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2025, volume 641, articles 8065

US brain drain: Nature’s guide to the initiatives drawing scientists abroad pp. 1077-1079

Nisha Gaind, Rachel Fieldhouse, Miryam Naddaf and Giorgia Guglielmi

I told AI to make me a protein. Here’s what it came up with pp. 1079-1080

Ewen Callaway

AI linked to explosion of low-quality biomedical research papers pp. 1080-1081

Miryam Naddaf

Single particle acts as a quantum computer to simulate molecules pp. 1081-1082

Davide Castelvecchi

Science’s ‘Gollum effect’: PhDs bear brunt of territorial behaviour pp. 1082-1083

Julian Nowogrodzki

World first: ultra-powerful CRISPR treatment trialled in a person pp. 1083-1083

Heidi Ledford

NSF plan to slash ‘indirect’ science funding: will it stick? pp. 1084-1084

Dan Garisto

‘Powerful and horrifying’ — David Attenborough’s latest film is a cry to protect our oceans pp. 1095-1096

Chris Simms

Richard Garwin obituary: designer of the hydrogen bomb who advocated for arms control pp. 1097-1097

Ann Finkbeiner

Why space exploration must not be left to a few powerful nations pp. 1098-1100

Timiebi Aganaba, Adam Fish, Duane Hamacher, Alvin Harvey, Daniel Joinbee, Anthony Milligan, Chakad Ojani, Niiyokamigaabaw Deondre Smiles, Peter Swanton, Hilding Neilson and Brad Tucker

Track record: unexpectedly early reptile claw prints found pp. 1103-1104

Stuart S. Sumida

Black hole flings out clumps of gas pp. 1104-1105

Manuela Bischetti

Psychedelics reduce fear by targeting immune cells that modulate brain cells pp. 1105-1108

Yun Chen and Marco Colonna

How and when North America’s deepest river gorge formed pp. 1107-1107

Andrew Mitchinson

The cell-division cycle is faster in cell types prone to forming cancer pp. 1108-1109

Helen K. Matthews

Scientists with ADHD speak up: when fire meets focus pp. 1339-1341

Julian Nowogrodzki

How artificial intelligence is transforming pathology pp. 1342-1344

Diana Kwon

I apply my aquatic-science training to empower Tanzania’s seaweed farmers pp. 1346-1346

James Mitchell Crow

2025, volume 641, articles 8064

Philanthropic funders: team up to jump-start innovative science pp. 823-823

Cynthia Friend

When the government cancels your research grant, here’s what you can do pp. 824-824

Lisa Fazio

DeepMind unveils ‘spectacular’ general-purpose science AI pp. 827-828

Elizabeth Gibney

US brain drain: the scientists seeking jobs abroad amid Trump’s assault on research pp. 828-829

Giorgia Guglielmi, Miryam Naddaf and Rachel Fieldhouse

‘AI models are capable of novel research’: OpenAI’s chief scientist on what to expect pp. 830-830

Elizabeth Gibney

US environmental agency halts funding for its main science division pp. 831-832

Jeff Tollefson

Fossil claw marks show reptiles arose much earlier than thought pp. 832-833

Rita Aksenfeld

Renewal of NIH grants linked to more innovative results, study finds pp. 833-834

Humberto Basilio

Migraine drug is first to tackle debilitating early symptoms pp. 834-834

Fred Schwaller

Are groundbreaking science discoveries becoming harder to find? pp. 836-839

David Matthews

Who were the ancient Denisovans? Fossils reveal secrets about the mysterious humans pp. 840-842

Michael Marshall

How ‘organized looting and plunder’ drove Britain’s second scientific revolution pp. 843-844

Zaheer Baber

Mighty microbes — the invisible forces that can save the world pp. 845-846

Raquel S. Peixoto

Hurricane risk in a changing climate — the role of uncertainty pp. 848-851

Adam H. Sobel and Kerry A. Emanuel

Data resources must be protected from political interference pp. 852-852

Kaili Zhang

AI bots threaten online scientific infrastructure pp. 852-852

Michael C. Orr, John S. Ascher and John Pickering

AI-generated literature reviews threaten scientific progress pp. 852-852

Xusen Cheng and Lulu Zhang

Don’t forget the lessons of the McCarthy era pp. 852-852

Jeremy W. Jacobs and Garrett S. Booth

Clinical trials test the safety of stem-cell therapy for Parkinson’s disease pp. 853-854

Hideyuki Okano

Early barred galaxy raises questions about cosmic evolution pp. 854-855

Deanne Fisher

Memories of a cold place trigger bodily responses to warm up pp. 856-858

Pamela Toh and Abha Karki Rajbhandari

Mother–infant bonds in wild chimpanzees resemble those of humans pp. 856-856

Andrew Mitchinson

Dying stars give a second wind to exoplanet formation pp. 858-859

Kendall Sullivan

Heart-attack outcomes are worse in the morning when activity of protein duo dips pp. 859-860

Ariana Kupai and Clara Peek

Large gas inflow driven by a matured galactic bar in the early Universe pp. 861-865

Shuo Huang, Ryohei Kawabe, Hideki Umehata, Kotaro Kohno, Yoichi Tamura and Toshiki Saito

A retrograde planet in a tight binary star system with a white dwarf pp. 866-870

Ho Wan Cheng, Trifon Trifonov, Man Hoi Lee, Faustine Cantalloube, Sabine Reffert, David Ramm and Andreas Quirrenbach

Proton transport from the antimatter factory of CERN pp. 871-875

M. Leonhardt, D. Schweitzer, F. Abbass, K. K. Anjum, B. Arndt, S. Erlewein, S. Endoh, P. Geissler, T. Imamura, J. I. Jäger, B. M. Latacz, P. Micke, F. Voelksen, H. Yildiz, K. Blaum, J. A. Devlin, Y. Matsuda, C. Ospelkaus, W. Quint, A. Soter, J. Walz, Y. Yamazaki, S. Ulmer and C. Smorra

Tunable vacuum-field control of fractional and integer quantum Hall phases pp. 884-889

Josefine Enkner, Lorenzo Graziotto, Dalin Boriçi, Felice Appugliese, Christian Reichl, Giacomo Scalari, Nicolas Regnault, Werner Wegscheider, Cristiano Ciuti and Jérôme Faist

Observation of edge and bulk states in a three-site Kitaev chain pp. 890-895

Sebastiaan L. D. Haaf, Yining Zhang, Qingzhen Wang, Alberto Bordin, Chun-Xiao Liu, Ivan Kulesh, Vincent P. M. Sietses, Christian G. Prosko, Di Xiao, Candice Thomas, Michael J. Manfra, Michael Wimmer and Srijit Goswami

Unconventional domain tessellations in moiré-of-moiré lattices pp. 896-903

Daesung Park, Changwon Park, Kunihiro Yananose, Eunjung Ko, Byunghyun Kim, Rebecca Engelke, Xi Zhang, Konstantin Davydov, Matthew Green, Hyun-Mi Kim, Sang Hwa Park, Jae Heon Lee, Seul-Gi Kim, Hyeongkeun Kim, Kenji Watanabe, Takashi Taniguchi, Sang Mo Yang, Ke Wang, Philip Kim, Young-Woo Son and Hyobin Yoo

Ultrahigh-pressure crystallographic passage towards metallic hydrogen pp. 904-909

Cheng Ji, Bing Li, Jie Luo, Yongsheng Zhao, Yuan Liu, Konstantin Glazyrin, Alexander Björling, Lucas A. B. Marçal, Maik Kahnt, Sebastian Kalbfleisch, Wenjun Liu, Yang Gao, Junyue Wang, Wendy L. Mao, Hanyu Liu, Yanming Ma, Yang Ding, Wenge Yang and Ho-Kwang Mao

Exploring pathways for world development within planetary boundaries pp. 910-916

Detlef P. van Vuuren, Jonathan C. Doelman, Isabela Schmidt Tagomori, Arthur H. W. Beusen, Sarah E. Cornell, Johan Röckstrom, Aafke M. Schipper, Elke Stehfest, Geanderson Ambrosio, Maarten Berg, Lex Bouwman, Vassilis Daioglou, Mathijs Harmsen, Paul Lucas, Kaj-Ivar Wijst and Willem-Jan Zeist

Global impoverishment of natural vegetation revealed by dark diversity pp. 917-924

