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PLOS Biology

2003 - 2025

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Volume 23, issue 10, 2025

Nicotine induces abnormal motor coupling through sensitization of a mechanosensory circuit in Caenorhabditis elegans pp. 1-27 Downloads
Yuting Liu, Leiru Huang, Ruipeng Wang, Fukang Qi, Yiwen Liu, Qingyuan Chen, Morgane Mialon, Lili Chen, Berangere Pinan-Lucarre and Shangbang Gao
Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors pp. 1-26 Downloads
Aurore A Perrault, Valeria Kebets, Nicole M Y Kuek, Nathan E Cross, Rackeb Tesfaye, Florence B Pomares, Jingwei Li, Michael W L Chee, Thien Thanh Dang-Vu and B T Thomas Yeo

Volume 23, issue 9, 2025

Developmental auditory deprivation in one ear impairs brainstem binaural processing and reduces spatial hearing acuity pp. 1-34 Downloads
Kelsey L Anbuhl, Alexander T Ferber, Andrew D Brown, Victor Benichoux, Nathaniel T Greene and Daniel J Tollin
Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms pp. 1-19 Downloads
Paul B Conway, Livia Autore, Andrea Muñoz Zamora, Antoine Harel, Zijun Wang, Armn A Tavallaei, Stephen M Winston, Clara Ortega- de San Luis, James D O’Leary, Mark A Brimble, Gisella Vetere and Tomás J Ryan
Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex pp. 1-32 Downloads
Joon Ho Choi, Sungwon Bae, Jiho Park, Minsu Yoo, Chul Hoon Kim, Lukas Ian Schmitt, Youngbin Tchoe, Dongil Chung, Ji-Woong Choi and Jong-Cheol Rah
Quantitative modeling of multi-signal quorum-sensing maps environment to bacterial regulatory responses pp. 1-18 Downloads
Stephen Thomas, Ayatollah S El-Zayat, James Gurney, Jennifer Rattray and Sam P Brown
Ending publication bias: A values-based approach to surface null and negative results pp. 1-10 Downloads
Stephen Curry, Eunice Mercado-Lara, Virginia Arechavala-Gomeza, C Glenn Begley, Christophe Bernard, René Bernard, Stefano Bertuzzi, Needhi Bhalla, Dawn Bowers, Samuel Brod, Christopher Chambers, Michael R Dougherty, Yensi Flores Bueso, Stefânia Forner, Alexandra L J Freeman, Magali Haas, Darla P Henderson, Kanika Khanna, Rebecca Lawrence, Kif Liakath-Ali, Christine Liu, Neil Malhotra, José G Merino, Edward Miguel, Rachel Miles, Mary Munson, Shinichi Nakagawa, Robert Nobles, Joy Owango, Michel Tuan Pham, Gina Poe, Alexandra N Ramirez, Sarvenaz Sarabipour, Jill L Silverman, Laura N Smith, P Sriramarao, Paul W Sternberg, Geeta K Swamy, Malú Gámez Tansey, Gonzalo E Torres, Erick H Turner, Lauren von Klinggraeff and Frances Weis-Garcia
Language, economic and gender disparities widen the scientific productivity gap pp. 1-13 Downloads
Tatsuya Amano, Valeria Ramírez-Castañeda, Violeta Berdejo-Espinola, Israel Borokini, Shawan Chowdhury, Marina Golivets, Juan David González-Trujillo, Flavia Montaño-Centellas, Kumar Paudel, Rachel L White and Diogo Veríssimo
The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms pp. 1-35 Downloads
Mohammad Nafees Ansari, Somesh K Jha, Ali Khan, Kajal Rajput, Nishant Pandey, Dolly Jain, Rajeshwari Tripathi, Nihal Medatwal, Pankaj Sharma, Sudeshna Datta, Animesh Kar, Trishna Pani, Sk Asif Ali, Kaushavi Cholke, Kajal Rana, Valiya P Snijesh, Geetashree Mukherjee, Suryanarayana V S Deo, Soumen Basak, Ashutosh Mishra, Jyothi S Prabhu, Arnab Mukhopadhyay, Avinash Bajaj and Ujjaini Dasgupta
Continuous monitoring and machine vision reveals that developing gerbils exhibit structured social behaviors prior to the emergence of autonomy pp. 1-22 Downloads
Catalin Mitelut, Marielisa Diez Castro, Ralph E Peterson, Maria Gonçalves, Jennifer Li, Madeline Gamer, Simon RO Nilsson, Talmo D Pereira and Dan H Sanes
Transformative change to address biodiversity loss is urgent and possible pp. 1-4 Downloads
Anne Larigauderie, Karen O’Brien, Lucas A Garibaldi and Arun Agrawal
Recent extinctions of plant and animal genera are rare, localized, and decelerated pp. 1-17 Downloads
John J Wiens and Kristen E Saban

