cheng-Yu Lin, Ming-Chin Yu, Tsong-Hai Lee, Meng-Han Tsai, Yu-Che Ou, Pin-Yuan Chen, Tsung-Hui Hu, Yu-Chiau Shyu, Chih-Kuang Cheng, Yu-Jen Fang, Song-Chou Hsieh, Chien-Hung Chen, Chieh-Chang Chen, Ko-Jen Li, Chin-Hsien Lin, Hsien-Yi Chiu, Chen-Chi Wu, Chun-Yen Chen, Shi-Jye Chu, Feng-Cheng Liu, Fu-Chi Yang, Hsin-An Chang, Wei-liang Chen, Sung-Sen Yang, Yueh-feng Sung, Tso-Fu Wang, Shinn-Zong Lin, Yen-Wen Wu, Chien-Sheng Wu, Ju-Ying Jiang, Gwo-Chin Ma, Ting-Yu Chang, Juey-Jen Hwang, Kuo-Jang Kao, Chen-Fang Hung, Ting-Fang Chiu, Po-Yueh Chen, Kochung Tsui, Ming-Shiang Wu, See-Tong Pang, Shih-Ann Chen, Wei-Ming Chen, Chun-houh Chen, Wayne Huey-Herng Sheu and Jer-Yuarn Wu

Population-specific polygenic risk scores for people of Han Chinese ancestry pp. 128-137

Hung-Hsin Chen, Chien-Hsiun Chen, Ming-Chih Hou, Yun-Ching Fu, Ling-Hui Li, Che-Yu Chou, Erh-Chan Yeh, Ming-Fang Tsai, Chun-houh Chen, Hsin-Chou Yang, Yen-Tsung Huang, Yi-Min Liu, Chun-yu Wei, Jen-Ping Su, Wan-Jia Lin, Elin H. F. Wang, Chi-Lu Chiang, Jeng-Kai Jiang, I-Hui Lee, Kung-Hao Liang, Wei-Sheng Chen, Hung-Cheng Tsai, Shih-Yao Lin, Fu-Pang Chang, Hsiang-Ling Ho, Yi-Chen Yeh, Wei-Cheng Tseng, Ming-Hwai Lin, Hsiao-Ting Chang, Ling-Ming Tseng, Wen-Yih Liang, Paul Chih-Hsueh Chen, Yu-Cheng Hsieh, Yi-Ming Chen, Tzu-Hung Hsiao, Ching-Heng Lin, Yen-Ju Chen, I-Chieh Chen, Chien-Lin Mao, Shu-Jung Chang, Yen-Lin Chang, Yi-Ju Liao, Chih-Hung Lai, Wei-Ju Lee, Hsin Tung, Ting-Ting Yen, Hsin-Chien Yen, Ming-Yao Chen, Ying-Chin Lin, Yung-Ta Kao, Bi-Zhen Kao, Jing-Er Lee, Chi-Li Chung, Ju-Chi Liu, Paul Chan, Chang-Hsien Lin, Chia-Hsin Chen, I-Chen Wu, Lung-Chang Lin, Jiunn-Wei Wang, Shen-liang Shih, Sun-Wung Hsieh, Chih-Hsing Hung, Wei-Ming Li, Chih-Jen Yang, Cheng-Shin Yang, Ru-Hui Weng, Yu-Chi Chen, Chun-Ping Chang, Tai-Hsun Wu, Yu-Chang Lin, Yi-Jing Sheen, Shi-Heng Wang, Sye-Pu Chen, Timothy Raben, Erik Widen, Stephen Hsu, Feng-Jen Hsieh, Dong-Ru Ho, Yu-Huei Huang, Chung-Han Yang, Yu-Shu Huang, Yen-Fu Chen, Hsien-Ming Wu, Ping-Han Tsai, Kuan-Gen Huang, Chih-Yen Chien, Yi-Lwun Ho, Ming-Shiang Wu, Jia-Horng Kao, Yen-Bin Liu, Jyh-Ming Jimmy Juang, Mao-Hsin Lin, Yen-Hung Lin, Ji-Yuh Lee, Hsueh-Ju Lu, Chieh-Hua Lu, An-Chieh Feng, Jhih-Syuan Liu, Chien-Ping Chiang, Nain-Feng Chu, Jung-Chun Lin, Yi-Wei Yeh, En Meng, Chih-Yang Huang, Chi-Cheng Li, Tso-Fu Wang, Kuei-Ying Su, Jia-Kang Wang, Mei-Hsiu Chen, Hua-Fen Chen, Gwo-Chin Ma, Ting-Yu Chang, Fu-Tien Chiang, Hsing-Jung Chang, Kuo-Jang Kao, Chen-Fang Hung, Ching-Yao Tsai, Po-Yueh Chen, Kochung Tsui, Yuan-Tsong Chen, Pui-Yan Kwok, Wayne Huey-Herng Sheu, Shun-Fa Yang, Jyh-Ming Liou, Jaw-Yuan Wang, Jeng-Fong Chiou, Jer-Yuarn Wu and Cathy S. J. Fann

Integration of hunger and hormonal state gates infant-directed aggression pp. 138-145