Meelis Pärtel, Riin Tamme, Carlos P. Carmona, Kersti Riibak, Mari Moora, Jonathan A. Bennett, Alessandro Chiarucci, Milan Chytrý, Francesco Bello, Ove Eriksson, Susan Harrison, Robert John Lewis, Angela T. Moles, Maarja Öpik, Jodi N. Price, Vistorina Amputu, Diana Askarizadeh, Zohreh Atashgahi, Isabelle Aubin, Francisco M. Azcárate, Matthew D. Barrett, Maral Bashirzadeh, Zoltán Bátori, Natalie Beenaerts, Kolja Bergholz, Kristine Birkeli, Idoia Biurrun, José M. Blanco-Moreno, Kathryn J. Bloodworth, Laura Boisvert-Marsh, Bazartseren Boldgiv, Pedro H. S. Brancalion, Francis Q. Brearley, Charlotte Brown, C. Guillermo Bueno, Gabriella Buffa, James F. Cahill, Juan A. Campos, Giacomo Cangelmi, Michele Carbognani, Christopher Carcaillet, Bruno E. L. Cerabolini, Richard Chevalier, Jan S. Clavel, José M. Costa, Sara A. O. Cousins, Jan Čuda, Mariana Dairel, Michele Dalle Fratte, Alena Danilova, John Davison, Balázs Deák, Silvia Vecchio, Iwona Dembicz, Jürgen Dengler, Jiri Dolezal, Xavier Domene, Miroslav Dvorsky, Hamid Ejtehadi, Lucas Enrico, Dmitrii Epikhin, Anu Eskelinen, Franz Essl, Gaohua Fan, Edy Fantinato, Fatih Fazlioglu, Eduardo Fernández-Pascual, Arianna Ferrara, Alessandra Fidelis, Markus Fischer, Maren Flagmeier, T’ai G. W. Forte, Lauchlan H. Fraser, Junichi Fujinuma, Fernando F. Furquim, Berle Garris, Heath W. Garris, Melisa A. Giorgis, Gianpietro Giusso del Galdo, Ana González-Robles, Megan K. Good, Moisès Guardiola, Riccardo Guarino, Irene Guerrero, Joannès Guillemot, Behlül Güler, Yinjie Guo, Stef Haesen, Martin Hejda, Ruben H. Heleno, Toke T. Høye, Richard Hrivnák, Yingxin Huang, John T. Hunter, Dmytro Iakushenko, Ricardo Ibáñez, Nele Ingerpuu, Severin D. H. Irl, Eva Janíková, Florian Jansen, Florian Jeltsch, Anke Jentsch, Borja Jiménez-Alfaro, Madli Jõks, Mohammad H. Jouri, Sahar Karami, Negin Katal, András Kelemen, Bulat I. Khairullin, Anzar A. Khuroo, Kimberly J. Komatsu, Marie Konečná, Ene Kook, Lotte Korell, Natalia Koroleva, Kirill A. Korznikov, Maria V. Kozhevnikova, Łukasz Kozub, Lauri Laanisto, Helena Lager, Vojtech Lanta, Romina G. Lasagno, Jonas J. Lembrechts, Liping Li, Aleš Lisner, Houjia Liu, Kun Liu, Xuhe Liu, Manuel Esteban Lucas-Borja, Kristin Ludewig, Katalin Lukács, Jona Luther-Mosebach, Petr Macek, Michela Marignani, Richard Michalet, Tamás Miglécz, Jesper Erenskjold Moeslund, Karlien Moeys, Daniel Montesinos, Eduardo Moreno-Jiménez, Ivan Moysiyenko, Ladislav Mucina, Miriam Muñoz-Rojas, Raytha A. Murillo, Sylvia M. Nambahu, Lena Neuenkamp, Signe Normand, Arkadiusz Nowak, Paloma Nuche, Tatjana Oja, Vladimir G. Onipchenko, Kalina L. Pachedjieva, Bruno Paganeli, Begoña Peco, Ana M. L. Peralta, Aaron Pérez-Haase, Pablo L. Peri, Alessandro Petraglia, Gwendolyn Peyre, Pedro Antonio Plaza-Álvarez, Jan Plue, Honor C. Prentice, Vadim E. Prokhorov, Dajana Radujković, Soroor Rahmanian, Triin Reitalu, Michael Ristow, Agnès A. Robin, Ana Belén Robles, Daniel A. Rodríguez Ginart, Raúl Román, Ruben E. Roos, Leonardo Rosati, Jiří Sádlo, Karina Salimbayeva, Rut Sánchez de Dios, Khaliun Sanchir, Cornelia Sattler, John D. Scasta, Ute Schmiedel, Julian Schrader, Nick L. Schultz, Giacomo Sellan, Josep M. Serra-Diaz, Giulia Silan, Hana Skálová, Nadiia Skobel, Judit Sonkoly, Kateřina Štajerová, Ivana Svitková, Sebastian Świerszcz, Andrew J. Tanentzap, Fallon M. Tanentzap, Rubén Tarifa, Pablo Tejero, Dzhamal K. Tekeev, Michael Tholin, Ruben S. Thormodsæter, Yichen Tian, Alla Tokaryuk, Csaba Tölgyesi, Marcello Tomaselli, Enrico Tordoni, Péter Török, Béla Tóthmérész, Aurèle Toussaint, Blaise Touzard, Diego P. F. Trindade, James L. Tsakalos, Sevda Türkiş, Enrique Valencia, Mercedes Valerio, Orsolya Valkó, Koenraad Meerbeek, Vigdis Vandvik, Jesus Villellas, Risto Virtanen, Michaela Vítková, Martin Vojík, Andreas Hessberg, Jonathan Oppen, Viktoria Wagner, Ji-Zhong Wan, Chun-Jing Wang, Sajad A. Wani, Lina Weiss, Tricia Wevill, Sa Xiao, Oscar Zárate Martínez and Martin Zobel

High continuity of forager ancestry in the Neolithic period of the eastern Maghreb pp. 925-931

Mark Lipson, Harald Ringbauer, Giulio Lucarini, Nabiha Aouadi, Louiza Aoudia, Lotfi Belhouchet, Olivia Cheronet, Ariane-Rym Dahmani, Francesco Genchi, Francesco Pastina, Michaela Lucci, Henry Lumley, Nabila Mansouri, Alessia Nava, Fatma Touj, Swapan Mallick, Nadin Rohland, Alfredo Coppa, Ron Pinhasi and David Reich

Spatially resolved mapping of cells associated with human complex traits pp. 932-941

Liyang Song, Wenhao Chen, Junren Hou, Minmin Guo and Jian Yang

Cold memories control whole-body thermoregulatory responses pp. 942-951

Andrea Muñoz Zamora, Aaron Douglas, Paul B. Conway, Esteban Urrieta, Taylor Moniz, James D. O’Leary, Lydia Marks, Christine A. Denny, Clara Ortega- de San Luis, Lydia Lynch and Tomás J. Ryan

A prospective code for value in the serotonin system pp. 952-959

Emerson F. Harkin, Cooper D. Grossman, Jeremiah Y. Cohen, Jean-Claude Béïque and Richard Naud

Rapid emergence of latent knowledge in the sensory cortex drives learning pp. 960-970

Céline Drieu, Ziyi Zhu, Ziyun Wang, Kylie Fuller, Aaron Wang, Sarah Elnozahy and Kishore Kuchibhotla

Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease pp. 971-977

Nobukatsu Sawamoto, Daisuke Doi, Etsuro Nakanishi, Masanori Sawamura, Takayuki Kikuchi, Hodaka Yamakado, Yosuke Taruno, Atsushi Shima, Yasutaka Fushimi, Tomohisa Okada, Tetsuhiro Kikuchi, Asuka Morizane, Satoe Hiramatsu, Takayuki Anazawa, Takero Shindo, Kentaro Ueno, Satoshi Morita, Yoshiki Arakawa, Yuji Nakamoto, Susumu Miyamoto, Ryosuke Takahashi and Jun Takahashi

Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease pp. 978-983

V. Tabar, H. Sarva, A. M. Lozano, A. Fasano, S. K. Kalia, K. K. H. Yu, C. Brennan, Y. Ma, S. Peng, D. Eidelberg, M. Tomishima, S. Irion, W. Stemple, N. Abid, A. Lampron, L. Studer and C. Henchcliffe

Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines pp. 984-992

Paweł S. Krawczyk, Michał Mazur, Wiktoria Orzeł, Olga Gewartowska, Sebastian Jeleń, Wiktor Antczak, Karolina Kasztelan, Aleksandra Brouze, Katarzyna Matylla-Kulińska, Natalia Gumińska, Bartosz Tarkowski, Ewelina P. Owczarek, Kamila Affek, Paweł Turowski, Agnieszka Tudek, Małgorzata Sroka, Tomasz Śpiewla, Monika Kusio-Kobiałka, Aleksandra Wesołowska, Dominika Nowis, Jakub Golab, Joanna Kowalska, Jacek Jemielity, Andrzej Dziembowski and Seweryn Mroczek

Histological signatures map anti-fibrotic factors in mouse and human lungs pp. 993-1004

Jason L. Guo, Michelle Griffin, Jung-Ki Yoon, David M. Lopez, Yili Zhu, John M. Lu, Georgios Mikos, Jennifer B. L. Parker, Shamik Mascharak, Camille Brenac, Nicholas J. Guardino, Darren B. Abbas, Dayan J. Li, Caleb Valencia, Norah E. Liang, Michael Januszyk, Howard Y. Chang, Derrick C. Wan, Tushar J. Desai and Michael T. Longaker

Macrophages harness hepatocyte glutamate to boost liver regeneration pp. 1005-1016

María del Mar Rigual, Mariana Angulo-Aguado, Sladjana Zagorac, Ruth Álvarez-Díaz, Marta Benítez-Mondéjar, Fengming Yi, Carlos Martínez-Garay, Karla Santos- de-Frutos, Eunjeong Kim, Ramón Campos-Olivas and Nabil Djouder

BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury pp. 1017-1028

Wei Ruan, Tao Li, In Hyuk Bang, Jaewoong Lee, Wankun Deng, Xinxin Ma, Cong Luo, Fang Du, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Katherine Figarella, Yu A. An, Yin-Ying Wang, Yafen Liang, Matthew DeBerge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua M. Gorham, Jonathan G. Seidman, Christine E. Seidman, Sary F. Aranki, Ragini Nair, Lei Li, Jagat Narula, Zhongming Zhao, Alemayehu A. Gorfe, Jochen D. Muehlschlegel, Kuang-Lei Tsai and Holger K. Eltzschig

