Adopting complementary and integrative medicine: Effects of Antox® and Bactofort® administrations on clinico-pathological changes in pullets inoculated with a very virulent infectious bursal disease virus

Aliyu Danlami Andamin (), Ochuko Orakpoghenor (), Talatu Patience Markus (), Felix Tertsua Akade (), Paul Ayuba Abdu () and Tagang Aluwong ()

International Journal of Veterinary Sciences Research, 2023, vol. 8, issue 1, 17-26

Abstract: This study evaluated the ameliorative effects of Antox® and Bactofort® on clinico-pathological changes in ISA Brown chicks inoculated with a very virulent infectious bursal disease virus (vvIBDV). Two hundred (200) ISA Brown day-old chicks were randomly assigned into four groups (A to D) of 50 birds each. Groups A, and B were administered with Antox®, and Bactofort®, respectively from day-old to 42 days of age, and inoculated with vvIBDV at 28 days of age. Groups C, and D served as positive, and negative controls, respectively. Clinical signs, morbidity and mortality rates, gross and histopathological changes were determined. The clinical signs were moderate in groups A and B, but severe in group C and absent in group D by 7 days post-inoculation (dpi). Morbidity and mortality rates were lower in groups A and B compared to C. Gross and histopathological lesions were less severe in groups A and B compared to C. Antox® and Bactofort® ameliorated the negative effects of vvIBDV. Antox® and Bactofort® could be recommended for use in vvIBDV outbreaks to ameliorate the negative effects due to the infection.

Keywords: Antox®; Bactofort®; Clinical signs; ISA brown chicks; Lesions; vvIBDV. (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:pkp:ijovsr:v:8:y:2023:i:1:p:17-26:id:3394

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