Volume 23, issue 8, 2025

Recurrence affects the geometry of visual representations across the ventral visual stream in the human brain pp. 1-30 Downloads
Siying Xie, Johannes Singer, Bati Yilmaz, Daniel Kaiser and Radoslaw M Cichy
The prefrontal cortex encodes task-identity information and flexibly adjusts its sensory processes as a function of the specific ongoing task pp. 1-25 Downloads
A Mouille, C Gaillard, E Astrand, C Wardak, Amengual Jl and S Ben Hamed
Active DNA demethylation upstream of rod-photoreceptor fate determination is required for retinal development pp. 1-36 Downloads
Ismael Hernández-Núñez, Alaina Urman, Xiaodong Zhang, William Jacobs, Christy Hoffmann, Ellen G Harding, Shiming Chen, Meelad M Dawlaty, Philip A Ruzycki, John R Edwards and Brian S Clark
Compare first, evaluate later: Upending the neuroscience of choice pp. 1-4 Downloads
Benjamin Y Hayden
Flexible competency framework: A tool for optimizing life science training pp. 1-6 Downloads
Xiuqi Li, Jelena Patrnogić and David Van Vactor
Mitochondrial ROS and HIF-1α signaling mediate synaptic plasticity in the critical period pp. 1-26 Downloads
Daniel Sobrido-Cameán, Bramwell Coulson, Michael Miller, Matthew C W Oswald, Tom Pettini, David M D Bailey, Richard A Baines and Matthias Landgraf

Volume 23, issue 7, 2025

Challenges and opportunities for the next generation of computational tumor models pp. 1-4 Downloads
Lance L Munn and Rakesh K Jain
Omics datasets can bridge the gap between tumor biology and patient care pp. 1-4 Downloads
Ji-Ting Huang, Lei-Jie Dai, Ding Ma and Zhi-Ming Shao
Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan pp. 1-43 Downloads
Asa Farahani, Zhen-Qi Liu, Eric G Ceballos, Justine Y Hansen, Karl Wennberg, Yashar Zeighami, Mahsa Dadar, Claudine J Gauthier, Alain Dagher and Bratislav Misic
Mediator complex subunit MED23 dampens antiviral innate immunity by restricting RIG-I expression pp. 1-21 Downloads
Xiong De-fei, Yi-yang Zhang, Zhi-chao Wang, Yuan-ming Zheng, Han-qing Zhang and Gang Wang
Personalised regional modelling predicts tau progression in the human brain pp. 1-25 Downloads
Pavanjit Chaggar, Jacob Vogel, Alexa Pichet Binette, Travis B Thompson, Olof Strandberg, Niklas Mattsson-Carlgren, Linda Karlsson, Erik Stomrud, Saad Jbabdi, Stefano Magon, Gregory Klein, with the Alzheimer’s Disease Neuroimaging Initiative, Oskar Hansson and Alain Goriely
Goal-directed navigation in humans and deep reinforcement learning agents relies on an adaptive mix of vector-based and transition-based strategies pp. 1-33 Downloads
Denis C L Lan, Laurence T Hunt and Christopher Summerfield
Wakefulness can be distinguished from general anesthesia and sleep in flies using a massive library of univariate time series analyses pp. 1-32 Downloads
Angus Leung, Ahmed Mahmoud, Travis Jeans, Ben D Fulcher, Bruno van Swinderen and Naotsugu Tsuchiya
H3K4me2 distinguishes a distinct class of enhancers during the maternal-to-zygotic transition pp. 1-27 Downloads
Matthew D Hurton, Jennifer M Miller and Miler T Lee