Gene-modified pig-to-human liver xenotransplantation pp. 1029-1036

Kai-Shan Tao, Zhao-Xu Yang, Xuan Zhang, Hong-Tao Zhang, Shu-Qiang Yue, Yan-Ling Yang, Wen-Jie Song, Wang De-Sheng, Zheng-Cai Liu, Hai-Min Li, Yong Chen, Rui Ding, Shi-Ren Sun, Ming Yu, Ji-Peng Li, Wei-Xun Duan, Zhe Wang, Jing-Wen Wang, Jia-Yun Liu, Min-Wen Zheng, Xi-Jing Zhang, Wen Yin, Wei-Jun Qin, Dong-Mei Bian, Lin Li, Min Li, Zhi-Bin Lin, Hao Xu, Dan Wei, Hong Zhang, Juan-Li Duan, Deng-Ke Pan, Hai-Long Dong, Lin Wang and Ke-Feng Dou

Spatial multi-omics reveals cell-type-specific nuclear compartments pp. 1037-1047

Yodai Takei, Yujing Yang, Jonathan White, Isabel N. Goronzy, Jina Yun, Meera Prasad, Lincoln J. Ombelets, Simone Schindler, Prashant Bhat, Mitchell Guttman and Long Cai

Oxidation of retromer complex controls mitochondrial translation pp. 1048-1058

Junbing Zhang, Md Yousuf Ali, Harrison Byron Chong, Pei-Chieh Tien, James Woods, Carolina Noble, Tristan Vornbäumen, Zehra Ordulu, Anthony P. Possemato, Stefan Harry, Jay Miguel Fonticella, Lina Fellah, Drew Harrison, Maolin Ge, Neha Khandelwal, Yingfei Huang, Maëva Chauvin, Anica Tamara Bischof, Grace Marie Hambelton, Magdy Farag Gohar, Siwen Zhang, MinGyu Choi, Sara Bouberhan, Esther Oliva, Mari Mino-Kenudson, Natalya N. Pavlova, Michael Lawrence, Justin F. Gainor, Sean A. Beausoleil, Nabeel Bardeesy, Raul Mostoslavsky, David Pépin, Christopher J. Ott, Brian Liau and Liron Bar-Peled

#OpenToWork: how laid-off US scientists are coping with shattered careers pp. 1059-1061

Virginia Gewin

People and dogs team up to protect sea turtles in Cabo Verde pp. 1064-1064

Patricia Maia Noronha

2025, volume 641, articles 8063

Publisher Correction: irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA pp. E8-E8

Luca Ducoli, Brian J. Zarnegar, Douglas F. Porter, Robin M. Meyers, Weili Miao, Nicholas M. Riley, Suhas Srinivasan, Leandra V. Jackrazi, Yen-Yu Yang, Zhouxian Li, Yinsheng Wang, Carolyn R. Bertozzi, Ryan A. Flynn and Paul A. Khavari

My PhD adviser was fired and I was collateral damage. I learnt how to build resilience into graduate school pp. 561-561

Donovan Dennis

Trump proposes unprecedented budget cuts to US science pp. 565-566

Jeff Tollefson, Dan Garisto, Max Kozlov and Alexandra Witze

Controversial geoengineering projects to test Earth-cooling tech funded by UK agency pp. 567-568

Jonathan O’Callaghan

AI scientist ‘team’ joins the search for extraterrestrial life pp. 568-569

Celeste Biever

Blood of man who’s had 200 snake bites helps make a potent antivenom pp. 569-570

Katherine Bourzac

Revealed: the unusual mathematics that gives rose petals their shape pp. 570-571

Davide Castelvecchi

How climate change will burden our children: data reveal a lifetime of extreme heat pp. 571-572

Celeste Biever

‘Second chance’: convicted US chemist Charles Lieber moves to Chinese university pp. 572-572

Rachel Fieldhouse

Is it OK for AI to write science papers? Nature survey shows researchers are split pp. 574-578

Diana Kwon

How political attacks could crush the mRNA vaccine revolution pp. 580-582

Elie Dolgin

Hunting extreme microbes that redefine the limits of life pp. 583-584

Andreas Teske

Why bad philosophy is stopping progress in physics pp. 585-587

Carlo Rovelli

A pope, a polymath and plucky women: Books in brief pp. 587-587

Andrew Robinson

The scars of war last for centuries: how we understand collective trauma needs to change pp. 589-591

Cindy C. Sangalang

US researchers must stand up to protect freedoms, not just funding pp. 592-593

Andrew M. Leifer, Andrea J. Liu and Sidney R. Nagel

China needs to deal with discarded electric-vehicle batteries pp. 594-594

Avik Sinha, Jing Wu, Muhammad Sheraz and Quande Qin

Empower communities to fight climate change at grassroots level pp. 594-594

Yifan Zhong

‘Loss and damage fund’ for climate change needs broader remit pp. 594-594

Casey M. Ryan and A. Carla Staver

Do universities serve their community? pp. 594-594

Brian T. Murphy

Earth’s climatic past illuminates future South Asian monsoon patterns pp. 595-596

Francesco S. R. Pausata and Thejna Tharammal

Sunflower ‘virgin births’ enable accelerated crop breeding pp. 596-598

Marco Todesco and Loren H. Rieseberg

Black hole fly-by modelled with landmark precision pp. 598-599

Zhengwen Liu

Highly sensitive method captures rare RNAs in blood to search for disease pp. 599-600

Trine B. Rounge and Jonas Paulsen

Airborne microplastics enter plant leaves and end up in our food pp. 601-602

Willie Peijnenburg

North America’s birds are declining where they should be thriving pp. 602-602

Holly Smith

Emergence of Calabi–Yau manifolds in high-precision black-hole scattering pp. 603-607

Mathias Driesse, Gustav Uhre Jakobsen, Albrecht Klemm, Gustav Mogull, Christoph Nega, Jan Plefka, Benjamin Sauer and Johann Usovitsch

Water ice in the debris disk around HD 181327 pp. 608-611

Chen Xie, Christine H. Chen, Carey M. Lisse, Dean C. Hines, Tracy Beck, Sarah K. Betti, Noemí Pinilla-Alonso, Carl Ingebretsen, Kadin Worthen, András Gáspár, Schuyler G. Wolff, Bryce T. Bolin, Laurent Pueyo, Marshall D. Perrin, John A. Stansberry and Jarron M. Leisenring

Quantum error correction of qudits beyond break-even pp. 612-618

Benjamin L. Brock, Shraddha Singh, Alec Eickbusch, Volodymyr V. Sivak, Andy Z. Ding, Luigi Frunzio, Steven M. Girvin and Michel H. Devoret

Superconducting gap of H3S measured by tunnelling spectroscopy pp. 619-624

Feng Du, Alexander P. Drozdov, Vasily S. Minkov, Fedor F. Balakirev, Panpan Kong, G. Alexander Smith, Jiafeng Yan, Bin Shen, Philipp Gegenwart and Mikhail I. Eremets

Twist-programmable superconductivity in spin–orbit-coupled bilayer graphene pp. 625-631

Yiran Zhang, Gal Shavit, Huiyang Ma, Youngjoon Han, Chi Wang Siu, Ankan Mukherjee, Kenji Watanabe, Takashi Taniguchi, David Hsieh, Cyprian Lewandowski, Felix Oppen, Yuval Oreg and Stevan Nadj-Perge

Superconductivity and spin canting in spin–orbit-coupled trilayer graphene pp. 632-638

Caitlin L. Patterson, Owen I. Sheekey, Trevor B. Arp, Ludwig F. W. Holleis, Jin Ming Koh, Youngjoon Choi, Tian Xie, Siyuan Xu, Yi Guo, Hari Stoyanov, Evgeny Redekop, Canxun Zhang, Grigory Babikyan, David Gong, Haoxin Zhou, Xiang Cheng, Takashi Taniguchi, Kenji Watanabe, Martin E. Huber, Chenhao Jin, Étienne Lantagne-Hurtubise, Jason Alicea and Andrea F. Young

Wireless transmission of internal hazard signals in Li-ion batteries pp. 639-645

Jinbao Fan, Chenchen Liu, Na Li, Le Yang, Xiao-Guang Yang, Bowen Dou, Shujuan Hou, Xuning Feng, Hanqing Jiang, Hong Li, Wei-Li Song, Lei Sun, Hao-Sen Chen, Huajian Gao and Daining Fang

Strategic atom replacement enables regiocontrol in pyrazole alkylation pp. 646-652

Alexander Fanourakis, Yahia Ali, Liao Chen, Patrick Q. Kelly, Abigail J. Bracken, Christopher B. Kelly and Mark D. Levin

Past warm intervals inform the future South Asian summer monsoon pp. 653-659

Linqiang He, Tianjun Zhou and Zhun Guo

Trends in the seasonal amplitude of atmospheric methane pp. 660-665

Gang Liu, Lu Shen, Philippe Ciais, Xin Lin, Didier Hauglustaine, Xin Lan, Alexander J. Turner, Yi Xi, Yu Zhu and Shushi Peng

Leaf absorption contributes to accumulation of microplastics in plants pp. 666-673

