Challenges in interpreting cytokine data in COVID-19 affect patient care and management

Stephen Y Wang, Takehiro Takahashi, Alexander B Pine, William E Damsky, Michael Simonov, Yanhua Zhang, Elizabeth Kieras, Christina C Price, Brett A King, Mark D Siegel, Gary V Desir, Alfred I Lee, Akiko Iwasaki and Hyung J Chun

PLOS Biology, 2021, vol. 19, issue 8, 1-5

Abstract: Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experience gained during the COVID-19 pandemic.The importance of cytokine storms in COVID-19 continues to be widely debated. This Perspective article discusses the challenges in using cytokine measurement in COVID-19 and other disease states as we strive to improve our understanding and treatment of COVID-19.

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pbio00:3001373

DOI: 10.1371/journal.pbio.3001373

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