Prevalence of aspiration pneumonia among stroke patients in Ethiopia: A systematic review and meta-analysis

Assefa Andargie Kassa, Getahun Gebre Bogale, Mekuanint Taddele, Tilahun Degu Tsega, Abebaw Molla, Wolde Melese and Segenet Zewdie

PLOS Global Public Health, 2025, vol. 5, issue 7, 1-17

Abstract: Aspiration pneumonia (AP) is a serious complication among stroke patients, increasing the risk of poor outcomes and death. Although a previous review in Ethiopia attempted to estimate its burden, it had methodological limitations. This study aimed to provide an updated and comprehensive estimate of the pooled prevalence of AP among stroke patients in Ethiopia. A systematic review and meta-analysis were conducted following PRISMA guidelines. Relevant studies were identified from electronic databases and grey literature. Data were analyzed using STATA version 17 with the metaprop package. A random-effects model with Freeman–Tukey double arcsine transformation was applied. Heterogeneity was assessed using I² and Cochran’s Q test. Subgroup analysis, meta-regression, and leave-one-out sensitivity analysis were conducted. Publication bias was evaluated using funnel plot symmetry and Egger’s test. A total of 27 studies involving 7,120 stroke patients were included. The pooled prevalence of AP was 24.26% (95% CI: 20.76%–27.95%), with significant heterogeneity (I² = 91.96%; p

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pgph00:0004869

DOI: 10.1371/journal.pgph.0004869

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