Ye Li, Junjie Zhang, Li Xu, Ruoqi Li, Rui Zhang, Mengxi Li, Chunmei Ran, Ziyu Rao, Xing Wei, Mingli Chen, Lu Wang, Zhiwanxin Li, Yining Xue, Chu Peng, Chunguang Liu, Hongwen Sun, Baoshan Xing and Lei Wang

A Jurassic acanthocephalan illuminates the origin of thorny-headed worms pp. 674-680

Cihang Luo, Luke A. Parry, Brendon E. Boudinot, Shengyu Wang, Edmund A. Jarzembowski, Haichun Zhang and Bo Wang

Clonal dynamics and somatic evolution of haematopoiesis in mouse pp. 681-689

Chiraag D. Kapadia, Nicholas Williams, Kevin J. Dawson, Caroline Watson, Matthew J. Yousefzadeh, Duy Le, Kudzai Nyamondo, Sreeya Kodavali, Alex Cagan, Sarah Waldvogel, Xiaoyan Zhang, Josephine Fuente, Daniel Leongamornlert, Emily Mitchell, Marcus A. Florez, Krzysztof Sosnowski, Rogelio Aguilar, Alejandra Martell, Anna Guzman, David Harrison, Laura J. Niedernhofer, Katherine Y. King, Peter J. Campbell, Jamie Blundell, Margaret A. Goodell and Jyoti Nangalia

Dual neuromodulatory dynamics underlie birdsong learning pp. 690-698

Jiaxuan Qi, Drew C. Schreiner, Miles Martinez, John Pearson and Richard Mooney

Natural behaviour is learned through dopamine-mediated reinforcement pp. 699-706

Jonathan Kasdin, Alison Duffy, Nathan Nadler, Arnav Raha, Adrienne L. Fairhall, Kimberly L. Stachenfeld and Vikram Gadagkar

Basis functions for complex social decisions in dorsomedial frontal cortex pp. 707-717

Marco K. Wittmann, Yongling Lin, Deng Pan, Moritz N. Braun, Cormac Dickson, Lisa Spiering, Shuyi Luo, Caroline Harbison, Ayat Abdurahman, Sorcha Hamilton, Nadira S. Faber, Nima Khalighinejad, Patricia L. Lockwood and Matthew F. S. Rushworth

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease pp. 718-731

Kimitoshi Kimura, Ayshwarya Subramanian, Zhuoran Yin, Ahad Khalilnezhad, Yufan Wu, Danyang He, Karen O. Dixon, Udbhav Kasyap Chitta, Xiaokai Ding, Niraj Adhikari, Isabell Guzchenko, Xiaoming Zhang, Ruihan Tang, Thomas Pertel, Samuel A. Myers, Aastha Aastha, Masashi Nomura, Ghazaleh Eskandari-Sedighi, Vasundhara Singh, Lei Liu, Conner Lambden, Kilian L. Kleemann, Neha Gupta, Jen-Li Barry, Ana Durao, Yiran Cheng, Sebastian Silveira, Huiyuan Zhang, Aamir Suhail, Toni Delorey, Orit Rozenblatt-Rosen, Gordon J. Freeman, Dennis J. Selkoe, Howard L. Weiner, Mathew Blurton-Jones, Carlos Cruchaga, Aviv Regev, Mario L. Suvà, Oleg Butovsky and Vijay K. Kuchroo

Haploid facultative parthenogenesis in sunflower sexual reproduction pp. 732-739

Jian Lv, Dawei Liang, Eric Bumann, Virginie Mirleau Thebaud, Huaibing Jin, Changbao Li, Clemence Paris, Yinghui Dan, Chao Li, Ruijie Cui, Xianxia Chen, David Szwerdszarf, Peter Wittich, Bobby Clegg, Agustin Tassara, Hongmei Dan, Xiaolong Tian, Zhiqiang Liu, Wen Cai, Bin Sun, Jared Carter, Paul Drayton, Federico Bock and Timothy Kelliher

Matrix-producing neutrophils populate and shield the skin pp. 740-748

Tommaso Vicanolo, Alaz Özcan, Jackson LiangYao Li, Carla Huerta-López, Iván Ballesteros, Andrea Rubio-Ponce, Andra C. Dumitru, Jose Ángel Nicolás-Ávila, Miguel Molina-Moreno, Pablo Reyes-Gutierrez, Andrew D. Johnston, Catherine Martone, Eric Greto, Antonio Quílez-Alvarez, Enrique Calvo, Elena Bonzon-Kulichenko, Rebeca Álvarez-Velez, Ming Yao Chooi, Immanuel Kwok, Blanca González-Bermúdez, Benoit Malleret, Francisco M. Espinosa, Ming Zhang, Yu-Long Wang, Dasheng Sun, Shu Zhen Chong, Ali El-Armouche, Kevin K. Kim, Irina A. Udalova, Valentina Greco, Ricardo Garcia, Jesús Vázquez, Ana Dopazo, Gustavo R. Plaza, Jorge Alegre-Cebollada, Stefan Uderhardt, Lai Guan Ng and Andrés Hidalgo

A human brain map of mitochondrial respiratory capacity and diversity pp. 749-758

Eugene V. Mosharov, Ayelet M. Rosenberg, Anna S. Monzel, Corey A. Osto, Linsey Stiles, Gorazd B. Rosoklija, Andrew J. Dwork, Snehal Bindra, Alex Junker, Ya Zhang, Masashi Fujita, Madeline B. Mariani, Mihran Bakalian, David Sulzer, Philip L. Jager, Vilas Menon, Orian S. Shirihai, J. John Mann, Mark D. Underwood, Maura Boldrini, Michel Thiebaut de Schotten and Martin Picard

An ultrasensitive method for detection of cell-free RNA pp. 759-768

Monica C. Nesselbush, Bogdan A. Luca, Young-Jun Jeon, Isabel Jabara, Catherine B. Meador, Andrea Garofalo, Michael S. Binkley, Angela B. Hui, Iris van ‘t Erve, Nova Xu, William Y. Shi, Kevin J. Liu, Takeshi Sugio, Noah Kastelowitz, Emily G. Hamilton, Chih Long Liu, Mari Olsen, Rene F. Bonilla, Yi Peng Wang, Alice Jiang, Brianna Lau, Jordan Eichholz, Mandeep Banwait, Joseph Schroers-Martin, Jan Boegeholz, Daniel A. King, Helen Luikart, Mohammad S. Esfahani, Mahya Mehrmohamadi, Henning Stehr, Tyler Raclin, Robert Tibshirani, Kiran Khush, Sandy Srinivas, Helena Yu, Angela J. Rogers, Viswam S. Nair, James M. Isbell, Bob T. Li, Zofia Piotrowska, Lecia V. Sequist, Aaron N. Hata, Joel W. Neal, Heather A. Wakelee, Andrew J. Gentles, Ash A. Alizadeh and Maximilian Diehn

irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA pp. 769-778

Luca Ducoli, Brian J. Zarnegar, Douglas F. Porter, Robin M. Meyers, Weili Miao, Nicholas M. Riley, Suhas Srinivasan, Leandra V. Jackrazi, Yen-Yu Yang, Zhouxian Li, Yinsheng Wang, Carolyn R. Bertozzi, Ryan A. Flynn and Paul A. Khavari

Histone H1 deamidation facilitates chromatin relaxation for DNA repair pp. 779-787

Yuan Tian, Tingting Feng, Jun Zhang, Qingren Meng, Wenxin Zhan, Ming Tang, Chaohua Liu, Mengyan Li, Wenhui Tao, Yuxin Shu, Yu Zhang, Feng Chen, Shunichi Takeda, Qian Zhu, Xiaopeng Lu and Wei-Guo Zhu

Glutamate gating of AMPA-subtype iGluRs at physiological temperatures pp. 788-796

Anish Kumar Mondal, Elisa Carrillo, Vasanthi Jayaraman and Edward C. Twomey

Structure and mechanism of the plastid/parasite ATP/ADP translocator pp. 797-804

Huajian Lin, Jian Huang, Tianming Li, Wenjuan Li, Yutong Wu, Tianjiao Yang, Yuwei Nian, Xiang Lin, Jiangqin Wang, Ruiying Wang, Xiaohui Zhao, Nannan Su, Jinru Zhang, Xudong Wu and Minrui Fan

Six striking images showcase scientific fieldwork pp. 805-808

Jack Leeming

Brain tissues, assemble! Inside the push to build better brain models pp. 809-812

Elie Dolgin

What language do bats speak? I’m trying to find out pp. 814-814

Tavares Cebola

2025, volume 641, articles 8062

Author Correction: Continued Atlantic overturning circulation even under climate extremes pp. E2-E2

J. A. Baker, M. J. Bell, L. C. Jackson, G. K. Vallis, A. J. Watson and R. A. Wood

Author Correction: Structure of the human dopamine transporter in complex with cocaine pp. E3-E3

Jeppe C. Nielsen, Kristine Salomon, Iris E. Kalenderoglou, Sarah Bargmeyer, Tillmann Pape, Azadeh Shahsavar and Claus J. Loland

Author Correction: Global influence of soil texture on ecosystem water limitation pp. E4-E4

Fabian J. P. Wankmüller, Louis Delval, Peter Lehmann, Martin J. Baur, Andrea Cecere, Sebastian Wolf, Dani Or, Mathieu Javaux and Andrea Carminati

Publisher Correction: Oncolytic virus VG161 in refractory hepatocellular carcinoma pp. E5-E5

