AI language and emotional support as a physician assistant in hypertension management: an N-of-1 case study on virtual encouragement and blood pressure control

Abdullah Al Fraidan ()
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Abdullah Al Fraidan: King Faisal University

Palgrave Communications, 2025, vol. 12, issue 1, 1-11

Abstract: Abstract This study explores the role of an AI assistant in supporting hypertension management by providing both emotional and behavioral reinforcement. Over a 90-day period, the participant documented interactions with the AI, focusing on its impact on emotional well-being, adherence to health routines, and blood pressure regulation. The AI assistant employed empathetic language, real-time behavioral guidance, and personalized health recommendations to foster trust, alleviate emotional distress, and encourage consistent self-monitoring. Statistical analysis revealed a significant reduction in systolic and diastolic blood pressure over time, with AI-assisted interventions such as breathing exercises and guided meditation leading to immediate and measurable improvements. Correlation analysis further demonstrated that higher AI engagement was associated with greater reductions in blood pressure. The findings validate psychological and behavioral frameworks such as the Helping Skills Theory and Self-Determination Theory, highlighting the AI’s role in promoting intrinsic motivation, self-efficacy, and adherence to hypertension management strategies. While AI cannot yet fully replicate human emotional intelligence, this study suggests that AI-driven emotional and behavioral reinforcement can serve as an effective adjunct to traditional healthcare. The results underscore the need for future AI development to integrate advanced contextual learning algorithms and multimodal adaptive capabilities to enhance real-time personalization and responsiveness in chronic disease management. The implications of AI-assisted health interventions for scalability, patient engagement, and hybrid AI-human healthcare models are discussed.

Date: 2025
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DOI: 10.1057/s41599-025-05635-9

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