Mingran Cao, Rachida Ammari, Maxwell X. Chen, Patty Wai, Bradley B. Jamieson, Swang Liang, Basma F. A. Husain, Aashna Sahni, Nathalie Legrave, Irene Salgarella, James MacRae, Molly Strom and Johannes Kohl

The astrocytic ensemble acts as a multiday trace to stabilize memory pp. 146-156

Ken-ichi Dewa, Kodai Kaseda, Aoi Kuwahara, Hideaki Kubotera, Ayato Yamasaki, Natsumi Awata, Atsuko Komori, Mika A. Holtz, Atsushi Kasai, Henrik Skibbe, Norio Takata, Tatsushi Yokoyama, Makoto Tsuda, Genri Numata, Shun Nakamura, Eiki Takimoto, Masayuki Sakamoto, Minako Ito, Takahiro Masuda and Jun Nagai

Lymphoid gene expression supports neuroprotective microglia function pp. 157-165

Pinar Ayata, Jessica M. Crowley, Matthew F. Challman, Vinaya Sahasrabuddhe, Maud Gratuze, Sebastian Werneburg, Diogo Ribeiro, Emma C. Hays, Violeta Durán-Laforet, Travis E. Faust, Philip Hwang, Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Robert E. Murphy, Taoyu Mei, Anna A. Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Claudia De Sanctis, Angie V. Ramirez Jimenez, Megan Crow, Felix D. Weiss, Jason D. Ulrich, Edoardo Marcora, John W. Murray, Felix Meissner, Andreas Beyer, Dan Hasson, John F. Crary, Dorothy P. Schafer, David M. Holtzman, Alison M. Goate, Alexander Tarakhovsky and Anne Schaefer

Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion pp. 166-172

Giovanni Luchetti, Marin V. Miner, Rachael M. Peterson, William P. Scott, Praveen Krishnamoorthy, Eric M. Kofoed, Angel G. Jimenez, Hua Zhang, Man Wah Tan, Rohit Reja, Tommy K. Cheung, Elizabeth Skippington, Yuxin Liang, Christopher M. Rose, Nobuhiko Kayagaki, Kim Newton, Isabella Rauch and Vishva M. Dixit

Niche-specific dermal macrophage loss promotes skin capillary ageing pp. 173-181

Kailin R. Mesa, Kevin A. O’Connor, Charles Ng, Steven P. Salvatore, Alexandra Dolynuk, Michelle Rivera Lomeli and Dan R. Littman

Spatial metabolic gradients in the liver and small intestine pp. 182-190

Laith Z. Samarah, Clover Zheng, Xi Xing, Won Dong Lee, Amichay Afriat, Uthsav Chitra, Michael R. MacArthur, Wenyun Lu, Connor S. R. Jankowski, Cong Ma, Craig J. Hunter, Michael Neinast, Daniel R. Weilandt, Benjamin J. Raphael and Joshua D. Rabinowitz

Prime editing-installed suppressor tRNAs for disease-agnostic genome editing pp. 191-202

Sarah E. Pierce, Steven Erwood, Keyede Oye, Meirui An, Nicholas Krasnow, Emily Zhang, Aditya Raguram, Davis Seelig, Mark J. Osborn and David R. Liu

SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer pp. 203-209

Huafu Li, Linxiang Lan, Hengxing Chen, May Zaw Thin, Hari Ps, Jessica K. Nelson, Ian M. Evans, E. Josue Ruiz, Rongjie Cheng, Li Tran, Mark Allen, Jian Ma, Tingzhuang Yi, Chunming Wang, Yulong He, Naomi Guppy, Anguraj Sadanandam, Shao-Zhen Lin, Changhua Zhang and Axel Behrens

KCTD10 is a sensor for co-directional transcription–replication conflicts pp. 210-219

Jake A. Kloeber, Bin Chen, Guangchao Sun, Charles S. King, Zhiquan Wang, Li Wang, Zheming Wu, Shouhai Zhu, Fei Zhao, Hongran Qin, Yaobin Ouyang, Huaping Xiao, Xinyi Tu, Jing Lu, Yanxia Jiang, Kuntian Luo, Ping Yin, Xinyan Wu, Robert W. Mutter, Jinzhou Huang and Zhenkun Lou

Mechanism of conductance control and neurosteroid binding in NMDA receptors pp. 220-228

Hyunook Kang, Ruben Steigerwald, Elijah Z. Ullman, Max Epstein, Srinu Paladugu, Dennis C. Liotta, Stephen F. Traynelis and Hiro Furukawa

Designing allosteric modulators to change GPCR G protein subtype selectivity pp. 229-238

Madelyn N. Moore, Kelsey L. Person, Valeria L. Robleto, Abigail R. Alwin, Campbell L. Krusemark, Noah Foster, Caroline Ray, Asuka Inoue, Michael R. Jackson, Michael J. Sheedlo, Lawrence S. Barak, Ezequiel Marron Fernandez de Velasco, Steven H. Olson and Lauren M. Slosky

Lessons from a long road to a first-author paper pp. 239-240

Poojashree Chettiar

Introducing the j-metric: a true measure of what matters in academia pp. 240-241

Dariusz Jemielniak

Climbing through the silver mine: my work as a geologist pp. 244-244

Dave Tacon