Yinan Shen, Xueli Bai, Qi Zhang, Xingmei Liang, Xinyan Jin, Zeda Zhao, Wei Song, Qian Tan, Ronghua Zhao, William Jia, Shanzhi Gu, Guoming Shi, Ziwei Zheng, Guyue Wei, Youlei Wang, Tian Fang, Yuwei Li, Zijun Wang, Zifan Yang, Sida Guo, Danni Lin, Fang Wei, Lei Wang, Xiaoli Sun, Aijun Qin, Longshen Xie, Yeting Qiu, Wenqing Bao, Shah Rahimian, Manu Singh, Yanal Murad, Jianying Shang, Min Chu, Maoliang Huang, Jun Ding, Wei Chen, Yufu Ye, Yiwen Chen, Xiang Li and Tingbo Liang

Editorial Expression of Concern: Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis pp. E6-E6

Shidong Jia, Zhenning Liu, Sen Zhang, Pixu Liu, Lei Zhang, Sang Hyun Lee, Jing Zhang, Sabina Signoretti, Massimo Loda, Thomas M. Roberts and Jean J. Zhao

Editorial Expression of Concern: A melanocyte lineage program confers resistance to MAP kinase pathway inhibition pp. E7-E7

Cory M. Johannessen, Laura A. Johnson, Federica Piccioni, Aisha Townes, Dennie T. Frederick, Melanie K. Donahue, Rajiv Narayan, Keith T. Flaherty, Jennifer A. Wargo, David E. Root and Levi A. Garraway

Why China needs to review its approach to research evaluation pp. 283-283

Yuxin Zhao

Cuts to US science will take a generation to repair — leaders must speak up now pp. 284-284

Michael S. Lubell

Canada’s election: what Mark Carney’s win means for science pp. 287-288

Nicola Jones

Trump team’s science cuts threaten tenure hopes for early-career academics pp. 288-289

Laura Dattaro

Science sleuths flag hundreds of papers that use AI without disclosing it pp. 290-291

Diana Kwon

Did a tardigrade get the world’s tiniest tattoo? April’s best science images pp. 291-291

Emma Stoye

Major European institutes join race to save US science data pp. 292-293

Jeff Tollefson

Huge reproducibility project fails to validate dozens of biomedical studies pp. 293-294

Rodrigo de Oliveira Andrade

COVID vaccine works faster with both doses in the same arm pp. 294-294

Rachel Fieldhouse

Supportive? Addictive? Abusive? How AI companions affect our mental health pp. 296-298

David Adam

How protein-slayer drugs could beat some of the cruellest cancers pp. 300-302

Ken Garber

Whale earwax, fungal fertilizer and chocolate emissions: exhibition explores biodiversity research pp. 303-304

Chris Simms

Why the green-technology race might not save the planet pp. 305-308

Edward Barbier

Want to supercharge your science? Turn to technicians pp. 308-310

Venkatesh Narayanamurti and Steven C. Currall

Next CERN collider has community input pp. 311-311

Costas Fountas

In science-for-policy design, one size doesn’t fit all pp. 311-311

Mario Scharfbillig, Mara Almeida, Kristian Krieger and Lorenzo Melchor

USAID’s shutdown: a crisis for sub-Saharan Africa pp. 311-311

Mauer Gonçalves and Howard Lopes Ribeiro Junior

Manage releases of ‘forever chemicals’ in lab waste pp. 311-311

Kehan Liu and Cheng Zhang

Complete ape genomes offer a close-up view of human evolution pp. 313-314

Lukas Kuderna

Searching for dark photons in the Sun’s atmosphere pp. 315-315

Katherine Skipper

Climate risk for younger generations is set to soar pp. 315-316

Rosanna Gualdi and Raya Muttarak

Chronic stress drives depression by disrupting cellular housekeeping pp. 317-318

Alberto Corona and Paul J. Kenny

Could the shingles vaccine help to prevent dementia? pp. 318-320

Anupam B. Jena

Nasal vaccines for respiratory infections pp. 321-330

Hiroshi Kiyono and Peter B. Ernst

Using life cycle assessment to drive innovation for sustainable cool clouds pp. 331-338

Husam Alissa, Teresa Nick, Ashish Raniwala, Alberto Arribas Herranz, Kali Frost, Ioannis Manousakis, Kari Lio, Brijesh Warrier, Vaidehi Oruganti, T. J. DiCaprio, Kathryn Oseen-Senda, Bharath Ramakrishnan, Naval Gupta, Ricardo Bianchini, Jim Kleewein, Christian Belady, Marcus Fontoura, Julie Sinistore, Mukunth Natarajan, Lauren Johnson, VeeAnder Mealing, Praneet Arshi and Madeline Frieze

An asymmetric fission island driven by shell effects in light fragments pp. 339-344

P. Morfouace, J. Taieb, A. Chatillon, L. Audouin, G. Blanchon, R. N. Bernard, N. Dubray, N. Pillet, D. Regnier, H. Alvarez-Pol, F. Amjad, P. André, G. Authelet, L. Atar, T. Aumann, J. Benlliure, K. Boretzky, L. Bott, T. Brecelj, C. Caesar, P. Carpentier, E. Casarejos, J. Cederkäll, A. Corsi, D. Cortina-Gil, A. Cvetinović, E. De Filippo, T. Dickel, M. Feijoo, L. M. Fonseca, D. Galaviz, G. García-Jiménez, I. Gasparic, E. I. Geraci, R. Gernhäuser, B. Gnoffo, K. Göbel, A. Graña-González, E. Haettner, A.-L. Hartig, M. Heil, A. Heinz, T. Hensel, M. Holl, C. Hornung, A. Horvat, A. Jedele, D. Jelavic Malenica, T. Jenegger, L. Ji, H. T. Johansson, B. Jonson, B. Jurado, N. Kalantar-Nayestanaki, E. Kazantseva, A. Kelic-Heil, O. A. Kiselev, P. Klenze, R. Knöbel, D. Körper, D. Kostyleva, T. Kröll, N. Kuzminchuk, B. Laurent, I. Lihtar, Yu. A. Litvinov, B. Löher, N. S. Martorana, B. Mauss, S. Murillo Morales, D. Mücher, I. Mukha, E. Nacher, A. Obertelli, E. V. Pagano, V. Panin, J. Park, S. Paschalis, M. Petri, S. Pietri, S. Pirrone, G. Politi, L. Ponnath, A. Revel, H.-B. Rhee, J. L. Rodríguez-Sánchez, L. Rose, D. Rossi, P. Roy, P. Russotto, C. Scheidenberger, H. Scheit, H. Simon, S. Storck-Dutine, A. Stott, Y. L. Sun, C. Sürder, Y. K. Tanaka, R. Taniuchi, O. Tengblad, I. Tisma, H. T. Törnqvist, M. Trimarchi, S. Velardita, J. Vesic, B. Voss, F. Wamers, H. Weick, F. Wienholtz, J. Zhao and M. Zhukov

Quantum twisting microscopy of phonons in twisted bilayer graphene pp. 345-351

J. Birkbeck, J. Xiao, A. Inbar, T. Taniguchi, K. Watanabe, E. Berg, L. Glazman, F. Guinea, F. Oppen and S. Ilani

Intragrain 3D perovskite heterostructure for high-performance pure-red perovskite LEDs pp. 352-357

Yong-Hui Song, Bo Li, Zi-Jian Wang, Xiao-Lin Tai, Guan-Jie Ding, Zi-Du Li, Huaiyu Xu, Jing-Ming Hao, Kuang-Hui Song, Li-Zhe Feng, Ya-Lan Hu, Yi-Chen Yin, Bai-Sheng Zhu, Guozhen Zhang, Huanxin Ju, Guanhaojie Zheng, Wei Hu, Yue Lin, Fengjia Fan and Hong-Bin Yao

Structurally complex phase engineering enables hydrogen-tolerant Al alloys pp. 358-364

Shengyu Jiang, Yuantao Xu, Ruihong Wang, Xinren Chen, Chaoshuai Guan, Yong Peng, Fuzhu Liu, Mingxu Wang, Xu Liu, Shaoyou Zhang, Genqi Tian, Shenbao Jin, Huiyuan Wang, Hiroyuki Toda, Xuejun Jin, Gang Liu, Baptiste Gault and Jun Sun

Sustainable nickel enabled by hydrogen-based reduction pp. 365-373

U. Manzoor, L. Mujica Roncery, D. Raabe and I. R. Souza Filho

Global emergence of unprecedented lifetime exposure to climate extremes pp. 374-379

Luke Grant, Inne Vanderkelen, Lukas Gudmundsson, Erich Fischer, Sonia I. Seneviratne and Wim Thiery

Melt focusing along lithosphere–asthenosphere boundary below Axial volcano pp. 380-387

G. M. Kent, A. F. Arnulf, S. C. Singh, H. Carton, A. J. Harding and S. Saustrup

Pacific hotspots reveal a Louisville–Ontong Java Nui tectonic link pp. 388-394

J. G. Konter, V. A. Finlayson, K. Konrad, M. G. Jackson, A. A. P. Koppers, P. Wessel, S. Beethe, M. Bizimis, A. Alverson and C. Kelley