Volume 23, issue 6, 2025

Gnb5 is a negative regulator of the BACE1-mediated Aβ generation and ameliorates cognitive deficits in a mouse model of Alzheimer’s disease pp. 1-21 Downloads
Shaokun Chen, Jiechao Zhou, Shuzhong Wang, Erqu Chen, Kai Zhuang, Raozhou Lin, Chensi Liang, Dan Can, Huifang Li, Jing Li and Jie Zhang
Human attention-guided visual perception is governed by rhythmic oscillations and aperiodic timescales pp. 1-18 Downloads
Isabel Raposo, Ian C Fiebelkorn, Jack J Lin, Josef Parvizi, Sabine Kastner, Robert T Knight, Assaf Breska and Randolph F Helfrich
Adaptive landscapes unveil the complex evolutionary path from sprawling to upright forelimb function and posture in mammals pp. 1-27 Downloads
Robert J Brocklehurst, Magdalen Mercado, Kenneth D Angielczyk and Stephanie E Pierce
Precise spike-timing information in the brainstem is well aligned with the needs of communication and the perception of environmental sounds pp. 1-33 Downloads
Chris Scholes, Stephen Coombes, Alan R Palmer, William S Rhode, Rob Mill and Christian J Sumner
Using anti-DEI policies to dismantle education: A new front in a really old battle pp. 1-3 Downloads
Cissy J Ballen, Terry McGlynn and Kelly R Zamudio
The fifth era of science: Artificial scientific intelligence pp. 1-4 Downloads
Nina Miolane
Too poor to science: How wealth determines who succeeds in STEM pp. 1-4 Downloads
Craig R McClain

Volume 23, issue 5, 2025

Loss of neuropeptidergic regulation of cholinergic transmission induces homeostatic compensation in muscle cells to preserve synaptic strength pp. 1-29 Downloads
Jiajie Shao, Jana F Liewald, Wagner Steuer Costa, Christiane Ruse, Jens Gruber, Mohammad S Djamshedzad, Wulf Gebhardt and Alexander Gottschalk
Explosion of formulaic research articles, including inappropriate study designs and false discoveries, based on the NHANES US national health database pp. 1-15 Downloads
Tulsi Suchak, Anietie E Aliu, Charlie Harrison, Reyer Zwiggelaar, Nophar Geifman and Matt Spick
Predictable motion is progressively extrapolated across temporally distinct processing stages in the human visual cortex pp. 1-23 Downloads
William Turner, Charlie Sexton, Philippa A Johnson, Ella Wilson and Hinze Hogendoorn
Rewarding animals based on their subjective percepts is enabled by online Bayesian estimation of perceptual biases pp. 1-37 Downloads
Yelin Dong, Gabor Lengyel, Sabyasachi Shivkumar, Akiyuki Anzai, Grace F DiRisio, Ralf M Haefner and Gregory C DeAngelis
Is pathogen prediction possible? pp. 1-4 Downloads
Arturo Casadevall
More science friction for less science fiction pp. 1-4 Downloads
Jennifer A Byrne and Stefan Stender

