Tolerance measured at one developmental stage mispredicts climate resilience in an animal with a complex life cycle

Hao Song, Tingyu Shi, Meijie Yang, Xiaoyan Liu, Zhuoqing Li, Pu Shi, Yu Wu, Bassem Allam, Andrew Jeffs, Bradley Skelton and Tao Zhang

PLOS Biology, 2026, vol. 24, issue 10, 1-25

Abstract: Forecasts of whether marine species can evolve fast enough to survive climate change rely largely on single-stage tolerance assays, tacitly assuming that tolerance measured at one developmental stage reflects adaptive capacity across the organism’s life cycle. We test this assumption in a common marine bivalve (Mercenaria mercenaria) and find that it fails in sign, not degree: larval and post-metamorphic tolerance to end-century ocean acidification are strongly negatively correlated (r = −0.53, 95% CI [−0.69, −0.33]) across family-level, pedigree-conditioned and animal model estimates, with pervasive rank reversals among the top performers of each stage. A multivariate analysis of the among-family covariance matrix G shows why: under acidification, 57% of the among-family variance collapses onto a single dominant axis that loads positively on every larval trait and negatively on every post-metamorphic trait, whereas under ambient conditions the same families show no cross-stage covariance at all. Acidification therefore does not merely depress performance—it reorganizes the genetic architecture into a cross-stage conflict. Under ramping RCP 8.5 forcing this conflict geometry dictates the direction—not merely the magnitude—of adaptation: only balanced multi-stage selection preserves family diversity, whereas single-stage selection systematically erodes the opposite axis. In complex life cycles, resilience is a geometric property of ontogeny that forecasts cannot compress into a single-stage without inverting the sign of the answer.Forecasts of whether marine species can survive climate change rely largely on tolerance assays at one developmental stage. This study of the tolerance of an animal with a complex life cycle to end-century ocean acidification reveals cross-stage conflicts that impact the direction and magintude of adaptation.

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pbio00:3004079

DOI: 10.1371/journal.pbio.3004079

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