The global human impact on biodiversity pp. 395-400

François Keck, Tianna Peller, Roman Alther, Cécilia Barouillet, Rosetta Blackman, Eric Capo, Teofana Chonova, Marjorie Couton, Lena Fehlinger, Dominik Kirschner, Mara Knüsel, Lucile Muneret, Rebecca Oester, Kálmán Tapolczai, Heng Zhang and Florian Altermatt

Complete sequencing of ape genomes pp. 401-418

DongAhn Yoo, Arang Rhie, Prajna Hebbar, Francesca Antonacci, Glennis A. Logsdon, Steven J. Solar, Dmitry Antipov, Brandon D. Pickett, Yana Safonova, Francesco Montinaro, Yanting Luo, Joanna Malukiewicz, Jessica M. Storer, Jiadong Lin, Abigail N. Sequeira, Riley J. Mangan, Glenn Hickey, Graciela Monfort Anez, Parithi Balachandran, Anton Bankevich, Christine R. Beck, Arjun Biddanda, Matthew Borchers, Gerard G. Bouffard, Emry Brannan, Shelise Y. Brooks, Lucia Carbone, Laura Carrel, Agnes P. Chan, Juyun Crawford, Mark Diekhans, Eric Engelbrecht, Cedric Feschotte, Giulio Formenti, Gage H. Garcia, Luciana de Gennaro, David Gilbert, Richard E. Green, Andrea Guarracino, Ishaan Gupta, Diana Haddad, Junmin Han, Robert S. Harris, Gabrielle A. Hartley, William T. Harvey, Michael Hiller, Kendra Hoekzema, Marlys L. Houck, Hyeonsoo Jeong, Kaivan Kamali, Manolis Kellis, Bryce Kille, Chul Lee, Youngho Lee, William Lees, Alexandra P. Lewis, Qiuhui Li, Mark Loftus, Yong Hwee Eddie Loh, Hailey Loucks, Jian Ma, Yafei Mao, Juan F. I. Martinez, Patrick Masterson, Rajiv C. McCoy, Barbara McGrath, Sean McKinney, Britta S. Meyer, Karen H. Miga, Saswat K. Mohanty, Katherine M. Munson, Karol Pal, Matt Pennell, Pavel A. Pevzner, David Porubsky, Tamara Potapova, Francisca R. Ringeling, Joana L. Rocha, Oliver A. Ryder, Samuel Sacco, Swati Saha, Takayo Sasaki, Michael C. Schatz, Nicholas J. Schork, Cole Shanks, Linnéa Smeds, Dongmin R. Son, Cynthia Steiner, Alexander P. Sweeten, Michael G. Tassia, Françoise Thibaud-Nissen, Edmundo Torres-González, Mihir Trivedi, Wenjie Wei, Julie Wertz, Muyu Yang, Panpan Zhang, Shilong Zhang, Yang Zhang, Zhenmiao Zhang, Sarah A. Zhao, Yixin Zhu, Erich D. Jarvis, Jennifer L. Gerton, Iker Rivas-González, Benedict Paten, Zachary A. Szpiech, Christian D. Huber, Tobias L. Lenz, Miriam K. Konkel, Soojin V. Yi, Stefan Canzar, Corey T. Watson, Peter H. Sudmant, Erin Molloy, Erik Garrison, Craig B. Lowe, Mario Ventura, Rachel J. O’Neill, Sergey Koren, Kateryna D. Makova, Adam M. Phillippy and Evan E. Eichler

The contribution of de novo coding mutations to meningomyelocele pp. 419-426

Yoo-Jin Jiny Ha, Ashna Nisal, Isaac Tang, Chanjae Lee, Ishani Jhamb, Cassidy Wallace, Robyn Howarth, Sarah Schroeder, Keng Ioi Vong, Naomi Meave, Fiza Jiwani, Chelsea Barrows, Sangmoon Lee, Nan Jiang, Arzoo Patel, Krisha Bagga, Niyati Banka, Liana Friedman, Francisco A. Blanco, Seyoung Yu, Soeun Rhee, Hui Su Jeong, Isaac Plutzer, Michael B. Major, Béatrice Benoit, Christian Poüs, Caleb Heffner, Zoha Kibar, Gyang Markus Bot, Hope Northrup, Kit Sing Au, Madison Strain, Allison E. Ashley-Koch, Richard H. Finnell, Joan T. Le, Hal S. Meltzer, Camila Araujo, Helio R. Machado, Roger E. Stevenson, Anna Yurrita, Sara Mumtaz, Awais Ahmed, Mulazim Hussain Khara, Osvaldo M. Mutchinick, José Ramón Medina-Bereciartu, Friedhelm Hildebrandt, Gia Melikishvili, Ahmed I. Marwan, Valeria Capra, Mahmoud M. Noureldeen, Aida M. S. Salem, Mahmoud Y. Issa, Maha S. Zaki, Libin Xu, Ji Eun Lee, Donghyuk Shin, Anna Alkelai, Alan R. Shuldiner, Stephen F. Kingsmore, Stephen A. Murray, Heon Yung Gee, W. Todd Miller, Kimberley F. Tolias, John B. Wallingford, Sangwoo Kim and Joseph G. Gleeson

Stress dynamically modulates neuronal autophagy to gate depression onset pp. 427-437

Liang Yang, Chen Guo, Zhiwei Zheng, Yiyan Dong, Qifeng Xie, Zijian Lv, Min Li, Yangyang Lu, Xiaonan Guo, Rongshan Deng, Yiqin Liu, Yirong Feng, Ruiqi Mu, Xuliang Zhang, Huan Ma, Zhong Chen, Zhijun Zhang, Zhaoqi Dong, Wei Yang, Xiangnan Zhang and Yihui Cui

A natural experiment on the effect of herpes zoster vaccination on dementia pp. 438-446

Markus Eyting, Min Xie, Felix Michalik, Simon Heß, Seunghun Chung and Pascal Geldsetzer

Evolution of temperature preference in flies of the genus Drosophila pp. 447-455

Matthew Capek, Oscar M. Arenas, Michael H. Alpert, Emanuela E. Zaharieva, Iván D. Méndez-González, José Miguel Simões, Hamin Gil, Aldair Acosta, Yuqing Su, Alessia Para and Marco Gallio

Bifidobacteria support optimal infant vaccine responses pp. 456-464

Feargal J. Ryan, Michelle Clarke, Miriam A. Lynn, Saoirse C. Benson, Sonia McAlister, Lynne C. Giles, Jocelyn M. Choo, Charné Rossouw, Yan Yung Ng, Evgeny A. Semchenko, Alyson Richard, Lex E. X. Leong, Steven L. Taylor, Stephen J. Blake, Joyce I. Mugabushaka, Mary Walker, Steve L. Wesselingh, Paul V. Licciardi, Kate L. Seib, Damon J. Tumes, Peter Richmond, Geraint B. Rogers, Helen S. Marshall and David J. Lynn

Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium pp. 465-475

Hans Schoofs, Nina Daubel, Sarah Schnabellehner, Max L. B. Grönloh, Sebastián Palacios Martínez, Aleksi Halme, Amanda M. Marks, Marie Jeansson, Sara Barcos, Cord Brakebusch, Rui Benedito, Britta Engelhardt, Dietmar Vestweber, Konstantin Gaengel, Fabian Linsenmeier, Sebastian Schürmann, Pipsa Saharinen, Jaap D. Buul, Oliver Friedrich, Richard S. Smith, Mateusz Majda and Taija Mäkinen

Sensing ceramides by CYSLTR2 and P2RY6 to aggravate atherosclerosis pp. 476-485

Siting Zhang, Hui Lin, Jiale Wang, Jingyu Rui, Tengwei Wang, Zeyu Cai, Shenming Huang, Yanxiang Gao, Tianfeng Ma, Rui Fan, Rongbo Dai, Zhiqing Li, Yiting Jia, Qiang Chen, HaoMing He, Jiaai Tan, Shirong Zhu, Rui Gu, Zhigang Dong, Meihong Li, Enmin Xie, Yi Fu, Jingang Zheng, Changtao Jiang, Jinpeng Sun and Wei Kong

Transient silencing of hypermutation preserves B cell affinity during clonal bursting pp. 486-494

Juhee Pae, Niklas Schwan, Bertrand Ottino-Loffler, William S. DeWitt, Amar Garg, Juliana Bortolatto, Ashni A. Vora, Jin-Jie Shen, Alvaro Hobbs, Tiago B. R. Castro, Luka Mesin, Frederick A. Matsen, Michael Meyer-Hermann and Gabriel D. Victora

Regulated somatic hypermutation enhances antibody affinity maturation pp. 495-502

Julia Merkenschlager, Andrew G. T. Pyo, Gabriela S. Silva Santos, Dennis Schaefer-Babajew, Melissa Cipolla, Harald Hartweger, Alexander D. Gitlin, Ned S. Wingreen and Michel C. Nussenzweig

Oncolytic virus VG161 in refractory hepatocellular carcinoma pp. 503-511

Yinan Shen, Xueli Bai, Qi Zhang, Xingmei Liang, Xinyan Jin, Zeda Zhao, Wei Song, Qian Tan, Ronghua Zhao, William Jia, Shanzhi Gu, Guoming Shi, Ziwei Zheng, Guyue Wei, Youlei Wang, Tian Fang, Yuwei Li, Zijun Wang, Zifan Yang, Sida Guo, Danni Lin, Fang Wei, Lei Wang, Xiaoli Sun, Aijun Qin, Longshen Xie, Yeting Qiu, Wenqing Bao, Shah Rahimian, Manu Singh, Yanal Murad, Jianying Shang, Min Chu, Maoliang Huang, Jun Ding, Wei Chen, Yufu Ye, Yiwen Chen, Xiang Li and Tingbo Liang

