Risk factors for disruptions in tuberculosis care in Uganda during the COVID-19 pandemic

Peter D Jackson, Stella Zawedde Muyanja, Isaac Sekitoleko, Mudarshiru Bbuye, Madeline Helwig, Roma Padalkar, Mariam Hammad, Dennis Hopkinson and Trishul Siddharthan

PLOS Global Public Health, 2023, vol. 3, issue 6, 1-12

Abstract: Background: During the COVID-19 pandemic, TB mortality increased while diagnoses decreased, likely due to care disruption. In March, 2020, Uganda—a country with high TB burden, implemented a COVID-19 lockdown with associated decrease in TB diagnoses. This study aims to examine patient level risk factors for disruption in TB care during the COVID-19 pandemic in Uganda. This retrospective cross-sectional cohort study included six TB clinics in Uganda. Clustered sampling included phases of TB care and three time-periods: pre-lockdown, lockdown and post-lockdown. Characteristics of patients with TB care disruption (TBCD), defined as those with > 2 months of symptoms prior to diagnosis or who missed a TB clinic, and those without TB care disruption (non-TBCD) were analyzed between time-periods. 1,624 charts were reviewed; 1322 were contacted, 672 consented and completed phone interview; pre-lockdown (n = 213), lockdown (n = 189) and post-lockdown (n = 270). TBCD occurred in 57% (385/672) of patients. There was an increase in the proportion of urban patients in the TBCD and non-TBCD groups during post-lockdown (p

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pgph00:0001573

DOI: 10.1371/journal.pgph.0001573

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