Volume 23, issue 4, 2025

Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila pp. 1-34 Downloads
Kun Wu, Juanyu Zhou, Yiming Tang, Qiaoqiao Zhang, Lishou Xiong, Xiaorong Li, Zhangpeng Zhuo, Mei Luo, Yu Yuan, Xingzhu Liu, Zhendong Zhong, XiaoXin Guo, Zihua Yu, Xiao Sheng, Guanzheng Luo and Haiyang Chen
Removing facial features from structural MRI images biases visual quality assessment pp. 1-19 Downloads
Céline Provins, Élodie Savary, Thomas Sanchez, Emeline Mullier, Jaime Barranco, Elda Fischi-Gómez, Yasser Alemán-Gómez, Jonas Richiardi, Russell A Poldrack, Patric Hagmann and Oscar Esteban
Autophagy-related protein Atg11 is essential for microtubule-mediated chromosome segregation pp. 1-38 Downloads
Md Hashim Reza, Rashi Aggarwal, Jigyasa Verma, Nitesh Kumar Podh, Ratul Chowdhury, Gunjan Mehta, Ravi Manjithaya and Kaustuv Sanyal

Volume 23, issue 3, 2025

On improving the sustainability of peer review pp. 1-3 Downloads
Daniel Routledge, Nonia Pariente and On Behalf of the PLOS Biology Staff Editors
The IBEX Knowledge-Base: A central resource for multiplexed imaging techniques pp. 1-7 Downloads
Andrea J Radtke, Ifeanyichukwu U Anidi, Leanne Arakkal, Armando J Arroyo-Mejias, Rebecca T Beuschel, Katy Börner, Colin J Chu, Beatrice Clark, Menna R Clatworthy, Jake Colautti, Fabian Coscia, Joshua Croteau, Saven Denha, Rose Dever, Walderez O Dutra, Sonja Fritzsche, Spencer Fullam, Michael Y Gerner, Anita Gola, Kenneth J Gollob, Jonathan M Hernandez, Jyh Liang Hor, Hiroshi Ichise, Zhixin Jing, Danny Jonigk, Evelyn Kandov, Wolfgang Kastenmüller, Joshua F E Koenig, Rosa K Kortekaas, Aanandita Kothurkar, Alexandra Y Kreins, Ian T Lamborn, Yuri Lin, Katia Luciano Pereira Morais, Aleksandra Lunich, Jean C S Luz, Ryan B MacDonald, Chen Makranz, Vivien I Maltez, John E McDonough, Ryan V Moriarty, Juan M Ocampo-Godinez, Vitoria M Olyntho, Annette Oxenius, Kartika Padhan, Kirsten Remmert, Nathan Richoz, Edward C Schrom, Wanjing Shang, Lihong Shi, Rochelle M Shih, Emily Speranza, Salome Stierli, Sarah A Teichmann, Tibor Z Veres, Megan Vierhout, Brianna T Wachter, Adam K Wade-Vallance, Margaret Williams, Nathan Zangger, Ronald N Germain and Ziv Yaniv
Navigation strategies in Caenorhabditis elegans are differentially altered by learning pp. 1-24 Downloads
Kevin S Chen, Anuj K Sharma, Jonathan W Pillow and Andrew M Leifer
Navigating your US bioscience career into the 2030s pp. 1-4 Downloads
Peter J Hotez

Volume 23, issue 2, 2025

vmTracking enables highly accurate multi-animal pose tracking in crowded environments pp. 1-44 Downloads
Hirotsugu Azechi and Susumu Takahashi
New solutions for antibiotic discovery: Prioritizing microbial biosynthetic space using ecology and machine learning pp. 1-3 Downloads
Marnix H Medema and Gilles P van Wezel

Volume 23, issue 1, 2025

Spontaneous slow cortical potentials and brain oscillations independently influence conscious visual perception pp. 1-33 Downloads
Lua Koenig and Biyu J He
How can modeling responsibly inform decision-making in malaria? pp. 1-5 Downloads
Jaline Gerardin and Melissa A Penny
Cost-benefit tradeoff mediates the transition from rule-based to memory-based processing during practice pp. 1-24 Downloads
Guochun Yang and Jiefeng Jiang
Page updated 2025-10-11