The RAD52 double-ring remodels replication forks restricting fork reversal pp. 512-519

Masayoshi Honda, Mortezaali Razzaghi, Paras Gaur, Eva Malacaria, Giorgia Marozzi, Ludovica Di Biagi, Francesca Antonella Aiello, Emeleeta A. Paintsil, Andrew J. Stanfield, Bailey J. Deppe, Lokesh Gakhar, Nicholas J. Schnicker, M. Ashley Spies, Pietro Pichierri and Maria Spies

Snapshots of acyl carrier protein shuttling in human fatty acid synthase pp. 520-528

Kollin Schultz, Pedro Costa-Pinheiro, Lauren Gardner, Laura V. Pinheiro, Julio Ramirez-Solis, Sarah M. Gardner, Kathryn E. Wellen and Ronen Marmorstein

Structural dynamics of human fatty acid synthase in the condensing cycle pp. 529-536

Wooyoung Choi, Chengmin Li, Yifei Chen, YongQiang Wang and Yifan Cheng

GluA2-containing AMPA receptors form a continuum of Ca2+-permeable channels pp. 537-544

Federico Miguez-Cabello, Xin-tong Wang, Yuhao Yan, Niklas Brake, Ryan P. D. Alexander, Amanda M. Perozzo, Anmar Khadra and Derek Bowie

Can Germany rein in its academic bullying problem? pp. 545-547

Virginia Gewin

Walking in two worlds: how an Indigenous computer scientist is using AI to preserve threatened languages pp. 548-550

Amanda Heidt

I climb mountains in search of sustainable agricultural systems pp. 552-552

James Mitchell Crow

2025, volume 641, articles 8061

Author Correction: Sulfide-rich continental roots at cratonic margins formed by carbonated melts pp. E1-E1

Chunfei Chen, Michael W. Förster, Svyatoslav S. Shcheka, Isra S. Ezad, Joshua J. Shea, Yongsheng Liu, Dorrit E. Jacob and Stephen F. Foley

Academia needs a more honest, scientific approach to DEI pp. 9-9

Keon West

Inside the quest to digitally unroll ancient scrolls burnt by Vesuvius pp. 13-15

Jo Marchant

Invasion of the ‘journal snatchers’: the firms that buy science publications and turn them rogue pp. 15-16

Dalmeet Singh Chawla

Brand-new colour created by tricking human eyes with laser pp. 16-17

Elizabeth Gibney

25 million deaths: what could happen if the US ends global health funding pp. 17-18

Smriti Mallapaty

‘Totally broken’: how Trump 2.0 has paralysed work at US science agencies pp. 18-20

Dan Garisto and Jeff Tollefson

Century-old genetics mystery of Mendel’s peas finally solved pp. 20-20

Amanda Heidt

Trump blew up the global fight against AIDS. Can it recover? pp. 22-25

Simar S. Bajaj

Will US science survive Trump 2.0? pp. 26-30

Jeff Tollefson, Dan Garisto and Heidi Ledford

How the world’s largest language family spread — and why others go extinct pp. 31-33

Andrew Robinson

The lunatic is on the grass: Books in brief pp. 33-33

Andrew Robinson

Why we need to measure people’s well-being — lessons from a global survey pp. 34-36

Tyler J. VanderWeele and Byron R. Johnson

Eugenics is on the rise again: human geneticists must take a stand pp. 37-38

Genevieve L. Wojcik

The use of AI in peer review could undermine science pp. 39-39

Md Doulotuzzaman Xames

Preserve access to crucial climate data pp. 39-39

Juan A. Añel

Cell classification should be based on more than just DNA pp. 39-39

Howard Lopes Ribeiro Junior

Debris from rockets is polluting the Caribbean pp. 39-39

Kristal K. Ambrose and Tony R. Walker

Rare ancient DNA from Sahara opens a window on the region’s verdant past pp. 41-43

Mary Prendergast

Metal-cored molecule is the first of its kind pp. 43-44

Rebecca Musgrave

Crucial meeting: molecule helps vaccine to interact with killer T cells pp. 44-46

John T. Wilson

Hunter-gatherers journeyed by sea to Malta pp. 46-47

Dylan Gaffney

Twenty years of genome-wide association studies pp. 47-49

Lorraine Southam and Eleftheria Zeggini

The distribution of subsurface microplastics in the ocean pp. 51-61

Shiye Zhao, Karin F. Kvale, Lixin Zhu, Erik R. Zettler, Matthias Egger, Tracy J. Mincer, Linda A. Amaral-Zettler, Laurent Lebreton, Helge Niemann, Ryota Nakajima, Martin Thiel, Ryan P. Bos, Luisa Galgani and Aron Stubbins

Observation of the axion quasiparticle in 2D MnBi2Te4 pp. 62-69

Jian-Xiang Qiu, Barun Ghosh, Jan Schütte-Engel, Tiema Qian, Michael Smith, Yueh-Ting Yao, Junyeong Ahn, Yu-Fei Liu, Anyuan Gao, Christian Tzschaschel, Houchen Li, Ioannis Petrides, Damien Bérubé, Thao Dinh, Tianye Huang, Olivia Liebman, Emily M. Been, Joanna M. Blawat, Kenji Watanabe, Takashi Taniguchi, Kin Chung Fong, Hsin Lin, Peter P. Orth, Prineha Narang, Claudia Felser, Tay-Rong Chang, Ross McDonald, Robert J. McQueeney, Arun Bansil, Ivar Martin, Ni Ni, Qiong Ma, David J. E. Marsh, Ashvin Vishwanath and Su-Yang Xu

Antiferromagnetic quantum anomalous Hall effect under spin flips and flops pp. 70-75

Zichen Lian, Yongchao Wang, Yongqian Wang, Wen-Han Dong, Yang Feng, Zehao Dong, Mangyuan Ma, Shuai Yang, Liangcai Xu, Yaoxin Li, Bohan Fu, Yuetan Li, Wanjun Jiang, Yong Xu, Chang Liu, Jinsong Zhang and Yayu Wang

Electric-field-induced domain walls in wurtzite ferroelectrics pp. 76-82

Ding Wang, Danhao Wang, Mahlet Molla, Yujie Liu, Samuel Yang, Shuaishuai Yuan, Jiangnan Liu, Mingtao Hu, Yuanpeng Wu, Tao Ma, Kai Sun, Hong Guo, Emmanouil Kioupakis and Zetian Mi

Driven bright solitons on a mid-infrared laser chip pp. 83-89

Dmitry Kazakov, Theodore P. Letsou, Marco Piccardo, Lorenzo L. Columbo, Massimo Brambilla, Franco Prati, Sandro Dal Cin, Maximilian Beiser, Nikola Opačak, Pawan Ratra, Michael Pushkarsky, David Caffey, Timothy Day, Luigi A. Lugiato, Benedikt Schwarz and Federico Capasso

Subnanosecond flash memory enabled by 2D-enhanced hot-carrier injection pp. 90-97

Yutong Xiang, Chong Wang, Chunsen Liu, Tanjun Wang, Yongbo Jiang, Yang Wang, Shuiyuan Wang and Peng Zhou

Atomic lift-off of epitaxial membranes for cooling-free infrared detection pp. 98-105

Xinyuan Zhang, Owen Ericksen, Sangho Lee, Marx Akl, Min-Kyu Song, Haihui Lan, Pratap Pal, Jun Min Suh, Shane Lindemann, Jung-El Ryu, Yanjie Shao, Xudong Zheng, Ne Myo Han, Bikram Bhatia, Hyunseok Kim, Hyun S. Kum, Celesta S. Chang, Yunfeng Shi, Chang-Beom Eom and Jeehwan Kim

Metal-centred planar [15]annulenes pp. 106-111

Binbin Xu, Dafa Chen, Kaidong Ruan, Ming Luo, Yuanting Cai, Jia Qiu, Wenhao Zhou, Bula Cao, Zhenyang Lin, Jonathan L. Sessler and Haiping Xia

Generalizing arene C–H alkylations by radical–radical cross-coupling pp. 112-121

Johannes Großkopf, Chawanansaya Gopatta, Robert T. Martin, Alexander Haseloer and David W. C. MacMillan

Effects of glacial forcing on lithospheric motion and ridge spreading pp. 122-128

Tao Yuan and Shijie Zhong

Canopy functional trait variation across Earth’s tropical forests pp. 129-136

Jesús Aguirre-Gutiérrez, Sami W. Rifai, Xiongjie Deng, Hans Steege, Eleanor Thomson, Jose Javier Corral-Rivas, Aretha Franklin Guimaraes, Sandra Muller, Joice Klipel, Sophie Fauset, Angelica F. Resende, Göran Wallin, Carlos A. Joly, Katharine Abernethy, Stephen Adu-Bredu, Celice Alexandre Silva, Edmar Almeida Oliveira, Danilo R. A. Almeida, Esteban Alvarez-Davila, Gregory P. Asner, Timothy R. Baker, Maíra Benchimol, Lisa Patrick Bentley, Erika Berenguer, Lilian Blanc, Damien Bonal, Kauane Bordin, Robson Borges de Lima, Sabine Both, Jaime Cabezas Duarte, Domingos Cardoso, Haroldo C. de Lima, Larissa Cavalheiro, Lucas A. Cernusak, Nayane Cristina C. Santos Prestes, Antonio Carlos Silva Zanzini, Ricardo José Silva, Robson Santos Alves da Silva, Mariana Andrade Iguatemy, Tony César Sousa Oliveira, Benjamin Dechant, Géraldine Derroire, Kyle G. Dexter, Domingos J. Rodrigues, Mário Espírito-Santo, Letícia Fernandes Silva, Tomas Ferreira Domingues, Joice Ferreira, Marcelo Fragomeni Simon, Cécile A. J. Girardin, Bruno Hérault, Kathryn J. Jeffery, Sreejith Kalpuzha Ashtamoorthy, Arunkumar Kavidapadinjattathil Sivadasan, Bente Klitgaard, William F. Laurance, Maurício Lima Dan, William E. Magnusson, Eduardo Malta Campos-Filho, Rubens Manoel dos Santos, Angelo Gilberto Manzatto, Marcos Silveira, Ben Hur Marimon-Junior, Roberta E. Martin, Daniel Luis Mascia Vieira, Thiago Metzker, William Milliken, Peter Moonlight, Marina Maria Moraes de Seixas, Paulo S. Morandi, Robert Muscarella, María Guadalupe Nava-Miranda, Brigitte Nyirambangutse, Jhonathan Oliveira Silva, Imma Oliveras Menor, Pablo José Francisco Pena Rodrigues, Cinthia Pereira de Oliveira, Lucas Pereira Zanzini, Carlos A. Peres, Vignesh Punjayil, Carlos A. Quesada, Maxime Réjou-Méchain, Terhi Riutta, Gonzalo Rivas-Torres, Clarissa Rosa, Norma Salinas, Rodrigo Scarton Bergamin, Beatriz Schwantes Marimon, Alexander Shenkin, Priscyla Maria Silva Rodrigues, Axa Emanuelle Simões Figueiredo, Queila Souza Garcia, Tereza Spósito, Danielle Storck-Tonon, Martin J. P. Sullivan, Martin Svátek, Wagner Tadeu Vieira Santiago, Yit Arn Teh, Prasad Theruvil Parambil Sivan, Marcelo Trindade Nascimento, Elmar Veenendaal, Irie Casimir Zo-Bi, Marie Ruth Dago, Soulemane Traoré, Marco Patacca, Vincyane Badouard, Samuel Padua Chaves e Carvalho, Lee J. T. White, Huanyuan Zhang-Zheng, Etienne Zibera, Joeri Alexander Zwerts, David F. R. P. Burslem, Miles Silman, Jérôme Chave, Brian J. Enquist, Jos Barlow, Oliver L. Phillips, David A. Coomes and Yadvinder Malhi

Hunter-gatherer sea voyages extended to remotest Mediterranean islands pp. 137-143

Eleanor M. L. Scerri, James Blinkhorn, Huw S. Groucutt, Mathew Stewart, Ian Candy, Ethel Allué, Aitor Burguet-Coca, Andrés Currás, W. Christopher Carleton, Susanne Lindauer, Robert Spengler, Kseniia Boxleitner, Gillian Asciak, Margherita Colucci, Ritienne Gauci, Amy Hatton, Johanna Kutowsky, Andreas Maier, Mario Mata-González, Nicolette Mifsud, Khady Niang, Patrick Roberts, Joshua Giorgio, Rochelle Xerri and Nicholas C. Vella

Ancient DNA from the Green Sahara reveals ancestral North African lineage pp. 144-150

Nada Salem, Marieke S. Loosdrecht, Arev Pelin Sümer, Stefania Vai, Alexander Hübner, Benjamin Peter, Raffaela A. Bianco, Martina Lari, Alessandra Modi, Mohamed Faraj Mohamed Al-Faloos, Mustafa Turjman, Abdeljalil Bouzouggar, Mary Anne Tafuri, Giorgio Manzi, Rocco Rotunno, Kay Prüfer, Harald Ringbauer, David Caramelli, Savino Lernia and Johannes Krause

A subcortical switchboard for perseverative, exploratory and disengaged states pp. 151-161

Mehran Ahmadlou, Maryam Yasamin Shirazi, Pan Zhang, Isaac L. M. Rogers, Julia Dziubek, Margaret Young and Sonja B. Hofer

Brain-wide presynaptic networks of functionally distinct cortical neurons pp. 162-172

Ana R. Inácio, Ka Chun Lam, Yuan Zhao, Francisco Pereira, Charles R. Gerfen and Soohyun Lee

Perception of viral infections and initiation of antiviral defence in rice pp. 173-181

Yu Huang, Jialin Yang, Xi Sun, Jiahao Li, Xiaoqiang Cao, Shengze Yao, Yanhong Han, Changtian Chen, Linlin Du, Shuo Li, Yinghua Ji, Tong Zhou, He Wang, Jia-jia Han, Wenming Wang, Chunhong Wei, Qi Xie, Zhirui Yang and Yi Li

Brief antibiotic use drives human gut bacteria towards low-cost resistance pp. 182-191

Eitan Yaffe, Les Dethlefsen, Arati V. Patankar, Chen Gui, Susan Holmes and David A. Relman

Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide pp. 192-201

Laetitia Coassolo, Niels B. Danneskiold-Samsøe, Quennie Nguyen, Amanda Wiggenhorn, Meng Zhao, David Cheng-Hao Wang, David Toomer, Jameel Lone, Yichao Wei, Aayan Patel, Irene Liparulo, Deniz Kavi, Lianna W. Wat, Saranya Chidambaranathan Reghupaty, Julie Jae Kim, Tina Asemi, Ewa Bielczyk-Maczynska, Veronica L. Li, Maria Dolores Moya-Garzon, Nicole A. J. Krentz, Andreas Stahl, Danny Hung-Chieh Chou, Liqun Luo and Katrin J. Svensson

STING agonist-based ER-targeting molecules boost antigen cross-presentation pp. 202-210

Xiafeng Wang, Zhangping Huang, Lixiao Xing, Liru Shang, Juan Jiang, Caiguanxi Deng, Wei Yu, Lin Peng, Hao Yang, Xiaohong Zheng, Xinmin Liu, Haolan Yang, Yixin Chen, Yongyong Li, Jing Liu, Xi Xie, Wei Xu, Xiaojun Xia, Zezhong Liu, Wanli Liu, Shibo Jiang, Yingyue Zeng, Lu Lu and Ji Wang

Granzyme K activates the entire complement cascade pp. 211-221

Carlos A. Donado, Erin Theisen, Fan Zhang, Aparna Nathan, Madison L. Fairfield, Karishma Vijay Rupani, Dominique Jones, Kellsey P. Johannes, Soumya Raychaudhuri, Daniel F. Dwyer, A. Helena Jonsson and Michael B. Brenner

Brain-wide neuronal circuit connectome of human glioblastoma pp. 222-231

Yusha Sun, Xin Wang, Daniel Y. Zhang, Zhijian Zhang, Janardhan P. Bhattarai, Yingqi Wang, Kristen H. Park, Weifan Dong, Yun-Fen Hung, Qian Yang, Feng Zhang, Keerthi Rajamani, Shang Mu, Benjamin C. Kennedy, Yan Hong, Jamie Galanaugh, Abhijeet Sambangi, Sang Hoon Kim, Garrett Wheeler, Tiago Gonçalves, Qing Wang, Daniel H Geschwind, Riki Kawaguchi, Angela N. Viaene, Ingo Helbig, Sudha K. Kessler, Ahmet Hoke, Huadong Wang, Fuqiang Xu, Zev A. Binder, H. Isaac Chen, Emily Ling-Lin Pai, Sara Stone, MacLean P. Nasrallah, Kimberly M. Christian, Marc Fuccillo, Nicolas Toni, Zhuhao Wu, Hwai-Jong Cheng, Donald M. O’Rourke, Minghong Ma, Guo-li Ming and Hongjun Song

Sleep pressure accumulates in a voltage-gated lipid peroxidation memory pp. 232-239

H. Olof Rorsman, Max A. Müller, Patrick Z. Liu, Laura Garmendia Sanchez, Anissa Kempf, Stefanie Gerbig, Bernhard Spengler and Gero Miesenböck

Structural dynamics of DNA unwinding by a replicative helicase pp. 240-249

Taha Shahid, Ammar U. Danazumi, Muhammad Tehseen, Lubna Alhudhali, Alice R. Clark, Christos G. Savva, Samir M. Hamdan and Alfredo De Biasio

Structure of mitochondrial pyruvate carrier and its inhibition mechanism pp. 250-257

Zheng He, Jianxiu Zhang, Yan Xu, Eve J. Fine, Carl-Mikael Suomivuori, Ron O. Dror and Liang Feng

Structures and mechanism of the human mitochondrial pyruvate carrier pp. 258-265

Jiaming Liang, Junhui Shi, Ailong Song, Meihua Lu, Kairan Zhang, Meng Xu, Gaoxingyu Huang, Peilong Lu, Xudong Wu and Dan Ma

My fight to unlock cannabis and psychedelic drugs for use in medical research pp. 267-269

Robin Berghaus

The do’s and don’ts of scientific image editing pp. 270-271

Sara Reardon

A forensic investigator of glacier change pp. 274-274

Raveena Bhambra